Lysophospholipid and Other Related Mediators - From Bench to Clinic

Lysophospholipid and Other Related Mediators - From Bench to Clinic
+ show speakers and program
Sunday,August 4, 2013
4:00 PM – 9:00 PM Conference Registration
6:00 PM – 7:00 PM FASEB Opening Reception
7:00 PM – 8:30 PM Dinner
8:45 PM – 9:00 PM Welcoming Remarks: Yasuyuki Igarashi (Hokkaido University)
9:00 PM – 9:30 PM Keynote Speaker 1: Gabor Tigyi (University of Tennessee)
“Title of talk”
9:30 PM – 10:00 PM Keynote Speaker 2: Jason Cyster (University of California)
“S1P in lymphocyte egress and confinement”

Monday,August 5, 2013
7:30 AM – 9:00 AM Breakfast
Session 1:
9:00 AM – 12:15 PM
Fundamental aspects of lysophospholipid mediators (I)
Session Chair: Yasuyuki Igarashi (Hokkaido University)
9:00 AM – 9:15 AM Welcome from FASEB
9:15 AM - 9:45 AM Speaker 1, Sara Spiegel, (Virginia Commonwealth University)
“SphK1 and S1PR1 Axis: A Critial Link Between Inflammation
and Cancer”
9:45 AM –10:15 AM Speaker 2, Akira Tokumura, Tokushima University
“New isozymes of lysophospholipase D”
10:15 AM – 10:30 AM Short Talk Selected From Submitted Abstracts
10:30 AM – 11:00 AM Group photo & FASEB Sponsored Coffee Break
11:00 AM – 11:30 AM Speaker 3, Wouter Moolenaar (Netherlands Cancer Institute)
“New insights into Autotaxin structure and function”
11:30 AM – 12:00 PM Speaker 4, Takao Shimizu (University of Tokyo)
“Glycerophospholipid metabolism and biological functions”
12:00 PM – 12:15 PM Short Talk Selected From Submitted Abstracts
12:15 PM – 1:15 PM Lunch
1:15 PM – 3:15 PM Meet the Expert
4:00 PM – 6:00 PM Poster Session 1
6:00 PM – 7:00 PM Dinner
Session 2:
7:00 PM – 9:30 PM
Fundamental aspects of lysophospholipid mediators (II)
Session Chair: Junken Aoki (Tohoku University)
7:00 PM - 7:30 PM Speaker 1, Richard Proia (National Institute of Health)
“In vivo imaging of S1P receptor signaling during pathogenesis”
7:30 PM – 8:00 PM Speaker 2, Yoh Takuwa (Kanazawa University School of
Medicine)
“S1P2 inhibits vascular hyperpermeability through suppressing
endothelial nitric oxide synthase”
8:00 PM – 8:15 PM Short Talk Selected From Submitted Abstracts
8:15 PM – 8:30 PM Break
8:30 PM – 9:00 PM Speaker 3, Masayuki Miyasaka (Osaka University)
“The autotaxin/LPA axis regulates lymphocyte extravasation in
lymph nodes”
9:00 PM – 9:30 PM Speaker 4, Junken Aoki (Tohoku University)
“LPA in blood regulates bagal afferent nerve through LPA3”

Tuesday,August 6, 2013
7:30 AM – 9:00 AM Breakfast
Session 3
9:00 AM – 12:00 PM
Fundamental aspects of lysophospholipid mediators (III)
Session Chair: Julia Saba (Children's Hospital Oakland
Research Institute)
9:00 AM - 9:30 AM Speaker 1, Julia Saba (Children's Hospital Oakland Research
Institute)
“Title of talk”
9:30 PM –10:00 AM Speaker 2, Tsuyoshi Nishi (Osaka University)
“Physiological role of S1P transporters in S1P signaling”
10:00 AM – 10:15 AM Short Talk Selected From Submitted Abstracts
10:15 AM – 10:45 AM FASEB Sponsored Coffee Break
10:45 AM – 11:15 AM Speaker 3, Stefan Offermanns (Leiden University)
“Regulation of metabolic and cardiovascular functions through
GPCRs and downstream signalling pathways”
11:15 AM – 11:45 AM Speaker 4, David Brindley (University of Alberta)
“Mechanisms for regulating lysophosphatidate-induced chemoresistance”
11:45 AM – 12:00 PM Short Talk Selected From Submitted Abstracts
12:00 PM – 1:00 PM Lunch
1:00 PM – 3:00 PM Meet the Expert
4:00 PM – 6:00 PM Poster Session 1
6:00 PM – 7:00 PM Dinner
Session 4:
7:00 PM – 9:30 PM
Fundamental aspects of lysophospholipid mediators (IV)
Session Chair: Akio Kihara (Hokkaido University)
7:00 PM - 7:30 PM Speaker 1, Hsinyu Lee (Institute of Zoology)
“LPA as a regulator for blood cell differentiation”
7:30 PM – 8:00 PM Speaker 2, Atsuo Kawahara (RIKEN)
“Functional analysis of S1P signaling using the TALEN-mediated
genome modification”
8:00 PM – 8:15 PM Short Talk Selected From Submitted Abstracts
8:15 PM – 8:30 PM Break
8:30 PM – 8:45 PM Short Talk Selected From Submitted Abstracts
8:45 PM – 9:15 PM Speaker 3, Akio Kihara (Hokkaido University)
“Identification of a complete sphingosine 1-phosphate metabolic
pathway”
9:15 PM – 9:30 PM Short Talk Selected From Submitted Abstracts

Wednesday,August 7, 2013
7:30AM – 9:00AM Breakfast
Session 5
9:00 AM – 12:00 PM
Fundamental aspects of lysophospholipid mediators (V)
Session Chair: Toshiro Okazaki (Kanazawa Medical University)
9:00 AM - 9:30 AM Speaker 1, Toshiro Okazaki (Kanazawa Medical University)
“Mutual function of S1P with ceramide in autophagic cell death
through mTOR”
9:30 AM –10:00 AM Speaker 2, Jerold Chun (Scripps)
“New insights on lysophospholipid signaling”
10:00 AM – 10:15 AM Short Talk Selected From Submitted Abstracts
10:15 AM – 11:00 AM FASEB Sponsored Coffee Break
11:00 AM – 11:30 AM Speaker 3, Hiroshi Ueda (Nagasaki University)
“Central pain and lysophosphatidic acid”
11:30 AM – 11:45 AM Short Talk Selected From Submitted Abstracts
11:45 AM – 12:00 PM Short Talk Selected From Submitted Abstracts
12:00 PM – 1:00 PM Lunch
Free Afternoon
4:00 PM – 6:00 PM Poster Session 2
6:00 PM – 7:00 PM Dinner
Session 6:
7:00 PM – 9:30 PM
Pathophysiology of lysophospholipid mediators - Cancer -
Session Chair: Lina Obeid (Medical University of South Carolina)
7:00 PM - 7:30 PM Speaker 1, Lina Obeid (Medical University of South Carolina)
“Bioactive sphingolipids in cancer”
7:30 PM – 8:00 PM Speaker 2, Nigel Pyne (University of Strathclyde)
“S1P and cancer”
8:00 PM – 8:15 PM Short Talk Selected From Submitted Abstracts
8:15 PM – 8:30 PM Break
8:30 PM – 8:45 PM Short Talk Selected From Submitted Abstracts
8:45 PM – 9:15 PM Speaker 3, Olivier Peyruchaud (INSERM)
“Title of talk
9:15 PM – 9:30 PM Short Talk Selected From Submitted Abstracts

Thursday,August 8, 2013
7:30 AM – 9:00 AM Breakfast
Session 7
9:00 AM – 12:00 PM
Pathophysiology of lysophospholipid mediators -
Circulation and vasculature –
Session Chair: Susan Smyth (University of Kentucky)
9:00 AM - 9:30 AM Speaker 1, Susan Smyth (University of Kentucky)
“Title of talk
9:30 PM –10:00 AM Speaker 2, Roger Sabbadini (Lpath, Inc.)
“Clinical development of therapeutic antibodies to S1P and LPA”
10:00 AM – 10:15 AM Short Talk Selected From Submitted Abstracts
10:15 AM – 10:45 AM FASEB Sponsored Coffee Break
10:45 AM – 11:15 AM Speaker 3, Satoshi Nishimura (University of Tokyo)
“Contributin of autotaxin to metabolic diseases in human and
mice”
11:15 AM – 11:45 AM Speaker 4, Jody Rosenblatt (University of Utha)
“Title of talk”
11:45 PM – 12:00 PM Short Talk Selected From Submitted Abstracts
12:00 PM – 12:30 PM Business Meeting
12:30 PM – 1:30 PM Lunch
Free Afternoon
1:00 PM – 6:00 PM Optional Organized Group Activity
4:00 PM – 6:00 PM Poster Session 2
6:00 PM – 7:00 PM Dinner
Session 8:
7:00 PM – 9:30 PM
Pathophysiology of lysophospholipid mediators - Immunity
and inflammation -
Session Chair: Takehiko Yokomizo (Juntendo University)
7:00 PM - 7:30 PM Speaker 1, Takehiko Yokomizo (Juntendo University)
“Inflammatory and anti-inflammatory roles of leukotriene
receptors”
7:30 PM – 8:00 PM Speaker 2, Kenji Chiba (Mitsubishi Tanabe Pharma Corporation)
“Discovery of fingolimod (FTY720), the sphingosine 1-phosphate
receptor modulator and its application for the therapy of multiple
sclerosis”
8:00 PM – 8:15 PM Short Talk Selected From Submitted Abstracts
8:15 PM – 8:30 PM Break
8:30 PM – 8:45 PM Short Talk Selected From Submitted Abstracts
8:45 PM – 9:15 PM Speaker 3, Shu Narumiya (Kyoto University)
“Prostaglandins and chronic inflammation”
9:15 PM – 9:30 PM Short Talk Selected From Submitted Abstracts

Friday,August 9, 2013
7:30 AM – 8:30 AM Breakfast
Session 9
8:30 AM – 11:30 PM
New technology in lysophospholipid study
Session Chair: Alfred Merrill (Georgia Institute of Technology)
8:30 AM - 9:00 AM Speaker 1, Alfred Merrill (Georgia Institute of Technology)
“An update on sphingolipidomics and signaling molecules in
food”
9:00 AM – 9:30 AM Speaker 2, Mitsutoshi Seto (Hamamatsu University)
“Imaging Mass Spectrometry of Lipids”
9:30 AM – 9:45 AM Short Talk Selected From Submitted Abstracts
9:45 AM – 10:15 AM Break
10:15 AM – 10:30 AM Short Talk Selected From Submitted Abstracts
10:30 AM – 11:00 AM Speaker 3, Masaru Ishii (Osaka University)
“The role of S1P for controlling migration and function of bone
and immune cells”
11:00 AM – 11:15 AM Short Talk Selected From Submitted Abstracts
11:15 AM – 11:30 AM Closing Comments
11:30 AM Departures
Boxed Lunches Available
END OF CONFERENCE

4 Aug - 9 Aug 2013

Niseko
Japan
meeting website