Frontiers of Structural Biology

The goal of this meeting is to connect leaders in the structural biology field, with particular emphasis on novel methods/technology development, highlights of complex cell biological insights made by pioneering structural efforts (across multiple biophysical disciplines) and contributions made by large-scale, high throughput efforts. Additionally, because of the large amount of structural information that is becoming available (and will continue to do so) we would also like to highlight innovations made in areas of bioinformatics and modeling/design that have begun to harness the increasing structural information. Because this meeting brings together a diverse group of structural biologists that employ a variety of experimental techniques we aim to support the dissemination of cutting edge advances and promote interaction among the vibrant international structural biology community.
+ show speakers and program
Sunday, March 30
Arrival and Registration Ballroom Lobby

Monday, March 31
Keynote Address (Joint): Robert J. Lefkowitz, HHMI/Duke University Medical Center, USA

AM Plenary: Cutting-Edge Biophysics to Study Membrane Protein Conformational Changes (Joint)
Petra Fromme, Arizona State University, USA
Femtosecond Nanocrystallography of Membrane Proteins
Martin J. Lohse, Universit├Ąt W├╝rzburg, Germany
Studying GPCR Conformational Changes Using Fluorescence-Based Assays in Living Cells
Ron O. Dror, D. E. Shaw Research, USA
Revealing Structural Dynamics of GPCR Signaling through Atomic-Level Simulation Wayne L. Hubbell, University of California, Los Angeles, USA
Conformational Dynamics of GPCRs Studied by Site-Directed Spin Labeling

Workshop 1: Advances in Methodologies and Tools for Structural Biology
Short Talks Chosen from Abstracts

PM Plenary: Utilizing Next Generation Technologies for Structural Biology
Wayne A. Hendrickson, Columbia University, USA
Utilization of Advanced Synchrotron Technologies
Aled M. Edwards, University of Toronto, Canada
Structural Genomics of Drug Discovery
Ian A. Wilson, The Scripps Research Institute, USA
Adapting Structural Genomics Machinery to Solve Eukaryotic Complexes
Short Talk Chosen from Abstracts

Poster Session 1

Tuesday, April 1
AM Plenary: Structural and Functional Insights through the Use of Hybrid Methods
Eva Nogales, University of California Berkeley, USA
Hybrid Studies of Transcriptional Machinery
Susan S. Taylor, University of California, San Diego, USA
PKA: Assembly and Localization of Large and Dynamic Macromolecular Signaling Complexes
Andrew B. Ward, The Scripps Research Institute, USA
Structural Studies of Viral Envelope Proteins
Speaker to be Announced
Short Talk(s) Chosen from Abstracts

PM Plenary: Structural Biology of Cellular Processes and Complexes
John Rubinstein, University of Toronto, Canada
Electron Cryomicroscopy of Rotary ATPases
Tatyana Polenova, University of Delaware, USA
MAS NMR Studies of Protein Assemblies
Dinshaw J. Patel, Memorial Sloan-Kettering Cancer Center, USA
Protein-Nucleic Acid Complexes
Short Talk Chosen from Abstracts

Poster Session 2

Wednesday, April 2
AM Plenary: Advances in Membrane Protein Structure Solution
Liz Carpenter, University of Oxford, UK
Structural Biology of Human Membrane Proteins
Katherine A. Henzler-Wildman, Washington University, USA
NMR Studies of EmrE in Bicelles
Eric Gouaux, Oregon Health & Science University, USA
Structure and Function of P2X Receptors
Speaker to be Announced
Short Talk(s) Chosen from Abstracts

Workshop 2: PSI/HT Structural Biology Resources
Short Talks Chosen from Abstracts

PM Plenary: Advances in Imaging Cellular Structure
Carolyn A. Larabell, University of California, San Francisco, USA
Correlative X-Ray Tomography
John Briggs, European Molecular Biology Laboratory, Germany
Correlative Light/Electron Microscopy
Speaker to be Announced
Short Talk Chosen from Abstracts

Poster Session 3

Thursday, April 3
AM Plenary: Extending Structural Knowledge through Informatics and Modeling
Peter D. Kwong, NIAID, National Institutes of Health, USA
Evolution of an Immune Response to HIV
Jens Meiler, Vanderbilt University, USA
Modeling Membrane Proteins from Limited Experimental Data
Andrej Sali, University of California, San Francisco, USA
Modeling Allostery
Speaker to be Announced
Short Talk(s) Chosen from Abstracts

PM Plenary: Applications of Computation and Design
William F. DeGrado, University of California, San Francisco School of Pharmacy, USA
Design of Membrane Proteins
Todd Yeates, University of California, Los Angeles, USA
Engineering Self-Assembling Protein Materials: Design Principles and Applications

Closing Keynote Address (Joint): Brian K. Kobilka, Stanford University School of Medicine, USA
Beta 2 Receptor Conformational Changes

Friday, April 4
Departure

30 Mar - 4 Apr 2014
Snowbird
United States of America
meeting website