Enzyme mechanisms by biological systems

Research in biological catalysis is undergoing major changes and the field is expanding owing to integration of efforts across different disciplines and application of state-of-the-art methods. This EMBO Conference will bring together leading European and US enzymologists working on biological catalysis, mechanisms and systems.
In-depth understanding of catalysis is challenging and this underpins exploitation of enzymes in processing, chemicals manufacturing and drug discovery. With the increased importance of industrial biotechnology, there has never been a better time to move towards design/redesign of enzyme catalysts in a predictable way using a structural-mechanistic knowledge base.
This EMBO Conference will be an interdisciplinary meeting embracing structural, computational and chemical disciplines, that will appeal to researchers (established and younger workers). It is a continuation of the EMBO Conference series on the theme of Enzyme Mechanisms, previously held in Hamburg (2010) and Groningen (2012), and the biannual Trends in Enzymology conferences.
We aim at this meeting to capture the global field-leading developments that will contribute to the underpinning science base and enable more effective exploitation of enzyme catalysts in industrial processes.
+ show speakers and program
UNDAY 1 JUNE
14:00 – 18:00 Arrival │ Registration
18:00 - 19:00
Plenary Lecture Stephen Benkovic (Pennsylvania, US)
19:00 Welcome Reception │Poster Session I
MONDAY 2 JUNE

Session I : New Frontiers in Enzymology
09:00 - 09:30
Don Hilvert (Hönggerberg, CH)
09:30 – 10:00
Peter Graber (Freiburg, DE)
10:00 – 10:30
Martin Warren (Kent, UK)
10:30 – 11:00
Tea and Coffee
11:00 – 11:30
Judith Klinman (Berkeley, US)
11:30 – 12:00
Adrian Mulholland (Bristol, UK)
12:00 - 12:30
Ruedi Allemann (Cardiff, UK)
12:30 – 13:45
Lunch
13:45 – 14:00
Mini-talk from poster winner
Session II : Enzyme Mechanism & Isotope Effects
14:00 – 14:30
Vern Schramm (New York, US)
14:30 – 15:00
Rob Phillips (Georgia, US)
15:00 – 15:30
Tea and Coffee
15:30 – 16:00
Amnon Kohen (Iowa, US)
16:00 – 16:30
Jiali Gao (Minnesota, US)
16:30 – 17:00
Neil Marsh (Michigan, US)
17:30 – 19:00
Poster Session II & Wine Reception

TUESDAY 3 JUNE 2014

Session III : Enzyme Cofactors
09:00 - 09:30
Thomas Poulos (Irvine, US)
09:30 – 10:00
Bruce Palfey (Michigan, US)
10:00 – 10:30
David Berkowitz (Nebraska, US)
10:30 – 11:00
Tea and Coffee
11:00 – 11:30
Victor Davidson (Florida, US)
11:30 – 12:00
Kai Tittmann (Gottingen, DE)
12:00 - 12:30
Susan Miller (San Francisco, US)
12:30 – 13:45
Lunch
13:45 – 14:00
Mini-talk from poster winner


Session IV : Enzyme Design and Redesign
14:00 – 14:30
Dan Tawfik (Rehovat, IL)
14:30 – 15:00
Marco Fraaije (Groningen, NL)
15:00 – 15:30
Uwe Bornscheuer (Greifswald, DE)
15:30
Tour of Tatton Park, Hall and Gardens
Conference Dinner

WEDNESDAY 4 JUNE 2013
Session V : Medicinal and Structural Enzymology
09:00 - 09:30
Dagmar Ringe (Boston, US)
09:30 – 10:00
David Leys (Manchester, UK)
10:00 – 10:30
Claudia Binda (Pavia, IT)
10:30 – 11:00
Tea and Coffee
11:00 – 11:30
Lucy Waskell (Michigan, US)
11:30 – 12:00
John Kozarich (ActivX Biosciences, US)
12:00 - 12:30
Arwen Pearson (Leeds, UK)
12:30 – 13:45
Lunch
13:45 – 14:00
Mini-talk from poster winner (15 mins)


Session VI : Enzyme Dynamics
14:00 – 14:30
Dorothee Kern (Brandeis, US)
14:30 – 15:00
Martin Weik (Grenoble, FR)
15:00 – 15:30
Jon Waltho (Manchester, UK)
15:30 – 16:00 Closing Remarks | Tea & Coffee | Departure

1 Jun - 4 Jun 2014
manchester
United Kingdom
meeting website