Liver Biology: Fundamental Mechanisms & Translational Applications


Liver Biology: Fundamental Mechanisms & Translational
Applications
+ show speakers and program
Co-Organizers:
Name
Linda E. Greenbaum,
Thomas Jefferson University, Philadelphia, PA
Name
Jessica Zucman-Rossi
University of Paris Descartes
INSERM U674, Paris, France
Sunday,
July 29, 2012
4:00PM – 9:00AM Conference Registration

6:00PM – 7:00 PM FASEB Opening Reception

7:00PM – 8:30 PM Dinner

8:45PM – 10:00PM Michael G. Rosenfeld
“Title of talk” (OPTIONAL)
Monday,
July 30, 2012
7:30AM – 9:00AM Breakfast

Session 1:
9:00AM – 12:30PM
Liver development and mechanisms of disease
Josh Friedman, Children’s Hospital, Philadelphia and Valerie
Gouon-Evans, Mount Sinai School of Medicine

9:00AM – 9:15AM Welcome from FASEBThis activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.

9:15AM - 9:45AM Frederick Lemaigre, University Catholique de Louvein
“Transcriptional regulation of bile duct morphogenesis”
9:45AM –10:15AM Valerie Gouon-Evans, Mount Sinai School of Medicine
“Endothelial cells in liver development and regeneration” s

10:15AM – 10:30 AM Short Talk Selected From Submitted Abstracts
10:30AM – 11:00AM Group photo & FASEB Sponsored Coffee Break
11:00AM – 11:30AM Speaker 3, Christine Perret, Institute Cochin
“The role of wnt/beta-catenin signaling in liver physiopathology”

11:30AM – 12:00PM Speaker 4, Joshua Friedman, Children’s Hospital Philadelphia
“Microrna in liver development and cholestatic disease”
12:00PM – 12:30PM Didier Stainier, University of California, San Francisco
“Hepatic Duct Development in Zebrafish”
12:30PM – 1:30PM Lunch

Free Afternoon
4:00PM – 6:00PM
6:00PM – 7:00PM Dinner

Session 2:
7:00PM – 10:15 PM
Regulation of hepatobiliary gene expression in health and
disease
Chairs: Linda Greenbaum, Thomas Jefferson University, Antonello
Pietrangelo, University of Modena and Reggio

7:00PM - 7:30PM Speaker 1, Jacquelyn Maher, University of California, San
Francisco
“ER stress in fatty liver disease”
7:30PM – 8:00PM Christian Trautwein, University of Aachen
“Title of talk”

8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Speaker 3, Antonello Pietrangelo, University of Modena and Reggio
The transcriptional control of Hepcidin, the iron homone, at the
interface of innate immunity and metabolic adaptation”

9:15PM – 9:45PM Speaker 4, Sophie Lotersztajn, INSERM Paris
“Cannabinoids are hepatoprotective in liver fibrosis”
9:45PM – 10:15 PM Chantal Desdouets, INSERM Paris
“Insulin signaling regulates polyploidy in liver cells”This activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.
Tuesday,
July 31, 2012
7:30AM – 9:00AM Breakfast

Session 3
9:00AM – 12:15PM
Liver Growth and Regeneration
Jeff Albrecht, Hennepin County Medical Center, Satdarshan (Paul)
Monga, University of Pittsburgh

9:00AM - 9:30AM Speaker 1, George Michalopoulos, University of Pittsburgh
“Regulation of beginning and end of liver regeneration”

9:30PM –10:00AM Speaker 2, Michelle Barton, Baylor College of Medicine
“Gain and Loss of Function for p53 during Liver
Regeneration”
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts

10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Speaker 3, Eli Pikarsky, Hebrew University
“Regenerotrophy vs. regeneroplasia-alternative modes of
regeneration of liver mass”

11:15PM – 12:00PM Speaker 4, Holger Willenbring, University of California, San
Francisco
“Origin and potency of liver stem cells”
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM
1:15PM – 2:15PM
Lunch
Meet the Expert

Free Afternoon
4:00PM – 6:00PM Poster Session 1
6:00PM – 7:00PM Dinner

Session 4:
7:00PM – 10:15PM
Liver Metabolism in health and disease
Mark Czaja, Einstein College of Medicine, Frank Anania, Emory
University
7:00PM - 7:30PM Speaker 1, Mark Czaja, Einstein College of Medicine
“Autophagy: lipid regulator in steatosis and cell death”
7:30PM – 8:00PM Speaker 2, David Moore, Baylor College of Medicine
“Title of talk”

8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts This activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.

8:45PM – 9:15PM Speaker 3, Frank Anania, Emory University
“Title of talk
9:15PM – 9:45PM Speaker 4, Jeffrey Albrecht, Hennepin County Medical Center
“Coordination of cell cycle control and metabolism in the liver”
9:45PM – 10:15PM Speaker 5, Satdarshan (Paul) Monga, University of Pittsburgh
Wednesday,
August 1, 2012
7:30AM – 9:00AM Breakfast

Session 5
9:00AM – 12:30PM
Angiogenesis, Injury and Hepatic Fibrosis
Wajahat Mehal, Yale University, Laurie DeLeve, University of
Southern California

9:00AM - 9:30AM Speaker 1, Rebecca G. Wells, University of Pennsylvania
“Title of talk

9:30PM –10:00AM Speaker 2, Laurie DeLeve, University of Southern California
“Title of talk
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts

10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Speaker 3, Wajahat Mehal, Yale University
Inflammasome components: linking inflammtion and fibrogenesis”

11:15PM – 12:00PM Speaker 4, Anna Mae Diehl, Duke University
“Title of talk”
12:00PM – 12:30PM Speaker 5, Scott Friedman, Mount Sinai School of Medicine
“Elucidating Stellate Cell Biology through in Vivo Ablation and Cell‐Specific
Gene Knockouts”

12:30PM – 1:30PM Lunch

Free Afternoon
4:00PM – 6:00PM Poster Session 2
6:00PM – 7:00PM Dinner

Session 6:
7:00PM – 9:45PM
Liver Cancer
Erik Knudsen, Thomas Jefferson University, Jessica ZucmanRossi, INSERM Paris
7:00PM - 7:30PM Speaker 1, Snorri Thorgeirsson, NIH
“Stem Cells and Cancer: A Fatal Attraction
7:30PM – 8:00PM Speaker 2, C. Bart Rountree, Hershey Medical Center
“Liver cancer: understanding mechanisms of metastasis and
disease resistanceThis activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.

8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Speaker 3, Erik Knudsen, Thomas Jefferson University
“Title of talk”
9:15PM – 9:45PM Speaker 4, Randy L. Johnson, M.D. Anderson Cancer Center
“Hippo signaling in liver growth and disease”

9:45PM – 10:15PM Speaker 5, Klaus Kaestner, University of Pennsylvania
“Sexual dimorphism of liver cancer risk-it all depends on Fox”
Thursday,
August 2, 2012
7:30AM – 9:00AM Breakfast

Session 7
9:00AM – 12:15PM
Liver Stem cells
Ben Stanger, University of Pennsylvania, Frederic Lemaigre,
University Catholique de Louvain

9:00AM - 9:30AM Speaker 1, Keigo Machida, University of Southern California
Tumor-initiating stem cell and oncogenic signaling involving Nanog

9:30PM –10:00AM Speaker 2, Stephen Duncan, Medical College of Wisconsin
“Modeling human hepatocyte differentiation and disease using
pluripotent stem cells
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts

10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Speaker 3, Ben Stanger, University of Pennsylvania
“Title of talk”
11:15PM – 12:00PM Speaker 4, George Yeoh, University of Western Australia
“Inflammatory factors that induce growth, differentiation and
transformation of liver progenitor cells”

12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 12:45PM Business Meeting
12:45PM – 1:45PM Lunch
Free Afternoon
1:00PM – 6:00PM Optional Organized Group Activity
4:00PM – 6:00PM
6:00PM – 7:00PM DinnerThis activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.

Session 8:
7:00PM – 10:30PM
Hepatocyte, stem cell transplantation, tissue engineering I
Ira Fox, University of Pittsburgh, Linda Griffith, MIT
7:00PM - 7:30PM Speaker 1, Markus Grompe, Oregon Health and Sciences
University
“Title of talk
7:30PM – 8:00PM Speaker 2, Sangeeta Bhatia, MIT
“Title of talk

8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Speaker 3, Linda Griffith, MIT
“Title of talk
9:15PM – 9:45PM Speaker 4, Ira Fox, University of Pittsburgh
“Title of talk”
9:45PM-10:15PM Speaker 5, Michael Oertel, Einstein College of Medicine
Generating functional liver tissue through fetal liver stem/progenitor
cell transplantation

10:15PM-10:30PM Closing comments
Friday,
August 3, 2012
7:30AM – 8:30AM Breakfast

11:30AM Departures
Boxed Lunches Available

29 Jul - 3 Aug 2012
snowmass village
United States of America
meeting website