Neuronal Control of Appetite, Metabolism and Weight

Obesity and Type 2 Diabetes associate with a disruption in energy, glucose and lipid homeostasis. New exciting developments continue to indicate a key role for the Central Nervous System in the homeostatic control of systemic metabolic processes and ultimately body weight. A goal of this meeting is to bring together basic and clinical scientists from academia and the pharmaceutical industry studying neuronal control of appetite, metabolism and body weight or related complementary fields such as addiction/reward, cellular stress or inflammation) to share novel and relevant insights with relevance for human obesity, diabetes and metabolic disease. The meeting seeks to trigger progress towards a novel and improved model, which integrates existing knowledge with novel discoveries on central nervous system mechanisms activated by hormones or nutrients that regulate systemic metabolism in order to provide the research in this field with a valuable new tool with combined relevance for both basic science and clinical research.
+ show speakers and program
SUNDAY, MARCH 17

16:00—20:00
Arrival and Registration


MONDAY, MARCH 18

07:00—08:00
Breakfast

08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 02/17/2013

Richard Palmiter, University of Washington, USA

09:00—12:00
Hypothalamic Inflammation, ER Stress and Mitochondrial Function
Registered attendees can view abstracts starting on 02/17/2013

Gökhan S. Hotamisligil, Harvard University, USA
ER Stress and Control of Metabolism

Dongsheng Cai, Albert Einstein College of Medicine, USA
Autophagy and Inflammation in Hypothalamic Neurons and Central Control of Metabolism

Umut Ozcan, Children's Hospital Boston, Harvard Medical School, USA
Hypothalamic Inflammation, ER Stress and Metabolic Control

Jens C. Brüning, Institute for Genetics, University of Cologne, Germany
Insulin Receptors in the Brain: Where Do They Matter?

Short Talk Chosen from Abstracts

09:40—10:00
Coffee Break

12:00—13:00
Poster Setup

13:00—22:00
Poster Viewing


On Own for Lunch and Recreation

14:30—16:30
Workshop 1: Is the CNS Still a Relevant Pharmaceutical Target for Metabolic Disease?

16:30—17:00
Coffee Available

17:00—19:00
Addiction and Reward in the CNS Control of Metabolism
Registered attendees can view abstracts starting on 02/17/2013

Jeffrey M. Friedman, Rockefeller University, USA
Neuroendocrine Control of Hedonic Feeding Behavior

Tamas L. Horvath, Yale University School of Medicine, USA
A Role for the Arcute Nucleus in Reward and Complex Behaviors

Dana M. Small, Yale University School of Medicine, USA
Imaging Addiction to Food in Humans

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

19:30—22:00
Poster Session 1


TUESDAY, MARCH 19

07:00—08:00
Breakfast

08:00—11:00
Nutrient Sensing and the Brain
Registered attendees can view abstracts starting on 02/17/2013

Daniele Piomelli, University of California, Irvine, USA
Lipid Sensing and the Gut-Brain Axis

Tony K.T. Lam, University of Toronto, Canada
Nutrient Sensing in the Gut and the Brain

Bradford B. Lowell, Beth Israel Deaconess Medical Center, USA
Circuits Regulating Energy Balance – Functional Dissection and Role of Synaptic Mechanisms

Sabrina Diano, Yale University School of Medicine, USA
Glucose Sensing and Hypothalamic Neuropeptide Processing

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

11:00—13:00
Poster Setup

13:00—22:00
Poster Viewing


On Own for Lunch and Recreation

14:30—16:30
Workshop 2: Challenges of the Publishing Process: How to Write a Scientific Masterpiece

16:30—17:00
Coffee Available

17:00—19:00
Dissecting CNS Control of Metabolism I
Registered attendees can view abstracts starting on 02/17/2013

Kendra K. Bence, University of Pennsylvania, USA
The Role of Phosphatase in the Neuronal Control of Energy Balance

Christoph Buettner, Mount Sinai School of Medicine, USA
CNS Control of Fat Metabolism

Scott Sternson, HHMI/Janelia Farm Research Campus, USA
A Novel Hypothalamic Memory Switch in the Regulation of Energy Homeostasis

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

19:30—22:00
Poster Session 2


WEDNESDAY, MARCH 20

07:00—08:00
Breakfast

08:00—11:00
Gut-Brain Interactions in the Control of Systemic Metabolism
Registered attendees can view abstracts starting on 02/17/2013

Daniel J. Drucker, Samuel Lunenfeld Research Institute, Canada
The Biology of Incretins: Pleiotropic Metabolic Actions in Health and Disease

Remy G. Burcelin, Institute of Molecular Medicine, France
The Role of GLP-1 for the Gut-Brain Axis

Richard D. DiMarchi, Indiana University, USA
Novel Drug Treatments for Metabolic Disease: From Gut Hormones to Polypharmacy

Rachel L. Batterham, University College London, UK
Gut Peptide and Gastric Bypass Surgeries in Type 2 Diabetes

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

11:00—13:00
Poster Setup

13:00—22:00
Poster Viewing


On Own for Lunch and Recreation

14:30—16:30
Workshop 3: Novel Methodological Approaches to the Study of CNS Control of Metabolism

NOTE: Novel Biotechnology, Brain Imaging in Rodents, Novel Genetice Targeting Approaches, Nanotechnology

Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

17:00—19:00
Dissecting CNS Control of Metabolism II
Registered attendees can view abstracts starting on 02/17/2013

Domenico Accili, Columbia University, USA
FoxO1 Targets Regulating Energy Balance in the Central Nervous System

Randy J. Seeley, University of Cincinnati, USA
CNS PPAR-gamma

Markus Stoffel, Institute of Molecular Systems Biology, Switzerland
CNS Foxa2

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

19:30—22:00
Poster Session 3


THURSDAY, MARCH 21

07:00—08:00
Breakfast

08:00—11:00
Neurocircuitry and Systemic Control of Metabolism
Registered attendees can view abstracts starting on 02/17/2013

Lori M. Zeltser, Columbia University, USA
Hypothalamic Development and Systemic Control of Metabolism

Martin G. Myers, Jr., University of Michigan, USA
Leptin Receptors in the Brain: Where Do They Matter?

Michael A. Cowley, Monash University, Australia
Leptin Modulation of DMH Circuits Controlling the Sympathetic Nervous System

Roberto Coppari, University of Texas Southwestern Medical Center, USA
Metabolic Actions of Hypothalamic SIRT1

Short Talk(s) Chosen from Abstracts

09:00—09:20
Coffee Break


On Own for Lunch and Recreation

16:30—17:00
Coffee Available

17:00—19:00
Glia Cells and CNS Control of Metabolism
Registered attendees can view abstracts starting on 02/17/2013

Michael W. Schwartz, University of Washington, USA
Hypothalamic Inflammation: 'Primum movens' of the Metabolic Syndrome?

Matthias H. Tschöp, HelmholtzZentrum München, Germany
A Role for Hypothalamic Astrocytes in Obesity and Diabetes

Licio A. Velloso, University of Campinas, Brazil
A Role for Hypothalamic Microglia in Obesity and Diabetes

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

20:00—23:00
Entertainment


FRIDAY, MARCH 22


Departure


*Session Chair †Speaker invited, not yet responded.

17 Mar - 22 Mar 2013
Banff
Canada
meeting website