HIV Pathogenesis - Virus vs. Host

This meeting will be focused on the latest breakthroughs in basic and translational HIV research with an emphasis on mechanistic models. It will present a detail tour of all the key steps of virus replication from infection to AIDS. The program seamlessly incorporates key aspects of 1) virus entry/exit into the cell, 2) entry into the host, 3) virus-host genetics and co-evolution, 4) virus-host interactions and responses, 5) pathogenesis, 6) reservoirs, latency and reactivation, and 7) HIV and the microbiome at the mucosa. Strong emphasis will be given to these and other areas well represented in the abstracts submitted. Extensive opportunities for interactions will be provided to benefit from exposure to the concurrent meeting.
+ show speakers and program
SUNDAY, MARCH 9

16:00—20:00 Arrival and Registration

MONDAY, MARCH 10

07:00—08:00 Breakfast

08:00—09:00 Keynote Address (Joint)
Registered attendees can view abstracts starting on 02/09/2014

David Baltimore, California Institute of Technology, USA
State of the ART in HIV

09:00—11:15 Portals of Entry and Sites of Dissemination (Joint)
Registered attendees can view abstracts starting on 02/09/2014

J. Victor Garcia-Martinez, University of North Carolina, USA
Mechanistic Analysis of Vaginal HIV Transmission and Prevention

Peter A. Anton, University of California, Los Angeles, USA
Rectal HIV Transmission

Ashley T. Haase, University of Minnesota, USA
Virus-Host Immune Interactions at the Portal of Entry and Vaccine Design to Prevent HIV-1 Transmission to Women

Short Talk(s) Chosen from Abstracts

09:40—10:00 Coffee Break

11:15—13:00 Poster Setup

13:00—22:00 Poster Viewing

On Own for Lunch and Recreation

14:30—16:30 Workshop 1: Role of Animal Models for HIV Research

Short Talks Chosen from Abstracts

16:30—17:00 Coffee Available

17:00—19:00 Host-Viral Co-Evolution
Registered attendees can view abstracts starting on 02/09/2014

Sara L. Sawyer, University of Texas at Austin, USA
Co-Evolutionary "Arms Races" between Retroviruses and their Essential Host Factors

Welkin Johnson, Boston College, USA
TRIM5 Evolution and Cross-Species Transmission

Robert J. Gifford, Aaron Diamond AIDS Research Center, USA
The Evolution and Emergence of Lentiviral Pandemics Since the Neolithic Era

Short Talk Chosen from Abstracts


Following Session is for HIV Vaccines: Adaptive Immunity and Beyond (X3)

17:00—19:00 Programming Durable Immunity
Registered attendees can view abstracts starting on 02/09/2014

Robert A. Seder, NIAID, National Institutes of Health, USA
CD8 T Cell Memory

Mark K. Slifka, Oregon Health & Science University, USA
Potential Mechanisms for Sustaining Long-Term Humoral Immunity

Shane Crotty, La Jolla Institute for Allergy and Immunology, USA
CD4 T Cell Memory

Short Talk Chosen from Abstracts

19:00—20:00 Social Hour w/ Lite Bites

19:30—22:00 Poster Session 1


TUESDAY, MARCH 11

07:00—08:00 Breakfast

08:00—11:00 Viral Entry/Exit and Host Genetics
Registered attendees can view abstracts starting on 02/09/2014

Wesley I. Sundquist, University of Utah School of Medicine, USA
HIV Assembly and Egress

Vineet N. KewalRamani, NCI, National Institutes of Health, USA
HIV Entry and Nuclear Translocation

Fadila Bouamr, National Institutes of Health, USA
The Host and HIV Exit

Janice C. Clements, Johns Hopkins University, USA
Molecular and Cellular Mechanism of Virus Entry and Infection in CNS during HIV and SIV Infection

Short Talk(s) Chosen from Abstracts


Following Session is for HIV Vaccines: Adaptive Immunity and Beyond (X3)

08:00—11:00 Inducing Protective Immunity
Registered attendees can view abstracts starting on 02/09/2014

William H. Robinson, Stanford University School of Medicine, USA
Protective B Cell Responses

Rafi Ahmed, Emory University School of Medicine, USA
Protective T Cell Responses

Jonathan W. Yewdell, NIAID, National Institutes of Health, USA
Influence of Antigen Processing on Immune Responses

Susan W. Barnett, Novartis Vaccines and Diagnostics, Inc., USA
RNA Vaccines

Short Talk(s) Chosen from Abstracts

09:20—09:40 Coffee Break

11:00—13:00 Poster Setup

13:00—22:00 Poster Viewing

On Own for Lunch and Recreation

16:30—17:00 Coffee Available

17:00—19:00 Mechanistic Models of Pathogenesis and Disease
Registered attendees can view abstracts starting on 02/09/2014

Richard D'Aquila, Northwestern University, USA
APOBEC3s and Vif-Positive HIV Pathogenesis

Francisco González-Scarano, University of Texas Health Science Center at San Antonio, USA
Mechanisms of CNS Pathogenesis in HIV Infection

Timothy W. Schacker, University of Minnesota, USA
HIV Pathogenesis: The Lymphatics

Short Talk Chosen from Abstracts


Following Session is for HIV Vaccines: Adaptive Immunity and Beyond (X3)

17:00—19:00 Tackling Global HIV Diversity
Registered attendees can view abstracts starting on 02/09/2014

Beatrice H. Hahn, University of Pennsylvania, USA
Phenotype of Transmitted Founder Viruses

Bette T. Korber, Los Alamos National Laboratory, USA
Incorporating Diversity in Immunogen Design

Speaker to be Announced
Conserved/Universal Vaccines

Short Talk Chosen from Abstracts

19:00—20:00 Social Hour w/ Lite Bites

19:30—22:00 Poster Session 2

WEDNESDAY, MARCH 12

07:00—08:00 Breakfast

08:00—11:00 Host Virus Interactions and Responses
Registered attendees can view abstracts starting on 02/09/2014

Michael Emerman, Fred Hutchinson Cancer Research Center, USA
Evolution of Virus Host Defenses

Theodora Hatziioannou, Aaron Diamond AIDS Research Center, USA
Restriction Factors and the Adaptation of HIV to Non-Human Primates

Andrea Cimarelli, Ecole Normale Superiere de Lyon, France
HIV/SIV Auxiliary Genes

Reuben S. Harris, University of Minnesota, USA
Mutation Driven Evolution and Extinction

Short Talk(s) Chosen from Abstracts


Following Session is for HIV Vaccines: Adaptive Immunity and Beyond (X3)

08:00—11:00 Novel Mechanisms for Vaccine-Induced Protection
Registered attendees can view abstracts starting on 02/09/2014

Silke Paust, Harvard Medical School, USA
NK Cell Memory

Galit Alter, Ragon Institute of MGH, MIT, and Harvard, USA
Integrating Antibody Variable and Constant Region Protective Immune Parameters

Penny L. Moore, National Institute for Communicable Diseases, South Africa
Neutralizing V2 Antibodies

Louis J. Picker, Oregon Health & Science University, USA
T-Cell Based Vaccines

Short Talk(s) Chosen from Abstracts

09:20—09:40 Coffee Break

11:00—13:00 Poster Setup

13:00—22:00 Poster Viewing

On Own for Lunch and Recreation

16:30—17:00 Coffee Available

17:00—19:00 HIV, the Microbiome and the Mucosa
Registered attendees can view abstracts starting on 02/09/2014

Dan R. Littman, HHMI/New York University School of Medicine, USA
Immue Homeostasis and Commensal Bacteria

Nichole R. Klatt, University of Washington, USA
Mucosal Immunity in SIV Infection of Non-Human Primates

Satya Dandekar, University of California, Davis, USA
HIV Pathogenesis: The GALT

Short Talk Chosen from Abstracts


Following Session is for HIV Vaccines: Adaptive Immunity and Beyond (X3)

17:00—19:00 Engineering Protective Immune Responses
Registered attendees can view abstracts starting on 02/09/2014

William Schief, The Scripps Research Institute, USA
Vaccines to Induce Broadly Neutralizing Antibodies

Nicholas Mark Valiante, Novartis Vaccines and Diagnostics, USA
Novel Adjuvants

Speaker to be Announced

Short Talk Chosen from Abstracts

19:00—20:00 Social Hour w/ Lite Bites

19:30—22:00 Poster Session 3

THURSDAY, MARCH 13

07:00—08:00 Breakfast

08:00—11:00 Reservoirs, Latency, Reactivation and Eradication
Registered attendees can view abstracts starting on 02/09/2014

Daria J. Hazuda, Merck Research Laboratories, USA
New Drug Targets in the Search for an HIV Cure

David M. Margolis, University of North Carolina at Chapel Hill, USA
HIV Eradication Approaches

Hiroyu Hatano, University of California, San Francisco, USA
HIV Persistence in "Elite" Controllers

Steven M. Wolinsky, Northwestern University, USA
Latent and Active HIV Reservoirs

Short Talk(s) Chosen from Abstracts


Following Session is for HIV Vaccines: Adaptive Immunity and Beyond (X3)

08:00—11:00 From Concepts to Implementation
Registered attendees can view abstracts starting on 02/09/2014

Nicole Frahm, Fred Hutchinson Cancer Research Center, USA
Phase I and II Vaccine Strategies

Magdalena E. Sobieszczyk, Columbia University, USA
HVTN 505

Jerome H. Kim, Walter Reed Army Institute of Research, USA
RV144 and HIV Acquisition: Insights and New Questions

Thomas C. Quinn, NIAID and Johns Hopkins University, USA
The Impact of Combination Prevention on the HIV Pandemic

Short Talk(s) Chosen from Abstracts

09:20—09:40 Coffee Break

On Own for Lunch and Recreation

14:30—16:30 Workshop 2

Short Talks Chosen from Abstracts

16:30—17:00 Coffee Available

17:00—18:30 Cellular and Genetic Therapies for HIV/AIDS (Joint)
Registered attendees can view abstracts starting on 02/09/2014

Robert F. Siliciano, Johns Hopkins University School of Medicine, USA
Prospects for HIV Eradication

Nicolas Chomont, Vaccine & Gene Therapy Institute of Florida, USA
Eradication

Jerome A. Zack, University of California, Los Angeles, USA
Engineering Human T Cell Immunity

18:30—19:30 Keynote Address (Joint)
Registered attendees can view abstracts starting on 02/09/2014

Mark M. Davis, Stanford University, USA

19:30—20:30 Social Hour w/ Lite Bites

20:00—23:00 Entertainment

FRIDAY, MARCH 14

Departure

9 Mar - 14 Mar 2014
Banff
Canada
meeting website