Wnt signalling: Stem cells, development and disease

Wnt ligands are key regulators of development, stem cell biology and regeneration. The dynamic control of Wnt signaling regulates basic cellular processes including cell proliferation, differentiation, migration and apoptosis. Recent advances in our understanding of signaling mechanisms have provided the tools and conceptual framework for the analysis of Wnt deregulation in disease, leading to the emergence of early-stage therapies for the treatment of disease. Further details about Wnt Meetings may be found on the Wnt homepage.

TOPICS
• Basic mechanisms of signal transduction and their role in development
• Wnt interactions with other signaling pathways
• Human oncogenesis and other diseases
• Therapeutic targeting and drug development

+ show speakers and program

Midday-1800 Registration/Arrival
Book Wednesday afternoon tours Tour desk @ Reception

1700 - 1845 Welcome drinks and finger foood
1845 - 1850 Welcome and Introduction - Elizabeth Vincan
1850 - 1900 Chair and introduction: Nick Barker
1900 - 2000 Session #1: Wnt, Stem Cells and Disease
Keynote address: Hans Clevers (Netherlands)
Intestinal Stem Cells
2000 - 2230 Poster session #1 with Trade displayInformal discussion
Cheese, nibbles and wine
0630 – 0800 Breakfast
0820 - 0830 Chair and introduction: Elizabeth Vincan
0830 - 1000 Session #2: Wnt signalling – Stem Cells
0830 – 0930 Plenary #1: Roel Nusse (USA)
Stem cells and Wnt Signalling
0930 – 1000 Jane Visvader: Stem cells, mammary gland, breast cance

1000 - 1030 Coffee, Posters, Trade display

1030 – 1200 Session #3: Development/Stem cells
1030 - 1100 Hiroshi Sawa: Asymmetric cell division
1100 - 1115 Talk selected from Abstracts
1115 - 1130 Talk selected from Abstracts
1130 - 1200 Terry Yamaguchi: Wnts in development

1200 – 1400 Buffet Lunch
1400 - 1530 Session #4: Basic mechanisms: Development I
1400 - 1430 Christof Niehrs: Wnt in embryonic development
1430 - 1445 Talk selected from Abstracts
1445 - 1500 Talk selected from Abstracts
1500 - 1530 Patrick Tam: Wnt in embryonic development

1530 - 1600 Afternoon Tea, Trade Display, Posters
1600 – 1730 Session #5: Basic mechanisms: Development II
1600 - 1630 Stefan Hoppler: Wnt in embryonic development
1630 -1645 Talk selected from Abstracts
1645 - 1700 Talk selected from Abstracts
1700 - 1730 John McAvoy: Wnt in lens development

1800 – 2000 Bar-B-Q
2000 – 2230 Poster session #2 with Trade display.
informal discussions. Cheese, nibbles and wine

0630 – 0800 Breakfast
0830 - 1000 Session #6: Wnt signalling at the membrane/cytoplasm
0830 - 0900 Akira Kikuchi: Wnts apical basal polarity
0900 - 0915 Talk selected from Abstracts
0915 - 0930 Talk selected from Abstracts
0930 - 1000 Mariann Bienz: Dsh

1000 - 1030 Coffee, Posters, Trade display
1030 – 1130 Session #7: Wnt signalling at the membrane/cytoplasm
1030 – 1100 Xi He: Destruction complex
Talk selected from Abstracts

1115 - 1130 Chair and introduction: Rob Ramsay
1130 - 1230 Session #8: Wnt signalling and Cancer
1130 - 1230 Plenary #2: Tony Burgess: APC in colon cancer


1230 – Lunch Boxes

Free afternoon and evening for informal discussions. Suggestions here
0630 – 0800 Breakfast

0830 - 1000 Session #9: Cytoplasm/nucleus
0830 - 0900 Marian Waterman: TCF/LEF
0900 - 0930 Beric Henderson: β-catenin
0930 - 1000 Trevor Dale: Axin/therapeutic targeting

1000 - 1030 Coffee
1030 – 1230 Session #10: Therapeutic targeting / cross talk
1030 - 1100 Feng Cong: Rsponin
1100 - 1130 Dan Wu: Pathway cross talk/small molecule inhibitors
1130 - 1200 Frederic de Sauvage: Stem cells / Hedgehog

1200 – 1400 Buffet Lunch
Lunch with an expert - ECR's and Students chat with the Internatinal Speakers
1400 - 1430 Session #11: Wnt pathway in cancer
1430 - 1445 Talk selected from Abstracts
1445 - 1500 Talk selected from Abstracts
1500 - 1530 Owen Sansom: Intestinal regeneration

1530 - 1600 Afternoon Tea
1600 – 1700 Session #12: Wnt pathway in cancer
1600 - 1630 Steve Stacker: Ryk/angiogenesis

1700 - 1715 Introduction and chair – Stefan Hoppler. Poster Prizes
1715 - 1815 Session #13: Wnt, stem cells, regenerative medicine
1715 – 1815 Plenary #3: Randall Moon
Stem cells and regeneration
1815 - 1820 Conference close - Elizabeth Vincan

1930 - 2230 Conference Dinner and Star-gazing Amphitheatre, Cable Beach Club

6 Oct - 10 Oct 2014

broom
Australia
meeting website