Autoimmunity

Autoimmunity
+ show speakers and program
Sunday, July 7, 2013
4:00PM – 9:00AM Conference Registration
6:00PM – 7:00 PM FASEB Opening Reception
7:00PM – 8:30 PM Dinner
8:45PM – 10:00PM Keynote Speaker, Dan Kastner, NHGRI, NIH
Dangerous Liaisons: Murphy's Law and Human Immunity

Monday, July 8, 2013
7:30AM – 9:00AM Breakfast
Session 1:
9:00AM – 12:15PM
Genetic and Environmental Interactions in Autoimmunity
Chair: David Hafler
9:00AM – 9:15AM Welcome from FASEB
9:15AM - 9:45AM Tim Behrens, Genentech
SLE - From genetics to therapies
9:45AM –10:15AM Chaim Jacob, USC
Involvement of the superoxide-generating leukocyte NADPH
oxidase in the genetic predisposition to lupus
10:15AM – 10:30 AM Short Talk Selected From Submitted Abstracts
10:30AM – 11:00AM Group photo & FASEB Sponsored Coffee Break
11:00AM – 11:30AM David Hafler, Yale U
From GWAS Genetics to Biology
11:30AM – 12:00PM Christophe Benoist, Harvard U
Genomics of Tolerance
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM Lunch
Free Afternoon
4:00PM – 6:00PM Poster Session 1
6:00PM – 7:00PM Dinner
Session 2:
7:00PM – 9:45PM
B Cells in Autoimmunity
Chair: Mark Shlomchik, Yale University
7:00PM - 7:30PM Mark Shlomchik, Yale University
B vs DC: How to activate T in SLE
7:30PM – 8:00PM Ann Marshak-Rothstein, U Mass Med School
“Title to follow””
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Silvia Bolland, NIH
Chronic innate activation of lymphoid cells in autoimmunity
9:15PM – 9:45PM Joe Craft, Yale University
Follicular Helper T Cells in Immunity and Autoimmunity

Tue, July 9, 2013
7:30AM – 9:00AM Breakfast
Session 3
9:00AM – 12:15PM
Interface Between Innate Immunity and Autoimmunity
Chair: Anne Marshak-Rothstein
9:00AM - 9:30AM Jenny Ting, University of North Carolina
NLRs in immunity and beyond
9:30PM –10:00AM Phillip Yu, Marburg, Germany
Is there a link between nucleic acid sensing TLRs, ERVs and autoimmunity?
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Greg Barton, UC Berkeley
Regulation of endosomal TLRs
11:15PM – 12:00PM Kate Fitzgerald, U. Mass
Regulation of innate immunity by long non-coding RNA
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:45PM Lunch and “Meet the Expert”
Free Afternoon
4:00PM – 6:00PM Poster Session 2
6:00PM – 7:00PM Dinner
Session 4:
7:00PM – 9:45PM
Pathogenic T cell subsets
Chair: Brigitta Stockinger
7:00PM - 7:30PM Dan Cua, Merck
Mechanisms repressing plasticity while promoting stability of
pathogenic Th17 cells
7:30PM – 8:00PM Alessandra Pernis, Hosp for Special Surgery, NY
“Title to follow ”
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Casey Weaver University of Alabama at Birmingham
IL10 Gene Regulation in Autoimmunity
9:15PM – 9:45PM Brigitta Stockinger, MRC Mill Hill
The17 cell plasticity- expanding the repertoire

Wed, July 10, 2013
7:30AM – 9:00AM Breakfast
Session 5
9:00AM – 12:15PM
Tissue-Specific Regulation of Autoimmunity
Chair : Rachel Caspi
9:00AM - 9:30AM Nathan Karin, Weizman, Israel
The role of chemokines in directing the polarization and
biological functions of regulatory T cells
9:30PM –10:00AM Rachel Caspi, NEI, NIH
NK–DC interaction regulates the Th17 response through
an innate IFN-γ/IL-27 axis
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Thomas Kupper, Harvard
Skin Immunity 2013—a new role for T cells
11:15PM – 12:00PM Joan Goverman, Univ. Washington
Differential Responses to Inflammation Within Distinct
Microenvironments of the Central Nervous System
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM Lunch
Free Afternoon
6:00PM – 7:00PM Dinner
Session 6:
7:00PM – 9:45PM
Tregs and Autoimmunity
Chair: Ethan Shevach
7:00PM - 7:30PM Kenya Honda, Tokyo University and RIKEN (RCAI) Japan
Regulation of T cells by the gut microbiota
7:30PM – 8:00PM Jeff Bluestone, UCSF
Mechanisms of IL-2 driven Treg stability and their role in control
of autoimmunity
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM Ethan Shevach, NIAID, NIH
Modulation of Dendritic Cell Function by T Regulatory Cells
9:15PM – 9:45PM Dario Vignali, St. Jude Childrens Research
Molecular Control of Treg Stability and Function

Thu, July 11, 2013
7:30AM – 9:00AM Breakfast
Session 7
9:00AM – 12:15PM
Immunoregulatory Circuits
Chair: Fiona Powrie
9:00AM - 9:30AM Charles Egwuagu, NEI, NIH
“Title to follow”
9:30PM –10:00AM Amit Bar-Or, McGill
'Closing the Loop: Human B cells and Immune Regulation’
10:00AM – 10:15AM Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM FASEB Sponsored Coffee Break
10:45AM – 11:15PM Fiona Powrie, Oxford U, UK
“Title to follow””
11:15PM – 12:00PM Arlene Sharpe, Harvard Medical School
The multifaceted roles of the PD-1 pathway in regulating T cell
activation
12:00PM – 12:15PM Short Talk Selected From Submitted Abstracts
12:15PM – 12:45PM Business Meeting
12:45PM – 1:45PM Lunch
Free Afternoon
1:00PM – 6:00PM Optional Organized Group Activity
4:00PM – 6:00PM Poster Session 4 – Optional
6:00PM – 7:00PM Dinner
Session 8:
7:00PM – 9:45PM
Targeted Therapy for Autoimmune Diseases
Chair: Jeff Bluestone
7:00PM - 7:30PM David Scott, USUHS
From gene therapy to IgG fusion proteins and specific
Tregs:Novel therapies for tolerance induction
7:30PM – 8:00PM ”Herman Waldmann, Oxford
Therapeutic approaches to promote regulation
8:00PM – 8:15PM Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM Break
8:30PM – 8:45PM Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM James Clark, Pfizer
“Title to follow
9:15PM – 9:45PM Dhaval Patel, Novartis
Effect of IL-17A blockade in autoimmune diseases.

Friday, July 12, 2013
7:30AM – 8:30AM Breakfast
8:30AM – 9:30AM Closing Comments
9:30AM Departures
Boxed Lunches Available
END OF CONFERENCE

7 Jul - 12 Jul 2013

Saxtons River
United States of America
meeting website