Spatial 2013: From spatial signalling to sensing spatiality

In recent years it has become increasingly clear that sophisticated and diverse mechanisms are required for information transfer and signaling WITHIN cells. It is now appreciated that diffusion alone is not sufficient to account for effective transfer of different signals from the cell surface to the nucleus against unfavorable enzymatic activities. Long distance communication within cells requires protected or facilitated mechanisms of signal propagation over any intracellular distance of more than a few micrometers. Furthermore, experimental observations and theoretical analyses show that information encoded in movement of large molecular complexes or nucleic acids likewise requires facilitated mechanisms of intracellular transport or propagation.
Different communities of researchers are interested in spatial aspects of propagation of intracellular signals and information within cells, including theoreticians, cell biologists and neurobiologists. Information transfer within large and morphologically complex cells (such as neurons) requires specialized mechanisms to facilitate signals propagation. Proposed mechanisms include signaling 'waves' propagating over distance or motor driven transport of signaling endosomes or signaling complexes. Malfunction of intracellular propagation of survival and other signals in cells is tightly linked with disease etiology in the nervous and immune systems, thus both basic researchers and clinicians are equally interested in the mechanisms involved.
The aim of this Conference Series is to provide a unique platform for communication and interaction between the scientists involved in these diverse research communities.
Conference themes will include:
Computational Approaches to Cell Biology
Intracellular Dynamics in Spatial Signaling
Synthetic and Chemical Biology Approaches
RNA Localization for Spatial Specification of Signaling
Robustness in Signaling Networks
Long Distance Communication in Neuronal Processes
Dynamics and Kinetics of Cellular Signaling
Cell Size Sensing
Hot topics talks selected from abstract submissions
+ show speakers and program

Claudia Bagni
Katholieke Universiteit Leuven
Belgium
Naama Barkai
Weizmann Institute of Science
Israel
Philippe Bastiaens
Max Planck Institute for Molecular Physiology
Germany
Vivian Budnik
University of Massachusetts
USA
Valeria Cavalli
Washington University in St Louis
USA
Aaron Ciechanover
Technion – Israel Institute of Technology
Israel
Eleanor Coffey
Turku Centre for Biotechnology
Finland
Peter Devreotes
Johns Hopkins University
USA
Andrew Goryachev
University of Edinburgh
UK
John Hancock
University of Texas Health Science Center at Houston
USA
Christine Holt
University of Cambridge
UK
Casper Hoogenraad
Utrecht University
The Netherlands


Sandrine Humbert
Institut Curie
France
Walter Kolch
University College Dublin
Ireland
Michael Kreutz
Leibniz Institute for Neurobiology
Germany
Akihiro Kusumi
Kyoto University
Japan
Andre Levchenko
Johns Hopkins University
USA
Neil McDonald
Cancer Research UK London Research Institute
UK
Giampietro Schiavo
Cancer Research UK London Research Institute
UK
Stanislav Shvartsman
Princeton University
USA
Joerg Stelling
ETH Zurich
Switzerland
Thomas Surrey
Cancer Research UK London Research Institute
UK
Jeffery Twiss
Drexel University
USA
Marino Zerial
Max Planck Institute of Molecular Cell Biology and Genetics
Germany

24 Apr - 28 Apr 2013
Dead Sea
Israel
meeting website