Targeting Cyclic AMP Signalling to Combat Cardiovascular Diseases

Advances in our understanding of the molecular actions of cyclic AMP on cardiac function, vascular remodeling, endothelial barrier function and vascular inflammation have revealed new possibilities for therapeutic targeting to combat cardiovascular disease. This Hot Topic meeting therefore presents an invaluable opportunity for research leaders to network, share expertise and forge new collaborations in this rapidly developing area.

Topics:
Physiological significance
Biochemistry and molecular biology
Pathological contexts
Mitochondrial dynamics and remodeling
Cellular bio-energy
+ show speakers and program
Monday 9 December 2013
08:30 - 09:50 Registration with tea and coffee
Session 1: Cyclic AMP and Cardiovascular Disease - Classical Signalling
Chair: Stephen Yarwood (University of Glasgow)

Monday 9 December 2013
09:50 - 10:00
Welcome and introduction
Tim Palmer (University of Glasgow, United Kingdom)
10:00 - 11:00
Targeting Mitochondria to Restore Impaired Metabolic Adaptation to Exercise
Jane Reusch (University of Colorado, U.S.A)
10:35 - 11:00
Selected oral communication
11:00 - 11:30 Coffee/tea break
Session 2: Cyclic AMP and Vascular Function

Chair: Mark Bond (University of Bristol)
Monday 9 December 2013
11:30 - 12:00
Dynamics of receptor mediated cAMP signalling revealed by FRET microscopy
Moritz B√ľnemann (Philipps-Universit√§t Marburg, Germany)
12:00 - 12:40
Role of the G protein-coupled receptor TGR5 in macrophage activation and atherosclerosis
Thijs Pols (University of Amsterdam, The Netherlands)
12:40 - 12:55
Selected oral communication
12:55 - 13:10
Selected oral communication
13:10 - 13:25
Selected oral communication
13:25 - 14:30 Lunch and informal discussions
Session 3: Novel Cyclic AMP Signalling in the Cardiovascular System (1)

Chair: Tim Palmer (University of Glasgow, United Kingdom)
Monday 9 December 2013
14:30 - 15:00
PDEs as Signalling Gatekeepers in Multiple Vascular Endothelial Cell Compartments
Don Maurice (Queen's University, Canada)
15:05 - 15:20
Selected oral communication
15:20 - 15:35
Selected oral communication
15:35 - 15:50
Selected oral communication
15:50 - 16:20 Coffee and tea break
Session 4: Novel Cyclic AMP Signalling in the Cardiovascular System (2)

Chair: Stephen Yarwood (University of Glasgow, United Kingdom)
Monday 9 December 2013
16:20 - 16:55
Cyclic AMP Signalling during Cardiac Remodelling
Frank Lezoualc'h (University Toulouse Paul Sabatier, France)
16:55 - 17:10
Selected oral communication
17:10 - 17:25
Selected oral communication
17:25 - 19:30 Poster session and drinks reception

9 Dec - 9 Dec 2013
London
United Kingdom
meeting website