Frontiers in Metabolism: From Molecular Physiology to Systems Medicine

Conversion and processing of small molecules by cellular metabolic networks provides the cell with the necessary nutrients, biomass precursors and energy resources. Metabolism has therefore traditionally been seen as a downstream effector layer in the regulatory architecture of the cell. Recent work, however, revealed that metabolism commands cellular and organismal physiology and is closely intertwined with multiple signalling pathways.

Studies on the mechanisms of metabolic sensing, characterisation of the system-level impact of metabolism on regulatory networks and discovery of new metabolic coordination mechanisms have provided unforeseen insights into the crosstalk between metabolism and cellular homeostasis, which show a remarkable evolutionary conservation.

This very active field of investigation is interdisciplinary in nature and requires a variety of approaches, from investigations at the molecular and cellular levels to system-wide genetic and integrative approaches in multiple species. This symposium will therefore bring together leading researchers from a variety of disciplines and disease areas to stimulate cross-fertilising discussions and exchanges.

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Speakers and Chairs

Keynote Speaker



Hall
Michael Hall
University of Basel, Switzerland

Ruvkun
Gary Ruvkun
Harvard Medical School, USA



Confirmed Speakers

Auwerx
Johan Auwerx
EPFL, Switzerland

Anne_Brunet
Anne Brunet
Stanford University School of Medicine, USA

Dillin
Andy Dillin
University of California, Berkeley, USA

Evans
Ronald Evans
Salk Institute for Biological Studies, USA

Hentze
Matthias Hentze
EMBL Heidelberg, Germany

Larsson
Nils-Göran Larsson
MPI for Biology of Ageing, Germany

Leinwand
Leslie Leinwand
University of Colorado Boulder, USA

Lippincott-Schwartz
Jennifer Lippincott-Schwartz
National Institutes of Health, USA

Lusis
Aldons J. Lusis
UCLA, Los Angeles, USA

lutolf
Matthias Lutolf
EPFL, Switzerland

Mangelsdorf
David Mangelsdorf
UT Southwestern Medical Center, USA

Mootha
Vamsi Mootha
Harvard Medical School, USA

Olson
Eric Olson
UT Southwestern Medical Center, USA

Partridge
Linda Partridge
Institute of Healthy Ageing, UK

Pelicci
Pier Giuseppe Pelicci
IFOM-IEO, Italy

David_Ron
David Ron
University of Cambridge, UK

Sauer
Uwe Sauer
ETH Zurich, Switzerland

Schoonjans
Kristina Schoonjans
EPFL, Switzerland

Shaw
Reuben Shaw
Salk Institute for Biological Studies, USA

Suomalainen
Anu Suomalainen
University of Helsinki, Finland

Thomas_Langer
Thomas Langer
University of Cologne, Germany

Walhout
Albertha J Walhout
University of Massachusetts, USA

Zechner
Rudolf Zechner
University of Graz, Austria

17 Nov - 20 Nov 2014
heidelberg
Germany
meeting website