Folic acid, vitamin B12 and one-carbon metabolism


+ show speakers and program
Sunday, July 22, 2012
4:00p.m. – 9:00p.m. Conference Registration
6:00p.m. – 7:30 p.m. FASEB Opening Reception
7:30p.m. – 8:30 p.m. Dinner
8:30p.m. – 8:45 p.m. Welcome from FASEB
Session 1 8:45p.m – 10:15 p.m. Workshop: New Developments in
Metabolomics and Receptor Biology
Session Chair: Steven S. Gross, Weill
Cornell Medical College
8:45p.m.-9:15p.m. Steven S. Gross, Weill
Cornell Medical College
“Global metabolite profiling as a tool for
untargeted discovery of metabolites and
pathways involved in folate-responsive birth
defects”
9:15p.m.-9:45p.m. Maria Luz Martinez, CICbioGUNE
“Metabolomics approach in Non Alcoholic Fatty
Liver Disease (NAFLD)”
9:45p.m.-10:15p.m. Charles E. Dann, III, Indiana University
“Transcobalamin and its receptor”
Monday, July 23, 2012
7:30a.m. – 8:30a.m. Breakfast
Session 2 8:30a.m.-12:00p.m. Inborn Errors of Vitamin B12 Metabolism
Session Chair: Charles Venditti, NHGRI/NIH
This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
8:30a.m-9:00a.m. Charles Venditti, NHGRI/NIH
“Mouse Models and Gene Therapy
Approaches to Methylmalonic Aciduria”
9:00a.m.-9:30a.m. *Ruma Banerjee, Univ. Michigan
“Enzymology of L-Methylmalonyl-CoA
Mutase”
9:30a.m.-9:45a.m. Presentation selected from abstracts
9:45a.m.-10:15a.m. Group Photo and Coffee Break
10:15a.m.– 10:45a.m. *Irini Manoli, NHGRI/NIH
“Phenotypes and pathophysiology of
disorders in the intracellular cobalamin
metabolism pathway”
10:45a.m. – 11:15a.m. Sergey Fedosov, University of Aarhus
“Computational model of B12 deficiency and
implications for diagnostics"
11:15a.m. – 11:30a.m. Presentation selected from abstracts
11:30a.m. – 11:45a.m. Presentation selected from abstracts
11:45a.m. – 12:00p.m. Presentation selected from abstracts
12:00p.m. – 1:30p.m. Lunch (Trainee Lunch 1 with Session
Chairs)
Session 3: 2:00p.m. – 5:20p.m. Nutritional Modifers of Cognition and
Adult Diseases
Session Chair: Kimford J. Meador, Emory
University
2:00p.m.-2:30p.m. Kimford J. Meador, Emory University
“Periconceptional folate and cognitive
outcomes in children of mothers with
epilepsy.”
2:30p.m.-3:00p.m. *Christy C. Tangney, Rush University
Medical Center
“Vitamin B12, cognition, and brain MRI
measures”
3:00p.m. – 3:15p.m. Presentation selected from abstracts
This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
3:15pm-3:35p.m. FASEB Sponsored Coffee Break
3:35p.m.-4:05p.m. *Almany K. Elshorbagy, University of
Alexandria, Egypt
“Dietary cysteine levels and obesity”
4:05p.m.-4:35p.m. Babak Hooshmand, Karolinksa Institute
“Homocysteine and holotranscobalamin and
risk for Alzheimer Disease”
4:35p.m.-4:50p.m. Presentation selected from abstracts
4:50p.m.-5:05p.m. Presentation selected from abstracts
5:05p.m.-5:20p.m. Presentation selected from abstracts
5:30p.m.-7:30p.m. Poster Session 1 (posters remain up for
2 days)
8:00p.m. Dinner
Tuesday, July 24, 2012
7:30a.m. – 8:30a.m. Breakfast
Session 4: 8:30a.m.-11:50a.m. Perturbations in One Carbon Metabolism
Session Chair: Sean Brosnan, Memorial
University
8:30a.m.-9:00a.m. Sean Brosnan, Memorial University
“Methyl balance-quantitative relationships
and perturbations”
9:00a.m.-9:30a.m. Hieronim Jakubowski, Univ. Med. Dentistry
of New Jersey
“Post-translational modification of one
carbon metabolism”
9:30a.m.-9:45a.m. Presentation selected from abstracts
9:45a.m. - 10:05a.m. FASEB Sponsored Coffee Break
10:05a.m.-10:35a.m. Sergey Krupenko, Medical University of So.
Carolina
“Mitochondrial folate metabolism”
This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
10:35a.m. – 11:05a.m. Dean Appling, The University of Texas at
Austin
"Mitochondrial formate production and
mammalian development"
11:05p.m. – 11:20a.m. Presentation selected from abstracts
11:20a.m. – 11:35a.m. Presentation selected from abstracts
11:35a.m. – 11:50a.m. Presentation selected from abstracts
12:00p.m.-1:30p.m. Lunch
1:30p.m.-6:30p.m. Free Time
7:30p.m.-8:30p.m. Dinner
Session 5: 8:45p.m.-10:15p.m. Issues in the Analysis of Biomarkers of
Folate, Hcy, Vitamins B6 and B12
Session Chair: Henk Blom, Free University
Amsterdam
8:45p.m. - 9:15p.m. Henk Blom, Free University Amsterdam
“Analysis issues of one carbon analytes”
9:15p.m. – 9:45p.m. *Christine Pfeiffer, Centers for Disease
Control and Prevention
“Analysis of B vitamins in NHANES:
Influence of demographic, life-style, socioeconomic,
and health factors.”
9:45p.m. – 10:15p.m. *Regan Bailey, NIH
“Impact and measurement of unmetabolized
folic acid in fortified populations”
Wednesday, July 25, 2012
7:30a.m. – 8:30a.m. Breakfast
Session 6 8:30a.m.-11:50a.m. Workshop: Consequences of Worldwide
Dietary Deficiencies of Cobalamin and/or
Folates
Session Chair: Sally P.Stabler, University of
Colorado-Denver
8:30a.m-9:00a.m. *Sally P. Stabler, Univ. Colorado-Denver
“Environmental and Food Sources of
Naturally Occuring Cobalamin Analogues”
This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
9:00a.m.-9:30a.m. Asok Antony, Indiana University School of
Medicine
“Activation of a homocysteine-responsive
posttranscriptional RNA operon: Stumbling
into Virology”
9:30a.m. – 9:45a.m. Presentation selected from abstracts
9:45a.m.-10:05a.m. FASEB Sponsored Coffee Break
10:05a.m. – 10:35a.m. *Daphna Dor, University of California,
Davis
“Neurodevelopment in the vitamin B12
deficient infant”
10:35a.m. – 11:05a.m. *Lynn Bailey, University of Georgia
“Folate Intake and Status in the US”
11:05a.m. – 11:20a.m. Presentation selected from abstracts
11:20a.m. – 11:35a.m. Presentation selected from abstracts
11:35a.m. – 11:50a.m. Presentation selected from abstracts
12:00p.m.-1:30p.m. Lunch
Session 7: 2:00p.m. – 5:05p.m Methylation and Epigenetic Regulation of
Disease
Session Chair: Angela Devlin, University of
British Columbia
2:00p.m. - 2:30p.m. *Angela Devlin, UBC
“Prenatal exposure to maternal depressed
mood and the MTHFR C677T variant
affects SLC6A4 methylation in infants at
birth”
2:30p.m. – 3:00p.m. *Marie Caudill, Cornell University
“Varied maternal choline intake in humans
alters metabolic and epigenetic marks”
3:00p.m. – 3:15p.m. Presentation selected from abstracts
3:15p.m. – 3:35p.m. FASEB Sponsored Coffee Break
This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
3:35p.m. – 4:05p.m. Shekhar Mayanil, Northwestern University
“Folic acid remodels chromatin during
neural tube closure”
4:05p.m. – 4:35p.m. Warren D. Kruger, Fox Chase Cancer
Center
“Hyperhomocysteinemia, S-adenosylhomocysteine
accumulation and
epigenetics”
4:35p.m. - 4:50p.m. Presentation selected from abstracts
4:50p.m. - 5:05p.m. Presentation selected from abstracts
5:15p.m. -7:15p.m. Poster Session 2 (posters remain for 2
days)
8:00p.m. Dinner
Thursday, July 26, 2012
7:30a.m. – 8:30a.m. Breakfast
8:30a.m.-12:00p.m. Free Time
12:00p.m.-1:30p.m. Lunch (Trainee Lunch 2 with Session
Chairs)
Session 8: 2:00p.m.-5:20p.m. Inherited Disorders of One Carbon
Metabolism
Session Chair: Rima Rozen, McGill
University School of Medicine
2:00p.m.-2:30p.m. *Rima Rozen, McGill University School of
Medicine
“Dietary influences on cardiac development
in genetically modified mice “
2:30p.m.-3:00p.m. I. David Goldman, Einstein Medical College
"The role of the proton-coupled folate
transporter in folate homeostasis; loss-offunction
in hereditary folate malabsorption"
3:00p.m. - 3:15p.m. Presentation selected from abstracts
This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
3:15p.m. – 3:35p.m. FASEB Sponsored Coffee Break
3:35p.m.-4:05p.m. Robert Cabrera, University of Texas
“The impact of the proton-coupled folate
transporter on tissue uptake of folates”
4:05p.m.-4:35p.m. Sergey Krupenko, Medical University of So.
Carolina
“Mitochondrial folate metabolism”
4:35p.m.-5:05p.m. Fernando Scaglia, Baylor College of
Medicine
“Mitochondrial disorders, cerebral folate
deficiency, and nutritional interventions “
5:05p.m.-5:20p.m. Presentation selected from abstracts
5:45p.m.-7:00p.m. Business Meeting and Awarding of Travel
Fellowships
8:00p.m. Dinner
Friday, July 27, 2012
7:30a.m. – 8:30a.m. Breakfast
Session 9: 8:30a.m.-11:35a.m. Genomic Approaches to One Carbon
Metabolism
Session Chair: Steve Whitehead, University
of Pennsylvania School of Medicine
8:30a.m.-9:00a.m. Steve Whitehead, University of
Pennsylvania School of Medicine
“Is there a dark side to folate metabolism?:
the relationship between folate-related
genetic and phenotypic variables and lung
cancer”
9:00a.m.-9:30a.m. Anne Molloy, Trinity University
“One-carbon metabolic profiling: preliminary
GWAS results in a genetically
homogeneous young adult population”
9:30a.m. - 9:45a.m. Presentation selected from abstracts
9:45a.m. - 10:00a.m. Presentation selected from abstracts
This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
10:00a.m. - 10:20a.m. FASEB Sponsored Coffee Break
10:20a.m. – 10:35a.m. Presentation selected from abstracts
10:35a.m. - 11:05a.m. Diego Ingrosso, Second Univ. of Naples
“Folates, macromolecule methylation and
sulfur compounds: dangerous liaisons and
therapeutical opportunities”
11:05a.m.-11:35a.m. Patrick J. Stover, Cornell University
“B-Vitamin-Genome Interactions: The Role
of Nuclear and Mitochondrial Metabolic
Compartmentation in Gene Expression and
Genome Stability.”
11:35a.m.-12:15p.m. Closing Comments and Discussions
Departure

22 Jul - 27 Jul 2012

Kolymvari Chania
Greece
meeting website