Biology and Pathobiology of Krüppel-like Factors (KLFs)

Biology and Pathobiology of Krüppel-like Factors (KLFs)
+ show speakers and program
Co-Organizers:
Joyce A. Lloyd
Virginia Commonwealth University
Richmond, Virginia
Mukesh Jain
Case Western Reserve University
Cleveland, Ohio
Ichiro Manabe
University of Tokyo
Tokyo, Japan
Sunday,
August 5, 2012
4:00PM – 9:00AM Conference Registration

6:00PM – 7:00 PM FASEB Opening Reception

7:00PM – 8:30 PM Dinner

8:45PM – 10:00PM James Bieker, Mt. Sinai School of Medicine, New York
Erythroid Krüppel-like Factor and control of erythropoiesis
Monday,
August 6, 2012
7:30AM – 9:00AM Breakfast

Session 1:
9:00AM – 12:15PM
Krüppel-Like Factors in Muscle Physiology and
Pathophysiology
Anne Hamik, Case Western Reserve University

9:00AM – 9:15AM Welcome from FASEBThis activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.

9:15AM - 9:45AM Jerry Lingrel, University of Cincinnati
KLF2 and vascular pathophysiology

9:45AM –10:15AM Anne Hamik, Case Western Reserve University
Krüppel-like factors and endothelial biology

10:15AM – 10:30 AM Short Talk Selected From Submitted Abstracts

10:30AM – 11:00AM Group photo & FASEB Sponsored Coffee Break

11:00AM – 11:30AM Anthony Gerber, National Jewish Health
Mechanisms and consequences of glucocorticoid and KLF15
crosstalk in the lung

11:30AM – 12:00PM Darwin Jeyaraj, Case Western Reserve University
Circadian control of sudden cardiac death by KLFs

12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts

12:15PM – 1:15PM Lunch
Free Afternoon or Career Development Session
1:30PM – 3:30PM C. William Balke, University of California, San Francisco
Research Career Development for Junior Investigators
4:00PM – 6:00PM Poster Session 1
6:00PM – 7:00PM Dinner

Session 2:
7:00PM – 9:45PM
Structure/Function Studies of Krüppel-Like Factors
Takashi Umehara, RIKEN, Yokohama, Japan

7:00PM - 7:30PM Takashi Umehara, RIKEN, Yokohama, Japan
Structural studies of KLFs and KLF-associated factors
7:30PM – 8:00PM Nick Grishin, University of Texas Southwestern
Evolution of KLF zinc fingers and associated domains

8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts

8:15PM – 8:30PM Break

8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts

8:45PM – 9:15PM Goutham Narla, Mt. Sinai School of Medicine, New York
Regulation of KLF6 gene function by alternative splicing

9:15PM – 9:45PM Gwen Lomberk, , Mayo Clinic, Rochester, MN
Functional Impact of KLF-Mediating Coupling to Histone
MethylasesThis activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.
Tuesday,
August 7, 2012
7:30AM – 9:00AM Breakfast

Session 3
9:00AM – 12:15PM
Krüppel-Like Factors in Differentiation
Ichiro Manabe, University of Tokyo

9:00AM - 9:30AM Stefan Schoenfelder, Babraham Institute, Cambridge
Erythroid Krüppel-like Factor and the transcriptional interactome

9:30PM –10:00AM Toru Suzuki, University of Tokyo
KLF6 in cardiovascular and metabolic disease
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts

10:15AM – 10:45AM FASEB Sponsored Coffee Break

10:45AM – 11:15AM Brandon Atkins
Krüppel-Like Factors in cerebrovascular disease

11:15AM – 11:45AM Akiko Hata, University of California, San Francisco
Regulation of KLF4 by miR-145 in the regulation of vascular
smooth muscle cell phenotype

11:45AM – 12:15PM Joyce Lloyd, Virginia Commonwealth University, Richmond
Krüppel-like factors in erythroid and cardiovascular development

12:15PM – 1:15PM
1:15PM – 2:15PM
Lunch
Meet the Expert

Free Afternoon
4:00PM – 6:00PM Poster Session 2
6:00PM – 7:00PM Dinner

Session 4:
7:00PM – 9:45PM
Krüppel-like Factors in Tumor Biology
Vincent Yang, Stony Brook University Medical Center
7:00PM - 7:30PM Vincent Yang, Stony Brook University Medical Center
The role of Krüppel-like factors in intestinal tumorigenesis
7:30PM – 8:00PM Jonathan Katz, University of Pennsylvania
Krüppel-like factors in invasive squamous cell cancer

8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts

8:15PM – 8:30PM Break
This activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts

8:45PM – 9:15PM Jihe Zhao, University of Central Florida
Role of KLF8 in DNA repair: new insights from the KLF8-PARP1
interaction

9:15PM – 9:45PM Agnieszka Bialkowska, Stony Brook University Medical Center
Identification of small-molecule inhibitors of colorectal cancer
oncogene KLF5 expression by ultrahigh-throughput screening
Wednesday,
August 8, 2012
7:30AM – 9:00AM Breakfast

Session 5
9:00AM – 12:15PM
Krüppel-Like Factors in Metabolic Control and Disorders
Ryozo Nagai, University of Tokyo

9:00AM - 9:30AM Koh Ono, Kyoto University
miRNA and KLFs in metabolic control

9:30PM –10:00AM Katsuhito Fujiu, University of Tokyo
Krüppel-like factors and kidney function
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts

10:15AM – 10:45AM FASEB Sponsored Coffee Break

10:45AM – 11:15 AM Saptarsi Haldar, Case Western Reserve University
Krüppel-like factors in skeletal muscle metabolism

11:15 AM – 11:45 AM Merlin Crossley, University of New South Wales, Sydney, Australia
Roles of KLF3 and KLF8 in adipogenesis

11:45AM – 12:15PM Navtej Buttar, Mayo Clinic, Rochester, MN
Regulatory role of Kruppel Like factors in cancer cell metabolism

12:15PM – 1:15PM Lunch
Free Afternoon
4:00PM – 6:00PM Poster Session 3
6:00PM – 7:00PM Dinner

Session 6:
7:00PM – 9:45PM
Krüppel-Like Factors in Stem Cell Biology and Embryonic
Development
Mukesh Jain, Case Western Reserve University
7:00PM - 7:30PM Masatsuga Ema, University of Tsukuba, Japan
Krüppel-like factors in ES cellsThis activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.
7:30PM – 8:00PM Andrew Perkins, University of Queensland, Brisbane, Australia
KLF3 and embryonic stem cell differentiation

8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts

8:15PM – 8:30PM Break

8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts

8:45PM – 9:15PM Mona Nemer, University of Ottawa, Ontario, Canada
KLF13 in heart development and homeostasis

9:15PM – 9:45PM Tadashi Yoshida, Keio University, Tokyo
Role of Klf4 in cardiovascular development and disease
Thursday,
August 9, 2012
7:30AM – 9:00AM Breakfast

Session 7
9:00AM – 12:15PM
Krüppel-Like Factors in Inflammatory and Immune Responses
Stephen Jameson, University of Minnesota

9:00AM - 9:30AM Stephen Jameson, University of Minnesota
KLF2 in the trafficking and differentiation of T and B cells

9:30PM –10:00AM Mark Feinberg, Harvard University
Role of KLF10 in TGF- signaling: at the crossroads of
inflammation, angiogenesis, and vascular repair
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts

10:15AM – 10:45AM FASEB Sponsored Coffee Break

10:45AM – 11:15AM Ganapathi Mahabaleshwar, Case Western Reserve University
KLFs as essential regulators of myeloid biology

11:15AM – 12:00PM Yuan Lu, Case Western Reserve University
KLF15 and vascular disease

12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts

12:15PM – 12:45PM Business Meeting

12:45PM – 1:45PM Lunch
Free Afternoon
1:00PM – 6:00PM Optional Organized Group Activity
6:00PM – 7:00PM DinnerThis activity is not being planned in accordance with the ACCME Standards for Commercial Support. AMA PRA
Category 1 Credit(s)™ will not be offered.

Session 8:
7:00PM – 9:45PM
Krüppel-Like Factors and Cell Signaling
Raul Urrutia, Mayo Clinic, Rochester, MN
7:00PM - 7:30PM Raul Urrutia, Mayo Clinic, Rochester, MN
KLFs, chromatin dynamics and TGFbeta signaling
7:30PM – 8:00PM John Hawse, Mayo Clinic, Rochester, MN
Role of KLF10 in mediating Wnt signaling in bone

8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts

8:15PM – 8:30PM Break

8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts

8:45PM – 9:15PM Rosalia Simmen, University of Arkansas for Medical Sciences
Krüppel-like factors and uterine pathologies

9:15PM – 9:45PM Guillermo García-Cardeña, Harvard University
Krüppel-like factors as novel therapeutic targets for endothelial
dysfunction

Friday,
August 10, 2012
7:30AM – 8:30AM Breakfast

Session 9
8:30AM – 11:30PM
KLF Resources
Jonathan Katz, University of Pennsylvania

8:30AM - 9:30AM Jonathan Katz, University of Pennsylvania
Developing Shared Resources for KLF Research: making a toolbox
9:30AM – 9:45AM Short Talk Selected From Submitted Abstracts

9:45AM – 10:00AM Break

10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts

10:15AM – 10:45AM Srinivasan Chandrasegaran, Johns Hopkins University
Genome Engineering of Eukaryotic Cells

10:45AM – 11:15AM Mukesh Jain, Case Western Reserve University
The State of the KLFs
11:15AM-11:30AM Closing Comments
11:30AM Departures
Boxed Lunches Available

5 Sep - 10 Sep 2012
snowmass village
United States of America
meeting website