Immunoreceptors


+ show speakers and program
Sunday,
July 8, 2012
4:00PM – 9:00AM Conference Registration
6:00PM – 7:00 PM FASEB Opening Reception
7:00PM – 8:30 PM Dinner
8:45PM – 10:00PM Keynote: Max Cooper, Emory University
Evolution of adaptive immunity
Monday,
July 9, 2012
7:30AM – 9:00AM Breakfast
Session 1:
9:00AM – 12:15PM
Evolution of Immunoreceptors
Session Chair: Erin Adams, University of Chicago
9:00AM – 9:15AM Welcome from FASEB
9:15AM - 9:45AM Roy Mariuzza, University of Maryland
Structural Insights into the Evolution of Adaptive Immunity
This activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.
9:45AM –10:15AM Erin Adams, University of Chicago
T cell receptor recognition of lipid antigens presented by CD1
molecules
10:15AM – 10:30 AM Short Talk Selected From Submitted Abstracts
10:30AM – 11:00AM Group photo & FASEB Sponsored Coffee Break
11:00AM – 11:30AM Randall Davis, University of Alabama at Birmingham
Biological Role of FCRL Molecules
11:30AM – 12:00PM Peter Parham, Stanford University
Co-evolution of variable NK-cell receptors with polymorphic MHC
Class I ligands
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM Lunch
Free Afternoon
4:00PM – 6:00PM Poster Session 1
6:00PM – 7:00PM Dinner
Session 2:
7:00PM – 9:45PM
Structure and Function of Immunoreceptors I
Session Chair: Jenny Woof, University of Dundee
7:00PM - 7:30PM Jenny Woof, University of Dundee
Immunoglobulin functional sites
7:30PM – 8:00PM Michelle Krogsgaard, New York University
Biophysical thresholds for T-cell recognition of self-ligands
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Brian Sutton, King's College London
New insights into the structure of IgE and its interaction with FcRI
9:15PM – 9:45PM Marion H. Brown, University of Oxford
Interactions of leukocyte surface receptors
Tuesday,
July 10, 2012
7:30AM – 9:00AM Breakfast
Session 3
9:00AM – 12:15PM
Structure and Function of Immunoreceptors II
Session Chair: Peter Sun, NIAID, NIH
This activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.
9:00AM - 9:30AM Peter Sun, NIAID, NIH
Insights from structures of Fc receptors and pentraxins
9:30PM –10:00AM K. Christopher Garcia, Stanford University
Understanding immunoreceptor recognition and activation
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Hiromi Kubagawa, University of Alabama at Birmingham
The elusive IgM receptor
11:15PM – 12:00PM Cheng Zhu, Georgia Institute of Technology
Kinetic analysis of molecular interactions at the interface of T cell
and antigen presenting cell
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM Lunch
Free Afternoon
4:00PM – 6:00PM Poster Session 2
6:00PM – 7:00PM Dinner
Session 4:
7:00PM – 9:45PM
The Immunological Synapse
Session Chair: Mike Dustin, New York University School of
Medicine
7:00PM - 7:30PM Mike Dustin, New York School University School of Medicine
Role of immunoreceptor targeted microvesicles in coordinating the
immune response
7:30PM – 8:00PM Stephen Bunnell, Tufts University
Scaffolding interactions integrating TCR-induced microclusters with
cytoskeletal systems
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Gillian Griffiths, University of Cambridge
Control of secretion at the immunological synapse
9:15PM – 9:45PM Mark Davis, Howard Hughes Medical Institute
Molecular movement at the T cell: antigen presenting cell synapse
Wednesday,
July 11, 2012
This activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.
7:30AM – 9:00AM Breakfast
Session 5
9:00AM – 12:15PM
Immunoreceptor Dynamics I
Session Chair: David Holowka, Cornell University
9:00AM - 9:30AM Marek Cebecauer, J. Heyrovsky Institute, Prague
Spatio-temporal organisation of T cell signaling molecules
9:30PM –10:00AM Facundo Batista, CRUK London Research Institute
Early events in B cell activation: from single molecule to living
tissue
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Ian Dransfield, University of Edinburgh
Mechanisms underlying regulation of FcRIIa function on myeloid
cells
11:15PM – 12:00PM Diane Lidke, University of New Mexico
Single molecule imaging to quantify FcRI signaling dynamics
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM
1:15PM – 2:15PM
Lunch
Meet the Expert
Free Afternoon
4:00PM – 6:00PM Poster Session 3
6:00PM – 7:00PM Dinner
Session 6:
7:00PM – 9:45PM
Immunoreceptors in Disease
Mark Hogarth, Burnett Institute, Melbourne
7:00PM - 7:30PM Marjolein van Egmond, VU Med. Center, Amsterdam
The human IgA Fc receptor FcRI; for better or worse?
7:30PM – 8:00PM Tanya Mayadas, Harvard University
Interplay of neutrophil FcRs and integrin Mac-1 in autoimmunemediated
inflammation
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Mark Hogarth, Burnett Institute, Melbourne
The interplay between immunoreceptors and their ligands in
disease development and resistance
This activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.
9:15PM – 9:45PM Richard Blumberg, Brigham's amd Women's Hospital, Boston
Multiple roles of FcRn in health and disease
Thursday,
July 12, 2012
7:30AM – 9:00AM Breakfast
Session 7
9:00AM – 12:15PM
Regulation of Responses
John Cambier, University of Colorado
9:00AM - 9:30AM John Cambier, University of Colorado
Signaling mechanisms that maintain anergy, and fail in
autoimmunity
9:30PM –10:00AM Renato Monteiro, Paris Diderot Medical School
Inhibitory ITAM-bearing Fc receptors in inflammation control
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Robert Rickert, Sanford-Burnham Medical Research Institute, La
Jolla
The PI3-kinase pathway in normal and aberrant B cell
differentiation
11:15PM – 12:00PM Jürgen Wienands, University of Göttingen
BCR activation signals for naive and class-switched memory B cells
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 12:45PM Business Meeting
12:45PM – 1:45PM Lunch
Free Afternoon
1:00PM – 6:00PM Optional Organized Group Activity
4:00PM – 6:00PM Poster Session 4
6:00PM – 7:00PM Dinner
Session 8:
7:00PM – 9:45PM
Immunoreceptor Dynamics II
Sally Ward, UT Southwestern Medical Center, Dallas
7:00PM - 7:30PM David Holowka, Cornell University
Signaling Downstream of FcRI: Ca2+ in Mast Cell Functions
7:30PM – 8:00PM Sally Ward, UT Southwestern Medical Center, Dallas
Targeting FcRn for therapy: from single molecules to in vivo studies
This activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Attila Mocsai, Semmelweis University, Budapest
Tyrosine kinase pathways during neutrophil activation and
migration
9:15PM – 9:45PM Ellis Reinherz, Dana-Farber Cancer Institute
Structural and force considerations in TCR engagement
Friday,
July 13, 2012
7:30AM – 8:30AM Breakfast
Session 9
8:30AM – 11:30PM
Therapeutic applications
Jeanette Leusen, University Medical Center Utrecht
8:30AM - 9:00AM Menno van Lookeren Campagne, Genetech Inc, San Francisco
Complement receptors in inflammation
9:00AM – 9:30AM Carl H June, University of Pennsylvania
Chimeric antigen receptors in the clinic: challenges and
opportunities
9:30AM – 9:45AM Short Talk Selected From Submitted Abstracts
9:45AM – 10:00AM Break
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM Jeanette Leusen, University Medical Center Utrecht
IgA as a new therapeutic antibody
10:45AM – 11:15PM Thomas Valerius, Christian-Albrechts University, Kiel
Improving effector mechanisms in EGFR antibody therapy
11:15AM – 11:30AM Closing Comments
11:30AM Departures

8 Jul - 13 Jul 2012

Snowmass Village
United States of America
meeting website