Osteopontin Biology


FASEB Summer Research Conferences
Osteopontin Biolog
+ show speakers and program
Co-Organizers:
Marta Scatena,
University of Washington Seattle, WA
Masaki Noda,
University of
Tokyo, Japan
Vincent Castronovo,
University of Liege, Belgium
Sunday, August 5, 2012
2:00PM – 12:00AM Conference Registration
6:00PM – 7:00 PM FASEB Opening Reception
7:00PM – 8:30 PM Dinner

Monday, August 6, 2012
7:30AM – 8:30AM Breakfast
Session 1: 8:30AM – 12:15PM Osteopontin and Related Proteins: Structure and
functions
Chair: Larry W. Fisher
NIDCR/NIH Craniofacial and Skeletal Disease branch
8:30AM – 8:45AM Welcome
8:45AM - 9:10AM Speaker 1, Esben Sorensen, Protein Chemistry
Laboratory, Department of Molecular Biology, Aarhus
University, DK-8000 Aarhus, Denmark.
Title: "Posttranslational modification of
osteopontin" * This presenter has indicated a relationship which, in the context of their presentation, could be perceived by some as a real or apparent
conflict of interest but do not consider that it will influence their presentation. The disclosures have been reviewed and conflicts of interest
have been resolved by the Conference Organizer in accordance with the ACCME Standards for Commercial Support.
9:15AM –9:50AM Speaker 2, Zofia von Marschall, Craniofacial and
Skeletal Disease Branch, NIDCR/NIH
Title: “DSPP in health and disease: Insights into
trafficking of acidic proteins”
9:55 AM – 10:25AM Group photo & FASEB Sponsored Coffee Break
10:30AM – 10:55AM Speaker 3, Anne George, University Of Illinois at
Chicago, Chicago, IL
Title: “DPP mediated signaling events”
11:00AM – 11:25AM Speaker 4, Peter Rowe, The Kidney Institute, Kansas
University Medical Center, Kansas City, KS
Title: “The Chicken or the Egg: The SIBLINGs, PHEX
and FGF23 unscrambled”
11:30AM – 11:40AM Speaker 5, from abstracts
11:45AM – 11:55AM Speaker 6, from abstracts
12:00PM – 1:00PM Lunch
Free Afternoon
4:00PM – 6:00PM Poster Session 1
6:00PM – 7:00PM Dinner
Session 2: 7:00PM – 9:45PM Osteopontin and Related Proteins: Expression
regulation
Chair: Mohamed El-Tanani,Queens University, Center
for Cancer Research and Cell Biology, 97 Lisburn
Road, Belfast, BT9 7BL United Kingdom
7:00PM - 7:25PM Speaker 1, Paul C Kuo Department of Surgery, Dept
of Surgery, Loyola University Medical Center,
Maywood, IL
Title: “Osteopontin induces mesenchymal stem cell
production of TGF-beta”
7:30PM – 7:55PM Speaker 2, Gopal C Kundu National Center for Cell
Science, Pune, India
Title: "Role of Stroma and Tumor-derived
Osteopontin in Regulation of Tumor Progression and
Angiogenesis".
8:00PM – 8:15PM Break * This presenter has indicated a relationship which, in the context of their presentation, could be perceived by some as a real or apparent
conflict of interest but do not consider that it will influence their presentation. The disclosures have been reviewed and conflicts of interest
have been resolved by the Conference Organizer in accordance with the ACCME Standards for Commercial Support.
8:20PM – 8:45 Speaker 3, Paul Shore, University of Manchester
"Michael Smith Building”, Oxford Road, Manchester,
UK
Title: TBD
8:50PM – 9:15PM Speaker 4, Natalia Nieto Department of Medicine,
Division of Liver Diseases, Mount Sinai School of
Medicine, New York, New York
Title: “The OPN – HMGB1 axis and liver fibrosis”
9:20PM – 9:30PM Speaker 5, from abstracts
9:35PM – 9:45PM Speaker 6, from abstracts
Tuesday, August 7, 2012
7:30AM – 9:00AM Breakfast
Session 3: 9:00AM – 12:15PM Osteopontin and Related Proteins: Cancer
development and progression
Chair: Lalita R. Shevde-Samant, University of South
Alabama Cancer Research Institute Mobile, AL.
9:00AM - 9:25AM Speaker 1, Akeila Bellahcene, University of Liege,
GIGA-Cancer, Pathology Tour, Liege, 4000 Belgium”
Title: "Osteopontin targeting in cancer stem cells"
9:30AM –9:55AM Speaker 2, Lalita R. Shevde-Samant, University of
South Alabama Cancer Research Institute Mobile, AL.
Title: “The OPNing Act in Cancer”

10:00AM – 10:20AM FASEB Sponsored Coffee Break
10:25AM – 10:50AM Speaker 3, Hwyda Arafat Department of Surgery,
Jefferson Pancreatic, Biliary and Related Cancer
Center, Thomas Jefferson University, 1015 Walnut
Street, Philadelphia, PA
Title: “Osteopotnin-RANGTPase in Pancreatic Ductal
Adenocarcinoma”
10:55AM – 11:20AM Speaker 4, Neal S FEDARKO, Biology of Frailty
Program, Division of Geriatric Medicine and
Gerontology, Johns Hopkins University, Baltimore,
Maryland
Title: "Oteopontin and tumor associated
macrophages"
11:25AM – 11:35PM Speaker 5, from abstracts * This presenter has indicated a relationship which, in the context of their presentation, could be perceived by some as a real or apparent
conflict of interest but do not consider that it will influence their presentation. The disclosures have been reviewed and conflicts of interest
have been resolved by the Conference Organizer in accordance with the ACCME Standards for Commercial Support.
11:40PM – 11:50PM Speaker 6, from abstracts
12:00 – 1:00 Lunch
1:15PM – 2:15PM Meet the Expert Session: “You and OPN: Match.com”
Moderator: Lalita R. Shevde-Samant, Ph.D. University
of South Alabama Cancer Research Institute Mobile,
AL.
Free Afternoon
4:00PM – 6:00PM Poster Session 2
6:00PM – 7:00PM Dinner
Session 4: 7:00PM – 10:00PM Osteopontin and Related Proteins: Inflammation
and pathological angiogenesis
Chair: W. Robert Taylor,
Emory University School of Medicine,
Medicine/Cardiology, 1639 Pierce Dr, Atlanta, GA
7:00PM - 7:25PM Speaker 1, Maria F. Gomez Ph. D. Dept. of Clinical
Sciences Lund University, Malmö, Sweden
Title: "NFAT and osteopontin in vascular
complications of diabetes"
7:30PM – 7:55PM Speaker 2, Alicia Lyle, Emory University School of
Medicine, Atlanta GA
Title: "The Role of Osteopontin in Post-Ischemic Neovascularization"
8:00PM – 8:15 PM Break
8:20PM – 8:45PM Speaker 3, Krishna Singh, East Tennessee State
University, Johnson City, TN
Title: “Osteopontin: role in cardiac myocyte apoptosis
and myocardial remodeling”
8:50PM – 9:15PM Speaker 4, Johan M. Lorenzen, Hanover Medical
School, Hannover, Germany
Title: "Regulation of acute and chronic kidney disease:
role of osteopontin"
9:20PM – 9:30PM Speaker 5, from abstracts
9:35PM – 9:45PM Speaker 6, from abstracts * This presenter has indicated a relationship which, in the context of their presentation, could be perceived by some as a real or apparent
conflict of interest but do not consider that it will influence their presentation. The disclosures have been reviewed and conflicts of interest
have been resolved by the Conference Organizer in accordance with the ACCME Standards for Commercial Support.
Wednesday, August 8, 2012
7:30AM – 9:00AM Breakfast
Session 5: 9:00AM – 12:15PM Osteopontin and Related Proteins: Cadiovascular
pathology
Chair: Keith Hruska Washington University at St.
Louis, Department of Pediatrics 5th Fl MPRB Campus
Box 8208 660 S. Euclid Avenue St. Louis, MO
9:00AM - 9:25AM Speaker 1, Keith Hruska, Washington University at St.
Louis, Department of Pediatrics, St. Louis, MO
Title: TBD
9:30AM –9:55AM Speaker 2, Dwight Towler, Department of Medicine,
Washington University at St Louis, St. Louis, MO
Title: "Osteopontin Signaling in Diabetic
Arteriosclerosis"
10:00AM – 10:25AM Speaker 3, Cecilia Giachelli, Department of
Bioengineering, University of Washington, Seattle WA
Title: "Role of Osteopontin in Vascular Calcification"
10:30AM – 10:50AM FASEB Sponsored Coffee Break
10:55AM – 11:20AM Speaker 4, Meena Chellaiah, Department of
Oncology and Diagnostic Sciences, Dental School,
University of Maryland, Baltimore, MD
Title: “Osteopontin: Associations with VEGF/VEGR1
expression and invasion of prostate cancer cells”
11:25AM – 11:35PM Speaker 5, from abstracts
11:45PM – 11:55PM Speaker 6, from abstracts
12:00PM – 1:00 Lunch
Free Afternoon
4:00PM – 6:00PM Poster Session 3
6:00PM – 7:00PM Dinner
Session 6: 7:00PM – 9:45PM Osteopontin and Related Proteins: Bone
mineralization and pathological calcification
Chair: Adele L. Boskey,
Hospital for Special Surgery, Musculoskeletal Integrity
Program, 535 E 70th St, New York, NY * This presenter has indicated a relationship which, in the context of their presentation, could be perceived by some as a real or apparent
conflict of interest but do not consider that it will influence their presentation. The disclosures have been reviewed and conflicts of interest
have been resolved by the Conference Organizer in accordance with the ACCME Standards for Commercial Support.
7:00PM - 7:25PM Speaker 1, Harvey Goldberg School of Dentistry and
CIHR Group in Skeletal Development and
Remodeling, University of Western Ontario, London,
Ont., Canada
Title: “Modulation of Mineral Formation by
Osteopontin and Related Proteins”
7:30PM – 7:55PM Speaker 2, Chunlin Qin Department of Endodontics,
the University of Texas-Houston Health Science
Center Dental Branch, MD Anderson Blvd, Suit 307,
Houston, TX
Title: “Dentin Matrix Protein 1 (DMP1) in
Biomineralization and Phosphate Homeostasis’
8:00PM – 8:15 PM Break
8:20PM – 8:45PM Speaker 3, Brian Foster, NIAMS/NIH Lab for Oral
Connective Tissue Biology
Title: “Roles of SIBLING proteins in periodontal
development and regeneration”
8:50PM – 9:15PM Speaker 4, Lauren Pachman Department of
Pediatrics, Division of Rheumatology, Northwestern
University, Feinberg School of Medicine, Cure JM
Center of Excellence in Juvenile Myositis Research,
The Children's Memorial Research Center, Chicago,
IL
Title: “Dystrophic Calcifications in Juvenile
Dermatomyositis: Osteopontin and other Siblings”
9:20PM – 9:30PM Speaker 5, from abstracts
9:35PM – 9:45PM Speaker 6, from abstracts
Thursday, August 9, 2012
7:30AM – 9:00AM Breakfast
Session 7: 9:00AM – 12:15PM Osteopontin and Related Proteins: Innate and
adaptive immunity
Chair: Mari Shinohara, Duke University, Immunology,
Duke Medical Center, 338 Jones Building, DUMC-
3010, Durham,
NC
9:00AM - 9:25AM Speaker 1, Harvey Cantor Harvard Medial School,
Dana-Farber Cancer Institute, Boston, MA
Title: TBD * This presenter has indicated a relationship which, in the context of their presentation, could be perceived by some as a real or apparent
conflict of interest but do not consider that it will influence their presentation. The disclosures have been reviewed and conflicts of interest
have been resolved by the Conference Organizer in accordance with the ACCME Standards for Commercial Support.
9:30AM –9:55AM Speaker 2, Vily Panoutsakopoulou, Biomedical
Research Foundation Academy of Athens, Greece
Title: “Immune tolerance and osteopontin”
10:00AM – 10:25AM Speaker 3, Toshimitsu Uede Hokkaido University,
Institute for Genetic Medicine, Sapporo, Japan
Title: “Tissue matricellular proteins regulates effector
T cell egress from draining lymph nodes via alpha9
integrin-signaling”
10:30AM – 10:50AM Break
10:55AM – 11:20AM Speaker 4, Nagahiro Minato, Kyoto University, Kyoto.
Japan
Title: “T cell immunosenescence and osteopontin;
Involvement in autoimmune diseases and
malignancy”
11:25AM – 11:35PM Speaker 5, from abstracts
11:45PM – 11:55PM Speaker 6, from abstracts
12:00PM – 1:00 Lunch
12:00PM – 12:30PM Business Meeting
12:30PM – 1:30PM Lunch
Free Afternoon
1:00PM Optional Organized Group Activity
4:00PM – 6:00PM Poster Session 4 (Last name N-Z presenting)
6:00PM – 7:30PM Dinner
Session 8: 7:00PM – 9:45PM Osteopontin and Related Proteins: Auto-immune
diseases and allergies
Chair: Toshimitsu Uede, Hokkaido University, Institute
for Genetic Medicine, Kita-15, Nishi-7, Kit-ku Sapporo
06-06815,
Japan
7:00PM - 7:25PM Speaker 1, Silvia Bulfone-Paus, Department of
Immunology and Cell Biology, Research Center
Borstel, Borstel, Germany
Title: “Immunmodulatory activities of mast cellsecreted osteopontin”
7:30PM – 7:55PM Speaker 2, Lawrence Leung, Stanford University * This presenter has indicated a relationship which, in the context of their presentation, could be perceived by some as a real or apparent
conflict of interest but do not consider that it will influence their presentation. The disclosures have been reviewed and conflicts of interest
have been resolved by the Conference Organizer in accordance with the ACCME Standards for Commercial Support.
School of Medicine, Stanford University
Title: "Thrombin and Carboxypeptidase B Cleavage of
Osteopontin"
8:00PM – 8:15 PM Break
8:20PM – 8:45PM Speaker 3, Mari Shinohara, Department of
Immunology, Duke University
Title: “Osteopontin in innate immunity”
8:50PM – 9:15PM Speaker 4, Charles E. Egwuagu, Molecular
Immunology Section, Laboratory of Immunology,
National Eye Institute, NIH Bethesda
Title: “Trafficking of Autoreactive Memory T cells into
Bone Marrow of Mice with Chronic Uveitis is
dependent on STAT3,41 and Osteopontin”
9:20PM – 9:30PM Speaker 5, from abstracts
9:35PM – 9:45PM Speaker 6, from abstracts

5 Sep - 10 Sep 2012
Saxtons river
United States of America
meeting website