Stem Cells and Reprogramming (Z4)

This conference will focus on the mechanisms underlying cellular pluripotency, differentiation, and reprogramming. These will include the understanding of signaling, transcriptional, translational and epigenetic events regulating cell fate transitions. The utility of such cellular regulation for disease modeling and regenerative medicine for multiple organ systems will be examined. Translational efforts in academic and industry that are moving toward regenerative medicine will be highlighted, as will efforts to use stem cell biology for drug discovery and evaluating drug toxicity. The emerging intersection of human genetics and stem cell biology that will lead to more personalized medicine will be a thematic focus woven into most sessions of this conference.
+ show speakers and program
Sunday, April 6
Arrival and Registration Lobby Alcove

Monday, April 7
Keynote Address: Speaker to be Announced

AM Plenary: Regulation of Pluripotency I
John B. Gurdon, University of Cambridge, UK
Nuclear Transfer Reprogramming
Shinya Yamanaka, Center for iPS Cell Research and Application (CiRA), Kyoto University, Japan
Induction of Pluripotency by Defined Factors
Austin G. Smith, University of Cambridge, UK
The Design of Pluripotency
Short Talk(s) Chosen from Abstracts

PM Plenary: Regulation of Pluripotency II
Rudolf Jaenisch, Whitehead Institute for Biomedical Research, USA
Mechanisms of Reprogramming
Robert H. Blelloch, University of California, San Francisco, USA
miRNA Regulation of Pluripotency
Kathrin Plath, University of California, Los Angeles, USA
Epigenetics of Reprogramming
Short Talk Chosen from Abstracts

Poster Session 1

Tuesday, April 8
AM Plenary: Direct Reprogramming (Transdifferentiation)
Deepak Srivastava, Gladstone Institute of Cardiovascular Disease, USA
Direct Reprogramming to the Cardiac
Fate Marius Wernig, Stanford School of Medicine, USA
Direct Reprogramming to the Neural Fate
Speaker to be Announced
Sheng Ding, University of California, San Francisco, USA
Re-Direction of Partially Reprogrammed Cells to Multiple Fates
Short Talk(s) Chosen from Abstracts

PM Plenary: Epigenetics of Reprogramming and Differentiation
Richard A. Young, Whitehead Institute for Biomedical Research, USA
Epigenetic Landscape of Pluripotent Stem Cells
Joanna Wysocka, Stanford University School of Medicine, USA
Enhancer Landscapes in Pluripotency and Differentiation
Benoit G. Bruneau, Gladstone Institute of Cardiovascular Disease, USA
Epigenetic Regulation of Cardiac Differentiation
Short Talk Chosen from Abstracts

PM Poster Session 2

Wednesday, April 9
AM Plenary: Modeling of Disease I
Fred H. Gage, The Salk Institute for Biological Studies, USA
Disease Modeling of Complex Neurologic Disease
Nancy Stagliano, iPierian, Inc., USA
IPSC Models of Alzheimer's Disease: From Platform to Therapeutic Candidate
Clive Svendsen, Cedars-Sinai Regenerative Medicine Institute, USA
iPS Modeling of Spinal Muscular Atrophy
Lior Gepstein, Technion-Israel Institute of Technology, Israel
iPS Modeling of Cardiac Disease
Short Talk(s) Chosen from Abstracts

Workshop: Clinical Progress for Stem Cell Therapies. Sponsored by the California Institute for Regenerative Medicine (CIRM)
*Ingrid W. Caras, California Institute For Regenerative Medicine (CIRM), USA
Eva L. Feldman, University of Michigan, USA
Intraspinal Stem Cell Transplantation in ALS: Results of a Phase I Clinical Trial Robert Lanza, Advanced Cell Technology, USA
ES- and iPS-Derived Cells for Clinical Trials
Philip D. Gregory, Sangamo BioSciences, Inc., USA
Genome Editing with Zinc Finger Nucleases: A Novel Apporach to HIV Therapy
Kevin A. D'Amour, ViaCyte, Inc., USA
ES-Cell Derived Islet Progenitors Delivered in an Immune-Protected Device for Type I Diabetes
Tracy Grikscheit, Children's Hospital Los Angeles, USA
Stem Cell-Derived Replacement Tissue for Children Born with Intestinal Disease
PM Plenary: Models of Human Disease (iPS Focus) (Joint)
Lorenz Studer, Memorial Sloan Kettering Cancer Center, USA
Modeling Defects in Neural Crest Stem Cells
George Q. Daley, Children's Hospital Boston, USA
iPS Models of Hematopoietic Disease
Sangeeta N. Bhatia, Massachusetts Institute of Technology, USA
Modeling Hepocyte Disease
Short Talk Chosen from Abstracts

Poster Session 3

Thursday, April 10
AM Plenary: Translational Applications of Stem Cells
Hideyuki Okano, Keio University School of Medicine, Japan
Repair of Spinal Cord Injury
Yoshiki Sasai, RIKEN Center for Developmental Biology, Japan
Self Assembly of Stem Cells into Organoids
Leonard I. Zon, HHMI/Children's Hospital Boston, USA
Mechanisms of Hematopoietic Differentiation
Masayo Takahashi, RIKEN Center for Developmental Biology, Japan
Retinal Cell Therapy Using iPS Cells
Short Talk(s) Chosen from Abstracts

PM Plenary: Cellular Microenvironments/Synthetic Niches to Control Cell Fate (Joint)
Christopher S. Chen, University of Pennsylvania, USA
Engineered Microenvironments: An Approach to Understand Cell Adhesion, Forces and Assembly into Tissues
Jennifer Lewis, Harvard University, USA
Printing 3D Structures Kristi S. Anseth, HHMI/University of Colorado, USA
Phototunable Hydrogels as Dynamic Cell Niches
Short Talk Chosen from Abstracts

Friday, April 11
Departure

6 Apr - 11 Apr 2014
Squaw Creek
United States of America
meeting website