Malaria

Malaria affects hundreds of millions of people and causes nearly 1 million deaths per year. The control and eventual eradication of malaria will require a concerted, multidisciplinary effort to decrease parasite infectivity through vaccines and anti-parasitic drugs, and by preventing transmission to the vertebrate host. In this meeting we will promote discussion of: 1) Innate and adaptive immune responses to Plasmodium infection and how the parasite interferes with these responses. We will also discuss the development of new adjuvants and anti-malaria vaccine strategies. 2) Basic aspects of Plasmodium cellular and population biology that affect infection and the development of drug resistance. 3) Plasmodium transmission, including gametocytogenesis and Plasmodium biology in the mosquito vector. This includes cellular and molecular aspects of parasite-mosquito interactions, field studies, functional genomics and the development of potential control strategies. 4) Severe malaria in endemic areas, recent advances in our understanding of the physiopathology of disease in humans and in animal models, and genome-based strategies to identify biomarkers of susceptibility to severe disease. Since basic and translational malaria research is eminently multidisciplinary, the 2013 Keystone Symposia meeting on Malaria will bring together researchers working in disciplines ranging from basic molecular studies to population biology. This encounter will promote the exchange of ideas to both deepen our understanding of malaria and to develop novel control measures. Furthermore, we anticipate that this meeting will enable us to identify and prioritize the next generation of challenges faced by the field.

Global Health Travel Award Deadline: August 21, 2012
+ show speakers and program

SUNDAY, JANUARY 20

16:00—20:00
Arrival and Registration

Prefunction

MONDAY, JANUARY 21

07:30—08:30
Breakfast

Ile de France III
08:30—09:30
Welcome and Keynote Address
Registered attendees can view abstracts starting on 12/20/2012

Ile de France I & II
Alan Cowman, Walter and Eliza Hall Institute of Medical Research, Australia
Mechanisms of Merozoite Invasion of Erythrocytes

09:30—12:45
Understanding Protective Immunity Against Plasmodium
Registered attendees can view abstracts starting on 12/20/2012

Ile de France I & II
Kevin Marsh, Kenya Medical Research Institute/Wellcome Trust Research Program, Kenya
Immune Responses to Malaria in Endemic Areas

Susan K. Pierce, NIAID, National Institutes of Health, USA
Antibody Responses and Development of B-Cell Memory, or Lack of It

Jean Langhorne, National Institute for Medical Research, UK
CD4 T Cells as Regulators and Effectors in the Immune Response to Malaria

William R. Heath, University of Melbourne, Australia
Innate Immune Responses: Role of Dendritic Cells in Protection and Pathogenesis

Fidel P. Zavala, Johns Hopkins Bloomberg School of Public Health, USA
Short Talk: Effector Liver-Resident CD8+ T Cells

10:50—11:10
Coffee Break

Prefunction
12:45—16:30
On Own for Lunch and Recreation

Ile de France III
12:45—13:45
Poster Setup

Ile de France III
13:45—22:00
Poster Viewing

Ile de France III
16:30—17:00
Coffee Available

Prefunction
17:00—19:00
New Approaches to Vaccination
Registered attendees can view abstracts starting on 12/20/2012

Ile de France I & II
Robert Sauerwein, Radboud University, Netherlands
Experimental Vaccination of Humans with Sporozites

Simon J. Draper, University of Oxford, UK
Combinatorial Vaccines Against Blood Stages

Sarah Reece, University of Edinburgh, UK
The Private Life of Parasites: Implications for Blocking Transmission

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

19:30—22:00
Poster Session 1

Ile de France III

TUESDAY, JANUARY 22

07:30—08:30
Breakfast

Ile de France III
08:30—11:30
Cellular and Molecular Biology of Plasmodium
Registered attendees can view abstracts starting on 12/20/2012

Ile de France I & II
Robert Ménard, Institut Pasteur, France
Molecular Basis of Plasmodium zoite Invasion into Host Cells

Volker Heussler, Institute of Cell Biology, Switzerland
Biology of Plasmodium Liver Stage

Maria M. Mota, Instituto de Medicina Molecular, Portugal
Development of Malaria Liver Stages

Manoj Duraisingh, Harvard School of Public Health, USA
Parasite Invasion in Genetically Modified Erythrocytes

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

Prefunction
11:00—13:00
Poster Setup

Ile de France III
13:00—22:00
Poster Viewing

Ile de France III

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Prefunction
17:00—19:00
Integrating Genomic Science and Population Biology
Registered attendees can view abstracts starting on 12/20/2012

Ile de France I & II
David J. Conway, London School of Hygiene and Tropical Medicine, UK
Parasite Population Genomics Identifies Targets of Immunity

Gilean McVean, University of Oxford, UK
Using de novo Assembly to Track Hypervariable Genes in Malaria Parasites

Michael T. Ferdig, Notre Dame University, USA
How Does the Parasite Fight Back?

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

Ile de France III
19:30—22:00
Poster Session 2

Ile de France III

WEDNESDAY, JANUARY 23

07:30—08:30
Breakfast

Ile de France III
08:00—08:30
Poster Setup

Ile de France III
08:30—11:30
Vector Biology and Malaria Transmission
Registered attendees can view abstracts starting on 12/20/2012

Ile de France I & II
Carolina V. Barillas-Mury, NIAID, National Institutes of Health, USA
Biology of Vector-Parasite Interactions

George Dimopoulos, Johns Hopkins University, USA
Anopheles Functional Genomics

Flaminia Catteruccia, Harvard School of Public Health, USA
Reproductive Biology of Anopheles Mosquitoes and Malaria Transmission

Luciano Andrade Moreira, Instituto de Pesquisas René Rachou-Fiocruz, Brazil
Use of Wolbachia for Control of Vector-Borne Diseases

Short Talk(s) Chosen from Abstracts

09:20—09:40
Coffee Break

Prefunction
08:30—17:00
Poster Viewing

Ile de France III
11:30—12:30
Lunch

Ile de France III
12:30—15:00
Poster Session 3

Ile de France III
15:00—15:30
Coffee Available

Prefunction
15:30—17:30
Biology of Plasmodium Transmission Stages
Registered attendees can view abstracts starting on 12/20/2012

Ile de France I & II
Andrew P. Waters, University of Glasgow, UK
RNA Biology and Zygote Development

Oliver Billker, Wellcome Trust Sanger Institute, UK
Signaling and Zygote Development

Friedrich Frischknecht, University of Heidelberg, Germany
Mechanisms of Plasmodium Sporozoite Motility

Short Talk Chosen from Abstracts

17:30—
On Own for Dinner


THURSDAY, JANUARY 24

07:30—08:30
Breakfast

Ile de France III
08:30—11:30
Epidemiology and Pathogenesis of Severe Malaria
Registered attendees can view abstracts starting on 12/20/2012

Ile de France I & II
Emelda Okiro, Kenya Medical Research Institute/Wellcome Trust Research Programme, Kenya
Epidemiology and Populational Aspects of Severe Disease

Terrie E. Taylor, Michigan State University, USA
Current Understanding of Pathogenesis of Severe Malaria in Humans

Christian Engwerda, Queensland Institute of Medical Research, Australia
Mechanisms of Pathogenesis in Experimental Models

Dominic Kwiatkowski, Oxford University and Wellcome Trust Sanger Institute, UK
Genetics of Disease Susceptibility

Short Talk(s) Chosen from Abstracts

09:00—09:20
Coffee Break

Prefunction

On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Prefunction
17:00—19:00
Mechanisms of Drug Resistance
Registered attendees can view abstracts starting on 12/20/2012

Ile de France I & II
David A. Fidock, Columbia University, USA
Cellular and Molecular Basis of Drug Resistance

Dyann F. Wirth, Harvard University, USA
Genetics Analysis of Drug Resistance

Xin-Zhuan Su, NIAID, National Institutes of Health, USA
Whole Genome Approaches to Identify Drugs that Work and Why Others Don't

Short Talk Chosen from Abstracts

19:00—20:00
Social Hour w/ Lite Bites

Ile de France III
20:00—23:00
Entertainment

Ile de France III

FRIDAY, JANUARY 25


Departure


*Session Chair †Speaker invited, not yet responded.

20 Jan - 25 Jan 2013
New Orleans
United States of America
meeting website