Precision Genome Engineering and Synthetic Biology: Designing Genomes and Pathways

Now that we know the sequences of many genomes, from a wide variety of organisms and even from individuals with unique characteristics, many researchers have turned to making intentional modifications of those genomes. Purposes of those modifications include: introducing mutations to evaluate gene function, production of models for human genetic disease, gene correction, radical redesign of genome structure, and the generation of novel cellular networks and pathways. This conference will bring together scientists who are: 1) developing tools for precision genome engineering; 2) using those tools for specific purposes in a wide range of organisms, including humans; 3) creating whole synthetic genomes with prospects for wholesale reengineering; 4) engineering cells with novel pathways and properties. Exchange of cutting-edge information regarding approaches, accomplishments and ambitions will augment the capabilities of each group. The meeting will provide an outstanding forum for students, postdoctoral fellows, and senior investigators who envision careers in genome and pathway design.
+ show speakers and program
SUNDAY, MARCH 17

16:00—20:00
Arrival and Registration

Foyer

MONDAY, MARCH 18

07:00—08:00
Breakfast

Summit Gallery
08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 02/17/2013

Peaks 4-5
Frances H. Arnold, California Institute of Technology, USA
Evolutionary Engineering of Proteins and Pathways

09:00—11:30
Pathway Engineering
Registered attendees can view abstracts starting on 02/17/2013

Peaks 4-5
Douglas Densmore, Boston University, USA
Clotho - CAD for Synthetic Biology

Stephen del Cardayre, LS9, Inc., USA
Engineering E. coli Fatty Acid Metabolism for Sustainable Fuel and Chemical Production

Ron Weiss, Massachusetts Institute of Technology, USA
Synthetic Biology: From Parts to Modules to Therapeutic Systems

Short Talk(s) Chosen from Abstracts

09:40—10:00
Coffee Break

Foyer
11:30—13:00
Poster Setup

Peaks 1-3
13:00—22:00
Poster Viewing

Peaks 1-3

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Zinc-Finger Nucleases and TALENs
Registered attendees can view abstracts starting on 02/17/2013

Peaks 4-5
Dana Carroll, University of Utah School of Medicine, USA
Parameters Affecting ZFN- and TALEN-Mediated Gene Targeting

Daniel Voytas, University of Minnesota, USA
ZFNs and TALENs in Plants

Thomas Lahaye, Ludwig-Maximilians-University Munich, Germany
TALEs and TALENs: New Tools for Genome Editing and Transcriptome Modulation

Toni Cathomen, Hannover Medical School, Germany
Comparing ZFNs and TALENs

19:15—20:15
Social Hour w/ Lite Bites

Peaks 1-3
19:30—22:00
Poster Session 1

Peaks 1-3

TUESDAY, MARCH 19

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Engineering Genomes
Registered attendees can view abstracts starting on 02/17/2013

Peaks 4-5
Daniel Gibson, J. Craig Venter Institute, USA
Synthetic Microbial Genomes

Farren Isaacs, Yale University, USA
Programming Genomes to Re-engineer Life's Functional Repertoire

Sriram Kosuri, Wyss Institute, USA
Reading and Writing DNA

Jef D. Boeke, Johns Hopkins University School of Medicine, USA
Synthetic Yeast Genome

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

Foyer
11:00—13:00
Poster Setup

Peaks 1-3
13:00—22:00
Poster Viewing

Peaks 1-3

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Genome Engineering in Humans and Other Animals
Registered attendees can view abstracts starting on 02/17/2013

Peaks 4-5
Philip D. Gregory, Sangamo BioSciences, Inc., USA
Clincal Trials with ZFNs

Detlev Arendt, EMBL Heidelberg, Germany
ZFN-Mediated Gene Targeting in Platynereis, a New Marine Molecular Model Organism

Scott C. Fahrenkrug, University of Minnesota, USA
Engineering of Food Animal Genomes

Luigi M. Naldini, San Raffaele Telethon Institute, Italy
Gene Targeting in Human Stem Cells by ZFNs

19:00—20:00
Social Hour w/ Lite Bites

Peaks 1-3
19:30—22:00
Poster Session 2

Peaks 1-3

WEDNESDAY, MARCH 20

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Design in Synthetic Biology
Registered attendees can view abstracts starting on 02/17/2013

Peaks 4-5
Tanja Kortemme, University of California, San Francisco, USA
Computational Design of Proteins, Interactions and Networks

Petra Schwille, Institute of Biophysics, Germany
Design Features of Protein Gradient and Pattern Formation

Jason W. Chin, MRC, Laboratory of Molecular Biology, UK
Building on Orthogonal Translational Apparatus

Yaakov (Kobi) Benenson, ETH Zürich, Switzerland
Designing Anti-Cancer Circuits Based on miRNA Expression Patterns

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

Foyer

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Targeting with Transposons, Integrases and Homing Endonucleases
Registered attendees can view abstracts starting on 02/17/2013

Peaks 4-5
Nancy L. Craig, Johns Hopkins University School of Medicine, USA
Transposon Target Selection

Michele P. Calos, Stanford University School of Medicine, USA
Integrase-Mediated Gene Addition to Create and Correct Induced Pluripotent Stem Cells

Barry Stoddard, Fred Hutchinson Cancer Research Center, USA
Engineered Homing Endonucleases for Gene Targeting via Single- and Double-Strand Breaks

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

Peaks 1-3
19:30—22:00
Poster Session 3

Peaks 1-3

THURSDAY, MARCH 21

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Programming Organismal Behavior
Registered attendees can view abstracts starting on 02/17/2013

Peaks 4-5
Virginia W. Cornish, Columbia University, USA
Co-Opting Cells for Directed Evolution

Jeff Hasty, University of California, San Diego, USA
Engineered Gene Circuits: From Oscillators to Synchronized Clocks and Biopixels

Christopher Voigt, Massachusetts Institute of Technology, USA
Programming Devices and Networks

June I. Medford, Colorado State University, USA
Synthetic Signal Transduction and Design of New Traits

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

Foyer

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Engineering Biofuel and Specialty Chemical Production
Registered attendees can view abstracts starting on 02/17/2013

Peaks 4-5
Sang Yup Lee, Korea Advanced Institute of Science and Technology (KAIST), South Korea
Redesigning Cellular Metabolism for Chemicals Production

Edward M. Rubin, Lawrence Berkeley National Laboratory, USA
Synthetic Metagenomics

Zach Serber, Amyris, USA
Engineering Biofuel and Specialty Chemical Platforms in Yeast

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

Peaks 1-3
20:00—23:00
Entertainment

Peaks 1-3

FRIDAY, MARCH 22


Departure


*Session Chair †Speaker invited, not yet responded.

17 Mar - 22 Mar 2013
Breckenridge
United States of America
meeting website