Cardiac Remodeling, Signaling, Matrix and Heart Function

The Keystone Symposia conference on “Cardiac Remodeling, Signaling, Matrix and Heart Function” will highlight recent scientific advances in cardiac biology and heart failure research and relate these insights to the development of novel clinical therapeutics that may impact patient care. This meeting will bring together both academic and industrial scientists employing state-of-the-art technologies encompassing the fields of stem cell science, tissue regeneration, bioengineering, non-coding RNAs, human and animal genetics, calcium signaling, autophagy and proteolysis, cardiac mechanics, and cardiac matrix biology. The translation of basic scientific discovery to pre-clinical drug development will be emphasized. In addition, there will be a workshop that details recent advances in development of novel therapeutic agents to treat heart failure and arrhythmias. This conference is organized to provide scientists with diverse areas of expertise knowledge of technological applications and biological insights about the development and pathophysiology of cardiac dysfunction and arrhythmias. The four-day program is designed for a wide audience of academic and industrial basic, translational and clinical scientists. Interaction between scientists will be promoted through lectures, poster sessions, informal discussions and workshops.
+ show speakers and program
SUNDAY, APRIL 7

16:00—20:00
Arrival and Registration

Ballroom Lobby

MONDAY, APRIL 8

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 03/07/2013

Ballroom 2-3
Bruce M. Spiegelman, Harvard Medical School, USA
The Regulation of Physiologic Cardiac Growth by C/EBP Transcription Factors

09:00—12:00
Regenerating Injured Myocardium
Registered attendees can view abstracts starting on 03/07/2013

Ballroom 2-3
Deepak Srivastava, Gladstone Institute of Cardiovascular Disease, USA
Genetic Reprogramming of Fibroblasts in the Myocardium

Eric N. Olson, University of Texas Southwestern Medical Center at Dallas, USA
In situ Generation of Cardiac Myocytes

William T. Pu, Children's Hospital, Harvard Medical School, USA
Transcriptional Pathways in Cardiac Regeneration

Issei Komuro, Osaka University Graduate School, Japan
Cardiac Angiogenesis and Myogenesis

09:40—10:00
Coffee Break

Ballroom Lobby
12:00—13:00
Poster Setup

Superior/Superior Lobby
13:00—22:00
Poster Viewing

Superior/Superior Lobby

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
Bioengineering and Tissue Repair
Registered attendees can view abstracts starting on 03/07/2013

Ballroom 2-3
Joseph C. Wu, Stanford University, USA
Imaging Cardiac Stem Cell Therapy

Richard T. Lee, Harvard University, USA
Bioengineering to Promote Cardiac Regeneration

Josef M. Penninger, Institute of Molecular Biotechnology GmbH, Austria
Apelin and ACE2 Regulate Cardiac Fibrosis and Function

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

Superior/Superior Lobby
19:30—22:00
Poster Session 1

Superior/Superior Lobby

TUESDAY, APRIL 9

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—11:00
Genetic Causes of Cardiomyopathy
Registered attendees can view abstracts starting on 03/07/2013

Ballroom 2-3
Elizabeth M. McNally, University of Chicago, USA
Modifier Genes for Heart and Muscle Disease

Christine E. Seidman, Harvard Medical School, USA
Cardiac Fibrosis in Hypertrophic Cardiomyopathy

Howard A. Rockman, Duke University Medical Center, USA
The Use of Drosophila Genetic Screens to Investigate Cardiomyopathy

Xuejun Wang, University of South Dakota, USA
Protein Quality Control in Cardiac Proteinopathies

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

Ballroom Lobby
11:00—13:00
Poster Setup

Superior/Superior Lobby
13:00—22:00
Poster Viewing

Superior/Superior Lobby

On Own for Lunch and Recreation

14:30—16:30
Workshop: Developing Novel Therapeutic Agents for Heart Failure

NOTE: Highlight recent pharmaceutical industry efforts to develop new drugs for the treatment of acute decompensated heart failure and chronic heart failure.

Ballroom 2-3
Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
MicroRNA Regulation of Cardiac Function
Registered attendees can view abstracts starting on 03/07/2013

Ballroom 2-3
Gerald W. Dorn, II, Washington University School of Medicine, USA
MicroRNA Regulation of Cardiac Hypertrophy and Failure

Edward E. Morrisey, University of Pennsylvania, USA
Promotion of Cardiomyocyte Proliferation by a miRNA-Hippo Mediated Pathway

Walter J. Koch, Temple University School of Medicine, USA
Regulation of Cardiac Hypertrophy by GRKs

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

Superior/Superior Lobby
19:30—22:00
Poster Session 2

Superior/Superior Lobby

WEDNESDAY, APRIL 10

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—11:00
Calcium Signaling, Protein Kinases and Cardiac Dysfunction
Registered attendees can view abstracts starting on 03/07/2013

Ballroom 2-3
Joan Heller Brown, University of California, San Diego, USA
Localized Calcium Signaling and CamKII

Steven R. Houser, Temple University School of Medicine, USA
Calcium Influx Pathways that Regulate Hypertrophy

Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
Calcium Signaling Pathways that Regulate Cardiac Growth

Mark E. Anderson, University of Iowa, USA
Calcium Signaling in Cardiac Arrhythmias

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

Ballroom Lobby
11:00—13:00
Poster Setup

Superior/Superior Lobby
13:00—22:00
Poster Viewing

Superior/Superior Lobby

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
Cardiac Autophagy and Proteolysis
Registered attendees can view abstracts starting on 03/07/2013

Ballroom 2-3
Norbert Perrimon, Harvard Medical School, USA
FoxO and 4EBP Regulation of Drosophila Muscle Physiology

Roberta Gottlieb, San Diego State University, USA
Mitophagy and Cardioprotection

Asa B. Gustafsson, University of California, San Diego, USA
Mitochondrial Autophagy in Ischemic Myocardium

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

Superior/Superior Lobby
19:30—22:00
Poster Session 3

Superior/Superior Lobby

THURSDAY, APRIL 11

07:00—08:00
Breakfast

Golden Cliff/Eagles
08:00—11:00
Cardiac Mechanics
Registered attendees can view abstracts starting on 03/07/2013

Ballroom 2-3
Fady Malik, Cytokinetics Inc., USA
Cardiac Myosin Activators for the Treatment of Heart Failure

Jil C. Tardiff, University of Arizona, USA
Thin Filament Function in Cardiac Physiology

Henk Granzier, University of Arizona, USA
The Role of Titin in Cardiac Function and Disease

Samantha Harris, University of California, Davis, USA
Cardiac Myosin Binding Protein-C

Short Talk(s) Chosen from Abstracts

09:00—09:20
Coffee Break

Ballroom Lobby

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Ballroom Lobby
17:00—19:00
Cardiac Extracellular Matrix in Disease
Registered attendees can view abstracts starting on 03/07/2013

Ballroom 2-3
Ronglih Liao, Brigham and Women's Hospital, USA
New Insights into Amyloid Cardiomyopathy

Thomas Eschenhagen, University Medical Center Hamburg Eppendorf, Germany
Cardiac Tissue Engineering

Anthony J. Muslin, Novartis Institutes for BioMedical Research, Inc., USA
Developing Drugs to Reduce Cardiac Fibrosis and Improve Function

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

Ballroom 2-3
20:00—23:00
Entertainment

Ballroom 2-3

FRIDAY, APRIL 12


Departure


*Session Chair †Speaker invited, not yet responded.

7 Apr - 12 Apr 2013
Snowbird
United States of America
meeting website