Mitochondrial Biochemistry, Physiology and Pathology

The aim of the FEBS Workshop "MiPsummer 2012" is to initiate and extend a network of teachers in mitochondrial physiology, and train early stage researchers in both the basics and cutting edge science of mitochondria. The Workshop will reflect the new diversity and dynamism of mitochondrial research, and bring together experts working on mitochondria in different fields, covering aspects from basic science to clinical orientation, from the molecular level to the patient. There will be an emphasis on understanding of the basic concepts and new methodological developments in measuring mitochondrial function and dysfunction.



Topics will include:

Introduction to mitochondria: basic concepts.
Mitochondrial bioenergetics: respiratory electron transfer system, ATP synthesis, carriers, protonmotive force.
Mitochondrial biogenesis: mtDNA, nucleoids, biogenesis, exercise/ training.
Mitochondria at the extremes: hypoxia, altitude, exercise, metabolic depression.
Mitochondrial pathology: ROS, mtDNA mutations, proton leak and cell death.
Mitochondria in cancer and cardiovascular disease.
Mitochondria in aging and neurodegeneration.
Mitochondrial methods: Visualisation, morphology, quantitation.
+ show speakers and program
Sir John Walker, MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK. walker@mrc-mbu.cam.ac.uk Mitochondrial ATP synthesis
Edmund Kunji, Dr., MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK. edmund.kunji@mrc-mbu.cam.ac.uk Mitochondrial carriers
Antonella Spinozzola, Dr., MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK. as1@mrc-mbu.cam.ac.uk Mitochondrial biogenesis
Michael Murphy, Dr, MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK. mpm@mrc-mbu.cam.ac.uk Mitochondrial ROS and medicine
Michael Duchen, Prof., Department of Physiology, University College London, Gower Street WC1E 6BT, London, UK. m.duchen@ucl.ac.uk Mitochondrial pathology
Erich Gnaiger, Prof., D. Swarovski Research Laboratory, Medical University Innsbruck, Anichstr. 35, A-6020 Innsbruck, Austria; Erich.Gnaiger@i-med.ac.at Mitochondrial respiratory physiology - Mitochondrial competence
Steven Hand, Prof., Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA; shand@lsu.edu Comparative physiology of mitochondria
Charles Hoppel, Prof, Center for Mitochondrial Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106-4981, USA. clh5@cwru.edu Diagnosing mitochondrial disease
Aviva Tolkovsky, Dr., Cambridge Centre for Brain Repair, University of Cambridge, Forvie Site, Cambridge CB20PY, UK amt@mole.bio.cam.ac.uk Mitochondria, autophagy & neurodegeneration.
Vilma Borutaite, Prof., Institute for Biomedical Research, Lithuanian University of Health Sciences, Eiveniu St, 3007 Kaunas LT; vilbor@vector.kmu.lt Mitochondria in Heart & Brain pathology
Rodrigue Rossignol, Dr., INSERM-EMI 9929 Université Victor Segalen-Bordeaux 2 146, rue Léo Saignat 33076 Bordeaux Cedex, FR; rossig@u-bordeaux2.fr Mitochondrial dynamics and cancer
Andrew Murray, Dr., Dept of Physiology, Development & Neuroscience, University of Cambridge, UK. ajm267@cam.ac.uk Mitochondrial adaptations to hypoxia, altitude and development
Kathrin Renner, Dr., St.-Georgen-Platz 6, 93047 Regensburg, DE; kathrin.renner-sattler@klinik.uni-regensburg.de Measuring cellular respiration and membrane potential
Bernard Korzeniewski, Prof., Faculty of Biochemistry, Biophysics and Biotechnology Jagiellonian University, 30-387 Krakow, Poland, e-mail: benio@mol.uj.edu.pl, Mitochondrial modelling.
Leonid Sazanov, MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK. leo.sazanov@mrc-mbu.cam.ac.uk Mitochondrial respiratory chain
Guy Brown, Dr, Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK; gcb@mole.bio.cam.ac.uk Mitochondria in cell death and degenerative disease

6 Jul - 12 Jul 2012
cambridge
United Kingdom
meeting website