Myeloid Cells: Regulation and Inflammation

Recent results have shown that during inflammatory processes, myeloid cells exhibit extensive plasticity of their phenotype in response to numerous stimuli. This characteristic directly affects lymphocyte polarization and activity and is controlled by changes both at transcriptional and translational level. This previously unanticipated degree of epigenetic control of myeloid cells, which affects both innate and adaptive immune responses, is likely to impact several aspects of future studies in human immunology and to inform on immunotherapeutic strategies. This Keystone Symposia meeting will cover topical aspects of basic myeloid cell biology and their interface with clinical research, bringing together scientists and clinicians working on all the subtypes of myeloid cells in health and disease, from neutrophils and monocytes to macrophages and dendritic cells. The speakers will provide an overview of myeloid cell ontogeny, role of different myeloid cell subtypes in the modulation of innate and adaptive immunity, antigen capture and presentation, mobilization from the bone marrow and trafficking during inflammatory responses. The symposium will touch on multiple areas central to contemporary immunology and cell biology, including the interface between innate and adaptive immunity, as well as the mechanisms enforcing immunosuppression in cancer and infectious diseases.
+ show speakers and program
TUESDAY, FEBRUARY 19

16:00—20:00
Arrival and Registration

Longs Peak Foyer

WEDNESDAY, FEBRUARY 20

07:00—08:00
Breakfast

Longs/Quandary Peaks
08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 01/19/2013

Grays Peak
Siamon Gordon, University of Oxford, UK
Pro- and Anti-Inflammatory Role of Myeloid Cells

09:00—12:00
Myeloid Lineage Differentiation
Registered attendees can view abstracts starting on 01/19/2013

Grays Peak
Irving L. Weissman, Stanford University, USA
Differentiation of GMP into Granulocytes and Monocytes

Paul S. Frenette, Albert Einstein College of Medicine, USA
Mobilization from the Bone Marrow of Myeloid Cells

Paresh Vyas, University of Oxford, UK
Lineage Differentiation of AML

Michael H. Sieweke, Centre d'Immunologic Marseille-Luming, France
Transcriptional Control of Myeloid Cell Fate and Self Renewal

Short Talk Chosen from Abstracts

09:40—10:00
Coffee Break

Longs Peak Foyer
12:00—13:00
Poster Setup

Longs/Quandary Peaks
13:00—22:00
Poster Viewing

Longs/Quandary Peaks

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Plasticity of Myeloid Cells
Registered attendees can view abstracts starting on 01/19/2013

Grays Peak
David M. Mosser, University of Maryland, USA
Macrophage Plasticity

Vincenzo Cerundolo, University of Oxford, UK
Plasticity of PMN in Cancer

Judith E. Allen, University of Edinburgh, UK
Local Macrophage Proliferation

19:00—20:00
Social Hour w/ Lite Bites

Longs/Quandary Peaks
19:30—22:00
Poster Session 1

Longs/Quandary Peaks

THURSDAY, FEBRUARY 21

07:00—08:00
Breakfast

Longs/Quandary Peaks
08:00—11:00
Myeloid Cells during Inflammation
Registered attendees can view abstracts starting on 01/19/2013

Grays Peak
Ajay Chawla, University of California, San Francisco, USA
Monocyte Subsets and Metabolic Disease

Eric G. Pamer, Memorial Sloan-Kettering Cancer Center, USA
Pathogens and Mucosal Immunity

Christopher K. Glass, University of California, San Diego, USA
A Genome-Wide View of Macrophage Activation

Arturo Zychlinsky, Max Planck Institute for Infection Biology, Germany
NETs – From Infection to Autoimmunity

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00—13:00
Poster Setup

Longs/Quandary Peaks
13:00—22:00
Poster Viewing

Longs/Quandary Peaks

On Own for Lunch and Recreation

14:30—16:30
Workshop 1: Inflammation and Chemokine Receptors

Grays Peak
Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Myeloid Cell Migration and Trafficking
Registered attendees can view abstracts starting on 01/19/2013

Grays Peak
Gwendalyn J. Randolph, Washington University, USA
Monocyte Migration

Paul Kubes, University of Calgary, Faculty of Medicine, Canada
Trafficking of Neutrophils

Frederic Geissmann, Kings College London, UK
Inflammatory Monocytes

19:00—20:00
Social Hour w/ Lite Bites

Longs/Quandary Peaks
19:30—22:00
Poster Session 2

Longs/Quandary Peaks

FRIDAY, FEBRUARY 22

07:00—08:00
Breakfast

Longs/Quandary Peaks
08:00—11:00
Signaling Events
Registered attendees can view abstracts starting on 01/19/2013

Grays Peak
Luke A. J. O'Neill, Trinity College Dublin, Ireland
MicroRNAs in TLR Signaling Events

Caetano Reis e Sousa, Cancer Research UK, London Research Institute, UK
Innate Immune Recognition of Cell Death

Jenny P. Ting, University of North Carolina at Chapel Hill, USA
Inflammasomes

Alan Aderem, Seattle BioMed, USA
Innate Mechanisms for Intracellular Bacteric

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00—13:00
Poster Setup

Longs/Quandary Peaks
13:00—22:00
Poster Viewing

Longs/Quandary Peaks

On Own for Lunch and Recreation

14:30—16:30
Workshop 2: Myeloid Regulatory Cells

Grays Peak
Short Talks Chosen from Abstracts

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Myeloid Cells during Pathogen Infections
Registered attendees can view abstracts starting on 01/19/2013

Grays Peak
Denise M. Monack, Stanford University, USA
Inflammasome Activation and Bacterial Infections

Bali Pulendran, Emory University, USA
Immunlogical Signatures

John Schoggins, Rockefeller University, USA
Interferon Antiviral Responses

19:00—20:00
Social Hour w/ Lite Bites

Longs/Quandary Peaks
19:30—22:00
Poster Session 3

Longs/Quandary Peaks

SATURDAY, FEBRUARY 23

07:00—08:00
Breakfast

Longs/Quandary Peaks
08:00—11:00
Myeloid Cells Modulating Adaptive Immune Responses
Registered attendees can view abstracts starting on 01/19/2013

Grays Peak
Miriam Merad, Mount Sinai Medical Center, USA
Cutaneous DC and T Cells

Ronald N. Germain, NIAID, National Institutes of Health, USA
Myeloid Cell Localization, Interactions and Trafficking in Tissues

Kenneth M. Murphy, Washington University School of Medicine, USA
DC and Adaptive Immune Response

Matteo Iannacone, San Raffaele Scientific Institute, Italy
Lymph Node Macrophages and Antiviral Immune Responses

Short Talk(s) Chosen from Abstracts

09:00—09:20
Coffee Break

Longs Peak Foyer

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Myeloid Cells in Pathologies and in the Clinic
Registered attendees can view abstracts starting on 01/19/2013

Grays Peak
Virginia Pascual, Baylor Institute for Immunology Research, USA
Neutrophils and SLE

Jeffrey W. Pollard, Albert Einstein College of Medicine, USA
Macrophages and Tumor Progression

Alan Sher, NIAID, National Institutes of Health, USA
Talk Title to be Determined

19:00—20:00
Social Hour w/ Lite Bites

Longs/Quandary Peaks
20:00—23:00
Entertainment

Longs/Quandary Peaks

SUNDAY, FEBRUARY 24


Departure


*Session Chair †Speaker invited, not yet responded.

19 Feb - 24 Feb 2013
Keystone
United States of America
meeting website