Protein Phosphatases

2012 FASEB Science Research Conferences
Protein Phosphatases
+ show speakers and program
Co-Organizers:
Zhong-Yin Zhang
Indiana University School of Medicine
Indianapolis, Indiana
William C. Hahn
Dana-Farber Cancer Institute
Boston, Massachusetts
Sunday, July 15, 2012
4:00PM – 9:00PM Conference Registration
6:00PM – 7:00PM FASEB Opening Reception
7:00PM – 8:30PM Dinner
8:45PM – 10:00PM Keynote Lecture
“Protien Tyrosine Phosphatases: New Functions in Cell
Signaling and Metabolism”
Jack E. Dixon
UCSD & HHMI
Monday, July 16, 2012
7:30AM – 9:00AM Breakfast
Session 1: 9:00AM – 12:15PM Structure and Function of Protein Phosphatases
Session Chair: Brian Wadzinski, Vanderbilt University
Medical Center
9:00AM – 9:15AM Welcome from FASEB and Organizers
9:15AM - 9:45AM Ben Neel
Ontario Cancer Institute This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
“Shp2 in health and disease”
9:45AM –10:15AM Jessie Zhang
University of Texas, Austin
“Unmask the “CTD” code for transcription regulation”
10:15AM – 10:30AM Short Talk Selected From Submitted Abstracts
10:30AM – 11:00AM Group photo & FASEB Sponsored Coffee Break
11:00AM – 11:30AM Brian Wadzinski
Vanderbilt University Medical Center
“Novel regulatory mechanisms for PP2A family
members, key regulators of the cell”
11:30AM – 12:00PM Wolfgang Peti
Brown University
“Using structure to define the function and selectivity of
phosphatases”
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM Lunch
Free Afternoon
4:00PM – 6:00PM Poster Session 1 – (odd numbers)
6:00PM – 7:00PM Dinner
Session 2: 7:00PM – 9:45PM Regulation and Targeting of Protein Phosphatases
Session Chair: Nunzio Bottini, La Jolla Institute for
Allergy and Immunology
7:00PM - 7:30PM David Brautigan
University of Virginia School of Medicine
“Protein Phosphatase-6 and E-cadherin”
7:30PM – 8:00PM Mathieu Bollen
University of Leuven, Belgium
“Function of PP1 at the mitotic exit”
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Nick Tonks
Cold Spring Harbor Laboratory
“Functional analysis of protein tyrosine phosphatases” This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
9:15PM – 9:45PM Nunzio Bottini
La Jolla Institute for Allergy and Immunology
“PTPN22 and autoimmunity”
Tuesday, July 17, 2012
7:30AM – 9:00AM Breakfast
Session 3: 9:00AM – 12:15PM Signaling Mechanisms by Protein Dephosphorylation
Session Chair: Catherine Pallen, University of British
Columbia

9:00AM - 9:30AM Catherine Pallen
University of British Columbia
“PTPa, Roles in Integrin- and Growth Factor-induced
Cell Movement”
9:30PM –10:00AM Ari Elson
The Weizmann Institute of Science
“PTPs in bone development and metabolism”
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Egon Ogris
Max F. Perutz Laboratories, Medical University of
Vienna
“Identification and characterization of PP2A substrates”

11:15PM – 11:45AM David Virshup
Duke-NUS, Singapore
“Redundant roles of PP2A in cell cycle control”
11:45AM – 12:00PM Short Talk Selected From Submitted Abstracts
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM Lunch
Free Afternoon
4:00PM – 5:00PM Poster Session 2 – (odd numbers)
5:00PM – 6:00PM “Meet the Experts/Speakers”
6:00PM – 7:00PM Dinner
Session 4: 7:00PM – 9:45PM Protein Phosphatases in Cancer I
Session Chair: Gen-Sheng Feng, UCSD
7:00PM - 7:30PM Richard Honkanen This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
University of South Alabama
“PP5/PPP5c an often overlooked ser/thr phosphatase
that is sensitive to okadiac acid and expressed in most,
if not all, human cells”
7:30PM –8:00PM Susann Brady-Kalnay
Case Western Reserve University
“Receptor Protein Tyrosine Phosphatase Cleavage: A
New Paradigm for Cancer Detection and Treatment”
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Lloyd Trotman
Cold Spring Harbor Laboratory
“The PTEN phosphatase network and prostate cancer
lethality”
9:15PM – 9:45PM Gen-Sheng Feng
UCSD
“The pro- and anti-oncogenic activities of Shp2”
Wednesday, July 18, 2012
7:30AM – 9:00AM Breakfast
Session 5: 9:00PM – 12:15PM New Frontiers in Protein Phosphatase Research
Session Chair: William Hahn, Dana-Farber Cancer Institute
9:00AM - 9:30AM William Hahn
Dana-Farber Cancer Institute
“Functional genomics of protein phosphatases”
9:30AM – 10:00AM Anne-Claude Gingras
Samuel Lunenfeld Institute, University of Toronto
“Substrate recognition by phosphatases”
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15AM Jing Zhang
Johns Hopkins University School of Medicine
“Spatiotemporal regulation of kinases and
phosphatases in living cells”
11:15AM – 11:45AM Dehua Pei
Ohio State University This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
“Substrate profiling of protein kinases and
phosphatases”
11:45AM – 12:00PM Short Talk Selected From Submitted Abstracts
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM Lunch
Free Afternoon
4:00PM – 6:00PM Poster Session 3 – (even numbers)
6:00PM – 7:00PM Dinner
Session 6: 7:00PM – 9:45PM Chemical Biology and Drug Discovery Targeting
Protein Phosphatases
Session Chair: John Lazo, University of Virginia
7:00PM - 7:30PM John Lazo
University of Virginia School of Medicine
“Targeting dual specificity phosphatases for anticancer
agents”
7:30PM – 8:00PM Paul Lombroso
Yale University
“Taking STEPs to improve cognitive function”
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Anne Bertolotti
MRC Laboratory of Molecular Biology, UK
“Selective inhibition of serine/threonine phosphatases”
9:15PM – 9:45PM Tzu-Ching Meng
Academia Sinica, Taiwan
“PTPs as novel therapeutic targets against ischemic
damage to the heart”
Thursday, July 19, 2012
7:30AM – 9:00AM Breakfast
Session 7: 9:00AM – 12:30PM Protein Phosphatases in Cancer II
Session Chair: Rosalie Sears, Oregon Health and
Sciences University
9:00AM - 9:30AM Rosalie Sears This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
Oregon Health and Sciences University
“PP2A regulation of c-Myc oncogenic activity”
9:30PM –10:00AM Jukka Westermarck
University of Turku, Finland
“Targeting inactivated PP2A for cancer therapy”
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15AM Michel Tremblay
McGill University
“Protein tyrosine phosphatases in the oncogenic
process”
11:15AM – 11:45AM Qi Zeng
Institute of Molecular and Cell Biology, Singapore
“PRL-3 phosphatase and cancer metastasis”
11:45AM – 12:00PM Short Talk Selected From Submitted Abstracts
12:00PM – 12:30PM Business Meeting
12:30PM – 1:30PM Lunch
Free Afternoon
1:00PM Optional Organized Group Activity
4:00PM – 5:00PM Poster Session 4 – (even numbers)
5:00PM – 6:00PM “Meet the Experts/Speakers”
6:00PM – 7:30PM Dinner
Session 8: 7:00PM – 9:45PM Protein Phosphatases in Metabolic Disorders
Session Chair: Kendra Bence, University of
Pennsylvania
7:00PM - 7:30PM Kendra Bence
University of Pennsylvania
“Novel roles for protein tyrosine phosphatases in
metabolism”
7:30PM – 8:00PM Tony Tiganis
Monash University, Australia
“PTPs and leptin resistance”
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:45PM Anna DePaoli-Roach This activity is not being planned in accordance with the ACCME Standards for Commercial
Support. AMA PRA Category 1 Credit(s)™ will not be offered.
Indiana University School of Medicine
“Protein Targeting to Glycogen (PTG) and Lafora
Disease”
8:45PM – 9:00PM Break
9:00PM – 9:45PM Keynote Lecture
“Control of Growth through the TOR pathway”
David Sabatini
Whitehead Institute for Biomedical Research
Friday, July 20, 2012
7:30AM – 8:30AM Breakfast
Session 9: 8:30AM – 12:15PM Protein Phosphatases in Development and Diseases
Session Chair: Maria Kontaridis, Beth Israel Deaconess
Medical Center/Harvard Medical School
8:30AM - 9:00AM Anton Bennett
Yale University
“Signaling by Dual-Specificity Protein Phosphatases in
Disease”
9:00AM – 9:30AM Jeroen den Hertog
Hubrecht Institute, the Netherlands
“Protein tyrosine phosphatases in zebrafish
development”
9:30AM – 9:45AM Short Talk Selected From Submitted Abstracts
9:45AM – 10:00AM FASEB Sponsored Coffee Break
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM Maria Kontaridis
Beth Israel Deaconess Medical Center/Harvard Medical
School
“Shp2 mutations and their effects on cardiovascular
function”
10:45AM – 11:15AM Dipanjan Chowdhury
Dana-Farber Cancer Institute
“Phosphoproteomic screen reveals a novel role for PP4
in the DNA damage response”
11:15AM – 11:30AM Closing Comments

11:30AM Departure
Boxed Lunches Available

15 Jul - 20 Jul 2012
snowmass village
United States of America
meeting website