San Antonio Breast Cancer Symposium

The 2012 CTRC-AACR San Antonio Breast Cancer Symposium
"An international scientific symposium for interaction and exchange among basic scientists and clinicians in breast cancer."


The 2012 CTRC-AACR San Antonio Breast Cancer Symposium is presented by the Cancer Therapy & Research Center at UT Health Science Center San Antonio, the American Association for Cancer Research, and Baylor College of Medicine. The driving force behind this collaboration is the shared mission of the organizations to advance progress against breast cancer. As exciting strides are made in the field of breast cancer research and treatment our program continues to present essential up-to-the minute information combined with engrossing discussion for basic, translational and clinical cancer research professionals.
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PRELIMINARY PROGRAM
Working titles shown. Final titles will be announced.

Tuesday, December 4, 2012


EDUCATIONAL SESSIONS

An update on advances in the technologies available for translational research. Sessions are to provide people with a better understanding of the talks they hear using the techniques described. They also provide researchers with a guide to the techniques they should be considering for their studies.


The Practical Use of Molecular Profiling
Moderator: Peter M. Ravdin, MD, PhD
UT Health Science Center San Antonio
San Antonio, TX

In treatment evaluation and treatment planning for premalignant disease and in situ cancers
Lawrence J. Solin, MD, FACR, FASTRO
Albert Einstein Medical Center
Philadelphia, PA

The practical use of molecular profiling: The view of a medical oncologist
Antonio C. Wolff, MD
Johns Hopkins Kimmel Cancer Center
Baltimore, MD

Use of genomic tests in routine practice and clinical research in metastatic breast cancer
Lajos Pusztai, MD, DPHIL
UT MD Anderson Cancer Center
Houston, TX

Clinical Trial Designs
Moderator: Susan G. Hilsenbeck, PhD
Baylor College of Medicine
Houston, TX

What agents should go into trials?
Angela DeMichele, MD, MSCE
University of Pennsylvania Perelman School of Medicine
Philadelphia, PA

Endpoints
Clifford A. Hudis, MD
Memorial Sloan-Kettering Cancer Center
New York, NY

Early phase trials
Susan G. Hilsenbeck, PhD
Baylor College of Medicine
Houston, TX

Randomized clinical trial designs: Still important
Sally Hunsberger, PhD
National Cancer Institute
Rockville, MD

Controversies in the Surgical Management of Breast Cancer
Moderator: Ismail Jatoi, MD, PhD, FACS
UT Health Science Center San Antonio
San Antonio, TX

Sentinel node biopsy in breast cancer: Before or after neoadjuvant chemotherapy
Eleftherios Mamounas, MD
Aultman Hospital
Canton, OH

Early versus delayed breast reconstruction
Andrea L. Pusic, MD, MHS, FRCSC
Memorial Sloan-Kettering Cancer Center
New York, NY

The role of MRI in management of primary breast cancer
Ismail Jatoi, MD, PhD, FACS
UT Health Science Center San Antonio
San Antonio, TX

Navigating the Obstacles of Survivorship
Moderator: Susan W. Rafte
Pink Ribbons Project
Houston, TX

Sexuality issues and answers for breast cancer survivors
Michael Krychman, MD
The Southern California Center for Sexual Health and Survivorship
Newport Beach, CA

Cognitive changes and breast cancer treatments
Patricia A. Ganz, MD
University of California, Los Angeles
Los Angeles, CA

Radiation risk, secondary primaries and serious late complication issues for breast cancer survivors
Jonine L. Bernstein, PhD
Memorial Sloan-Kettering Cancer Center
New York, NY

Her2-Positive Breast Cancer
Moderator: Eric P. Winer, MD
Dana-Farber Cancer Institute
Boston, MA

Karen Gelmon, MD
BC Cancer Agency
Vancouver, CANADA

Nancy U. Lin, MD
Dana-Farber Cancer Institute
Boston, MA

Mothaffar Rimawi, MD
Baylor College of Medicine
Houston, TX

Inflammation and Breast Cancer
Moderator: Charlotte Kuperwasser, PhD
Tufts University School of Medicine
Boston, MA

John Condeelis, PhD
Albert Einstein College of Medicine
Bronx, NY

Morag Park, PhD
McGill University
Montreal, CANADA

Links between inflammation, breast cancer and obesity
Charlotte Kuperwasser, PhD
Tufts University School of Medicine
Boston, MA

Tumor Dormancy and Late Recurrences
Moderator: George W. Sledge, Jr, MD
Indiana University Simon Cancer Center
Indianapolis, IN

Lewis A. Chodosh, MD, PhD
Pereleman School of Medicine
University of Pennsylvania
Philadelphia, PA

Ann F. Chambers, PhD
London Regional Cancer Program
London, CANADA

George W. Sledge, Jr, MD
Indiana University Simon Cancer Center
Indianapolis, IN

Biology of Triple-Negative Breast Cancer
Moderator: Nicholas Turner, MD
Royal Marsden Hospital
London, UNITED KINGDOM

Trey Westbrook, PhD
Baylor College of Medicine
Houston, TX

Jennifer A. Pietenpol, PhD
Vanderbilt University School of Medicine
Nashville, TN

The clonal and mutational evolution of primary triple negative breast cancers
Samuel Aparicio, PhD
University of British Columbia
Vancouver, CANADA

Mammary Cell Lineages and Breast Cancer Subtypes
Moderator: Michael T. Lewis, PhD, BS
Baylor College of Medicine
Houston, TX

Connie Eaves, PhD
University of British Columbia
Vancouver, CANADA

Cédric Blanpain, MD, PhD
Welbio, Interdisciplinary Research Institute
Bruxelles, BELGIUM

Understanding human cancer with single cell genetics
Nicholas E. Navin, PhD
UT MD Anderson Cancer Center
Houston, TX



AWARD LECTURES

Exhibit Hall D

AACR Outstanding Investigator Award for Breast Cancer Research, funded by Susan G. Komen for the Cure®

Speaker and Title TBA


Susan G. Komen for the Cure Brinker Awards for Scientific Distinction Lectures

Speakers and Titles TBA


AACR Distinguished Lectureship in Breast Cancer Research

Mina J. Bissell, PhD
Lawrence Berkeley National Laboratory
Berkeley, CA


William L. McGuire Memorial Lecture

Gabriel N. Hortobagyi, MD
UT MD Anderson Cancer Center
Houston, TX



PLENARY LECTURES



Exhibit Hall D

Paracrine Interactions of Epithelial Cells
Prof. Cathrin Brisken, MD, PhD
Ecole Polytechnique Fédérale de Lausanne
Lausanne, SWITZERLAND

Estrogen Receptor Cistrome: Implications for Breast Cancer
Jason S. Carroll, PhD
Cancer Research UK, University of Cambridge
Cambridge, UNITED KINGDOM

Radiation Therapy
John Yarnold, MD
Institute of Cancer Research
Sutton, UNITED KINGDOM



MINI-SYMPOSIA

Exhibit Hall D
Breast Density: Mechanisms and Clinical Implications
Moderator: Melissa Bondy, PhD
Baylor College of Medicine
Houston, TX

Biological basis of breast density and cancer risk
Thea D. Tlsty, PhD
University of California, San Francisco
San Francisco, CA

Clinical
Norman Boyd, MD, DSC
Ontario Cancer Institute
Toronto, CANADA

Genetics and epidemiology
Celine M. Vachon, PhD
Mayo Clinic College of Medicine
Rochester, MN

Snp’s - Germline Polymorphisms in Breast Cancer Susceptibility and Treatment Toxicity
Moderator: Laura J. van ’t Veer, PhD
University of California, San Francisco
San Francisco, CA

Susceptibility
Douglas Easton, PhD
University of Cambridge
Cambridge, UNITED KINGDOM

Toxicity
Bryan P. Schneider, MD, PhD
Indiana University School of Medince
Indianapolis, IN

Identifying the real promise of genomic medicine
James P. Evans, MD, PhD
University of North Carolina at Chapel Hill
Chapel Hill, NC

The mTOR pathway: Role in Metabolism and as a Therapeutic Target Moderator: Carlos L. Arteaga, MD
Vanderbilt-Ingram Cancer Center
Vanderbilt University

Targeting PI3K
Lewis Cantley, PhD
Beth Israel Deaconess Medical Center
Boston, MA

Translating regulation of mTOR and protein synthesis to the clinic for advanced breast cancer
Robert Schneider, PhD
NYU School of Medicine
New York, NY

Clinical development of mTOR inhibitors
Fabrice André, MD, PhD
Gustave Roussy Institute
Villejuif, FRANCE



THE YEAR IN REVIEW
Saturday, December 8, 2012


Exhibit Hall D

Moderator: C. Kent Osborne, MD
Baylor College of Medicine
Houston, TX

Advances in basic breast cancer research
Jeffrey M. Rosen, PhD
Baylor College of Medicine
Houston, TX

Discoveries in translational breast cancer research in 2012
Douglas Yee, MD
University of Minnesota
Minneapolis, MN

Adjuvant and neoadjuvant
Kathy D. Miller, MD
Indiana University School of Medicine
Indianapolis, IN

Metastatic
Stephen Johnston, MA, PhD, FRCP
Royal Marsden Hospital
London, UNITED KINGDOM



BASIC SCIENCE FORUMS



Ballroom B

Molecular Imaging of Breast Cancer: Visualizing In Vivo Breast Cancer Biology
Moderator: David A. Mankoff, MD, PhD
University of Washington Medical Center
Seattle, WA

Molecular imaging to characterize breast cancer models
Lewis A. Chodosh, MD, PhD
Pereleman School of Medicine
University of Pennsylvania
Philadelphia, PA

Molecular imaging for breast cancer patients
David A. Mankoff, MD, PhD
University of Washington Medical Center
Seattle, WA

Metastasis – Niches
Moderator: Yibin Kang, PhD
Princeton University
Princeton, NJ

Cancer stem cells interactions with their niche determine formation of breast cancer metastasis
Joerg Huelsken, PhD
Federal Technical University Lausanne
Lausanne, SWITZERLAND

Tumor-stromal interactions in bone metastasis
Yibin Kang, PhD
Princeton University
Princeton, NJ

Epigenetics in Molecular Medicine
Moderator: Nancy E. Davidson, MD
University of Pittsburgh Cancer Institute
Pittsburgh, PA

Epigenetics and cancer
Stephen B. Baylin, MD
Johns Hopkins University School of Medicine
Baltimore, MD

Epigenetic origins of luminal breast cancer
Tim Hui-Ming Huang, PhD
UT Health Science Center San Antonio
San Antonio, TX



CLINICAL SCIENCE FORUM

Ballroom A

Treatment on the Edges: Discordance Between Stage and Biology
Moderator: Kathy S. Albain, MD, FACP
Loyola University Chicago Stritch School of Medicine
Maywood, IL

Bad stage, but good biology
Kathy S. Albain, MD, FACP
Loyola University Chicago Stritch School of Medicine
Maywood, IL

Low stage…but adverse biology
Martine J. Piccart, MD, PhD
Jules Bordet Institute
Brussels, BELGIUM

4 Dec - 8 Dec 2012
San Antonio
United States of America
meeting website