Nutrient Sensing and Metabolic Signaling


+ show speakers and program
Sunday, August 10, 2014
4:00PM – 9:00PM Conference Registration

6:00PM – 7:00 PM FASEB Opening Reception

7:00PM – 8:30 PM Dinner

8:45PM – 9:00PM Welcome and Opening Remarks

9:00 – 10:00PM Keynote Address:
Gerald I Shulman MD, PhD, Yale University
“Cellular Mechanisms of Lipid-Induced Insulin Resistance:
Implications for Obesity, Lipodystrophy and Type 2 Diabetes”

Monday, August 11, 2014
7:30AM – 9:00AM Breakfast

Session 1:
9:00AM – 12:15PM
Regulation of Chromatin Structure and Transcription by
Nutrients
Michael Kilberg, PhD, University of Florida

9:00AM – 9:15AM Welcome from FASEB

9:15AM - 9:50 AM Michael Kilberg, PhD, University of Florida
“Transcription Factor Networks Associated with Amino AcidLimitation”

9:50AM –10:25AM Joan Conaway, PhD, Stowers Institute for Medical Research
“ATF6 Recruits Multiple Chromatin-Associated Complexes”

10:25AM–10:40AM Short Talk Selected From Submitted Abstracts

10:40AM – 11:05AM Group photo & FASEB Sponsored Coffee Break

11:05AM – 11:40AM Steven Zeisel, MD, PhD, University of North Carolina at Chapel Hill
“Choline, Metabolic Signaling and Gene Expression/Epigenetics”

11:40AM – 12:15PM Graham Burdge, PhD, University of Southampton
“Nutriepigenomics: Why You Are What You Eat”

12:15PM – 1:15PM Lunch

Free Afternoon

4:00PM – 6:00PM Poster Session 1

6:00PM – 7:00PM Dinner

Session 2:
7:00PM – 9:55PM
Insulin, mTOR and AMPK in Metabolic Control
Brendan Manning, PhD, Harvard University

7:00PM - 7:05PM Welcome and Introduction

7:05PM - 7:40PM Brendan Manning, PhD, Harvard University
“Metabolic Control of Cell Growth by mTOR”

7:40PM – 8:15PM David Sabatini, MD, PhD, Whitehead Institute
“Amino Acid Sensing by mTOR”

8:15PM – 8:30PM Short Talk Selected From Submitted Abstracts

8:30PM – 8:45PM Break

8:45PM – 9:20PM Reuben Shaw, PhD, Salk Institute for Biological Studies
“AMPK Signaling Controls Acute and Prolonged Metabolic
Reprogramming”

9:20PM – 9:55PM Nada Kalaany, PhD, Harvard Medical School
“Differential Sensitivity of Tumors to Dietary Restriction”

Tuesday, August 12, 2014
7:30AM – 9:00AM Breakfast
Session 3
9:00AM – 11:55AM
Nutrient Stress Signals and the Unfolded Protein Response
Ronald Wek, PhD, Indiana University School of Medicine

9:00AM - 9:05AM Welcome and Introduction

9:05AM - 9:40AM Ronald Wek, PhD, Indiana University School of Medicine“Nutrient Stress Signals and Translational Control”

9:40AM –10:15AM Tracy Anthony, PhD, Rutgers University
“Targeting eIF2 Kinase Signaling to Improve Treatment of Disease”

10:15PM – 10:30AM Short Talk Selected From Submitted Abstracts

10:30AM – 10:45AM FASEB Sponsored Coffee Break

10:45AM – 11:20AM Fumihiko Urano, MD, PhD, Washington University in St. Louis
“Endoplasmic Reticulum: an Interface between the Immune System
and Metabolism”

11:20AM – 11:55AM Ira Tabas, MD, PhD, Columbia University
“Calcium Signaling and ER Stress in Obesity and Type 2 Diabetes”

12:00PM – 1:00PM Lunch

1:00PM – 2:00PM Meet the Expert

Free Afternoon

6:00PM – 7:00PM Dinner

Session 4:
7:00PM – 9:55PM
Liver Lipid Metabolism
Timothy Osborne, PhD, Sanford Burnham Medical Research
Institute

7:00PM - 7:05PM Welcome and Introduction

7:05PM - 7:40PM Timothy Osborne, PhD, Sanford Burnham Medical Research
Institute
“New Roles and Regulation for SREBPs in Growth and Metabolism”

7:40PM – 8:15PM Morris Birnbaum, MD, PhD, University of Pennsylvania
“The Regulation of Hepatic Lipid Metabolism by Insulin”

8:15PM – 8:30PM Short Talk Selected From Submitted Abstracts

8:30PM – 8:45PM Break

8:45PM – 9:20PM James Ntambi, PhD, University of Wisconsin-Madison
“Role of Stearoyl-CoA Desaturase-1 in Lipid Storage and
Metabolism”

9:20PM – 9:55PM Jay Horton, MD, University of Texas Southwestern Medical Center
“Characterization of New Post-Transcriptional Regulators of Fatty
Acid Synthesis”

Wednesday, August 13, 2014
7:30AM – 9:00AM Breakfast

Session 5 Nutrient Sensing and Metabolic Signaling in Adipose Tissue
9:00AM – 11:55AM Naima Moustaid-Moussa, PhD, Texas Tech University

9:00AM - 9:05AM Welcome and Introduction

9:05AM - 9:40AM Nishan Kalupahana, PhD, University of Peradeniya School of
Medicine, Sri Lanka
“At the Cross Roads of Obesity and Immunology”

9:40AM –10:15AM Kate Claycombe, PhD, USDA Agricultural Research Service
“Epigenetics and Nutrient Sensing in Adipose Tissue”

10:15AM – 10:30AM Short Talk Selected From Submitted Abstracts

10:30AM – 10:45AM FASEB Sponsored Coffee Break

10:45AM – 11:20AM Naima Moustaid-Moussa, PhD, Texas Tech University
“Omega 3 Fatty Acids Regulation of White and Brown Fat
Metabolism”

11:20AM – 11:55AM Alyssa Hasty, PhD, Vanderbilt University School of Medicine
“A Role for the Micronutrient, Iron, in Adipose Tissue Homeostasis”

12:00PM – 1:00PM Lunch

Free Afternoon

4:00PM – 6:00PM Poster Session 2

6:00PM – 7:00PM Dinner

Session 6:
7:00PM – 9:55PM
Nutrient Sensing and Metabolic Signaling in Skeletal Muscle
Blake Rasmussen, PhD, University of Texas Medical Branch
Galveston

7:00PM - 7:05PM Welcome and Introduction

7:05PM - 7:40PM Blake Rasmussen, PhD, University of Texas Medical Branch
Galveston
“Protein/Amino Acid Sensing and Metabolic Signaling in Human
Skeletal Muscle”

7:40PM – 8:15PM Scot Kimball, PhD, Pennsylvania State University College of
Medicine
“Macronutrient Regulation of Alternative Pre-mRNA Splicing in
Muscle”

8:15PM – 8:30PM Short Talk Selected From Submitted Abstracts

8:30PM – 8:45PM Break

8:45PM – 9:20PM Debbie Muoio, PhD, Duke University
“Lipid-Induced Mitochondrial Stress and Glucose Transport in
Skeletal Muscle”

9:20PM – 9:55PM Christopher Adams, MD, PhD, University of I9:20PM – 9:55PM Christopher Adams, MD, PhD, University of Iowa
“Role of ATF4 in Skeletal Muscle Atrophy”

Thursday, August 14, 2014
7:30AM – 9:00AM Breakfast

Session 7
9:00AM – 12:10PM
Nutrient Sensing and Metabolic Signaling in the Central
Nervous System and Beyond
Susan Hutson, PhD, Virginia Tech University

9:00AM - 9:05AM Welcome and Introduction

9:05AM - 9:40AM Susan Hutson, PhD, Virginia Tech University
“Branched Chain Amino Acid and α-Keto Acids Regulate mTOR
Signaling in Brain”

9:40AM –10:15AM Christopher Morrison, PhD, Pennington Biomedical Research
Center
“Molecular Detectors Linking Dietary Protein to Behavior and
Metabolism

10:15AM – 10:30AM Short Talk Selected From Submitted Abstracts

10:30AM – 10:45AM FASEB Sponsored Coffee Break

10:45AM – 11:20AM Stephen Simpson, PhD, University of Sydney, Australia “The
Geometry of Macronutrient Balance and Protein Leverage”

11:20AM – 11:55AM Gary Schwartz, PhD, Albert Einstein College of Medicine
“Distributed Nutrient Sensing in the Integrated Control of Energy
Balance”

11:55AM – 12:10PM Business Meeting

12:10PM – 1:10PM Lunch

Free Afternoon

1:00PM – 6:00PM Optional Organized Group Activity

6:00PM – 7:00PM Dinner

Session 8:
7:00PM – 9:55PM
Nutrient Sensing and Metabolic Signaling in the
Gastrointestinal Tract
Judy Storch, PhD, Rutgers University

7:00PM - 7:05PM Welcome and Introduction

7:05PM - 7:40PM Judy Storch, PhD, Rutgers University
“Differential Regulation of Whole Body Energy Homeostasis by
Enterocyte Fatty Acid-Binding Proteins

7:40PM – 8:15PM Nada Abumrad, PhD, Washington University in St. Louis
“Dietary Lipid Signals the Arrival of a Meal via CD36-Mediated
Signaling

8:15PM – 8:30PM Short Talk Selected From Submitted Abstracts

8:30PM – 8:45PM Break

8:45PM – 9:20PM Liping Zhao, PhD, Shanghai Jiao Tong University
“Nutritional Modulation of Gut Microbiota for Metabolic Health

9:20PM – 9:55PM Sarah Campbell, PhD, Rutgers University
“Impact of Exercise on Gut Microbiota”

Friday, August 15, 2014
7:30AM – 8:30AM Breakfast

8:30AM-11:30AM Departures
Boxed Lunches Available

10 Aug - 15 Aug 2014
Big Sky
United States of America
meeting website