RNA Silencing

Organized by V. Narry Kim of Seoul National University, David P. Bartel of Massachusetts Institute of Technology and Julius Brennecke of IMBA – Institut für Molekulare Biotechnologie GmbH, the four-day conference will:
• Discuss recent advances in small RNA-mediated gene regulatory pathways;
• Serve as a central forum to discuss the latest information on the development of therapeutics and diagnostics based on RNA silencing for a wide range of human diseases;
• Bridge high-quality basic science on small RNAs with cutting-edge translational research.

+ show speakers and program
Keynote Address
Phillip D. Zamore, University of Massachusetts Medical School, USA

Jennifer A. Doudna, HHMI/University of California, Berkeley, USA
RNA-Programmed Genome Defense by Bacterial CRISPRs

Yi Liu, University of Texas Southwestern Medical Center, USA
Diverse Fungal Small RNA Production Pathways

Elisabetta Ullu, Yale University, USA
Small RNA Machinery in Trypanosoma

Dinshaw J. Patel, Memorial Sloan-Kettering Cancer Center, USA
Structural Insights into Silencing Machineries

Leemor Joshua-Tor, Cold Spring Harbor Laboratory, USA
Structure of Argonaute

Elisa Izaurralde, Max Planck Institute for Developmental Biology, Germany
Mechanism of miRNA-Mediated Silencing

Ian MacRae, The Scripps Research Institute, USA
Structure of Dicer and Argonaute

Antonio J. Giraldez, Yale University School of Medicine, USA
Silencing Mechanism in Zebrafish

V. Narry Kim, Seoul National University, South Korea
Biogenesis and Regulation of microRNA

Xuemei Chen, University of California, Riverside, USA
RNA Silencing Mechanisms in Plants

Eric N. Olson, University of Texas Southwestern Medical Center, USA
MicroRNA in Cardiovascular Diseases

Joshua T. Mendell, University of Texas Southwestern Medical Center, USA
MicroRNA in Cancer

Sonya D. Zabludoff, Regulus Therapeutics, USA
Targeting the Pathways of Human Disease with MicroRNA Therapeutics

Rachel E. Meyers, Alnylam Pharmaceuticals Inc., USA
Developing RNAi Therapeutics for the Treatment of Rare Diseases

Markus Stoffel†, Institute of Molecular Health Science, Switzerland
Talk Title to be Determined

Victor R. Ambros, University of Massachusetts, USA
MicroRNAs in Development and Stress Responses

David P. Bartel, Massachusetts Institute of Technology, USA
Systems Approaches to microRNA

Andrew Fire, Stanford University, USA
Triggers and Limits to Amplification in RNAi

David C. Baulcombe, University of Cambridge, UK
Silencing in Plants

Eric A. Miska, University of Cambridge, UK
Small RNA Biogenesis

Kazufumi Mochizuki, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Austria
Transgenerational Epigenetic Control in Tetrahymena

Gregory J. Hannon, Cold Spring Harbor Laboratory, USA
Small RNAs in Mammalian Germline

Mikiko C. Siomi, University of Tokyo, Japan
piRNA Biogenesis in Insects

Julius Brennecke, IMBA - Institut für Molekulare Biotechnologie GmbH, Austria
piRNA Pathway in Drosophila

William Theurkauf, University of Massachusetts Medical Center, USA
Organization of a Transposon Silencing Compartment

Michael Thomas McManus, University of California, San Francisco, USA
MicroRNA Knockout Mice

Sam Griffiths-Jones, University of Manchester, UK
miRBase, Deep Sequencing, and Arm Switching

31 Jan - 5 Feb 2014
Seattle
United States of America
meeting website