Renal Hemodynamics: Integrating with the nephron and beyond

Renal Hemodynamics: Integrating with the nephron and beyond
+ show speakers and program
Sunday,June 30, 2013
4:00PM – 9:00PM Conference Registration
6:00PM – 7:30 PM Dinner
7:30PM – 8:20PM Keynote Speaker, Tom Coffman, Duke University
“How to bridge the gap between basic and clinical science, the art
of translation using animal models”

Monday,July 1, 2013
7:00AM – 8:00AM Breakfast
8:00AM – 8:30AM Introduction and Orientation
Session 1:
8:30AM – 10:10AM
Hemodynamics in Renal Failure
Session Chair, Pontus Persson, Charite University of Berlin
8:30AM - 8:55AM Jan Menne, Medizinische Hochschule Hannover
“Interaction of GFR and Albuminuria in the ROADMAP study
8:55AM –9:20AM Pontus Persson, Charite University of Berlin
“Causes of acute kidney injury by contrast media”
9:20AM – 9:45AM Erika Boesen, University of Nebraska
“Renal hemodynamic consequences of acute kidney injury”
9:45AM – 10:10AM Speaker selected from submitted abstracts
10:10AM – 10:30AM Group photo & FASEB Sponsored Coffee Break
Session 2:
10:40AM – 11:55AM
Pathogenesis of renal dysfunction in hypertension
Marcela Herrera, Duke University
10:30AM – 10:55AM Ken Mitchell, Tulane University
“Renal Functional Responses to Selective Intrarenal Renin
Inhibition in Cyp1a1-Ren2 Transgenic Rats with ANG II-Dependent
Malignant Hypertension”
10:55AM – 11:20AM Jan Williams, University of Mississippi
“The Involvement of MMPs in the Control of Glomerular
Permeability”
11:20AM – 11:45AM Jennifer Sullivan, Georgia Regents University
“Ang (1-7) protects against Ang II-induced renal injury”
11:45AM – 12:10PM Aaron Polichnowski, Loyola University
“Hypertension induced renal injury”
12:15PM – 1:15PM Lunch
Free Afternoon
6:00PM – 7:30PM Dinner
Session 3:
7:30PM – 9:10PM
A New Look at the Kidney
Session Chair, Will Cupples, Simon Fraser University
7:30PM - 7:55PM Niels-Henrik Holstein-Rathlou, Copenhagen
“Nephron dynamics and the renal vascular network”
7:55PM – 8:20PM Janos Peti-Peterdi, University of Southern California
“Tracking the fate of renal cell types in vivo using serial multiphoton
imaging in novel mouse models with fluorescent lineage tags”
8:20PM – 8:45PM Lilach Lerman, Mayo Clinic
“Obesity in renovascular disease: Friend or Foe”
8:45PM – Poster Session 1

Tuesday,July 2, 2013
7:00AM – 8:30AM Breakfast
Session 4
8:30AM – 10:10AM
Diabetes, Obesity, and Glomerular Function
Session Chair, Christine Maric, University of Mississippi
8:30AM - 8:55AM Volker Vallon, University of California San Diego
“Proximal tubular transport in the diabetic kidney”
8:55PM – 9:20AM Fredrik Palm, Linköping University
“Oxidative stress and nitric oxide in diabetes”
9:20AM – 9:45AM Adam Whaley-Connell, University of Missouri
“Novel implications for Ang II in obesity related salt-sensitivity”
9:45AM – 10:10AM Speaker selected from submitted abstracts
10:10AM – 10:30AM FASEB Sponsored Coffee Break
Session 5
10:30AM – 12:10PM
The Renal Medulla
Session Chair, Tom Pallone, University of Maryland
10:30AM – 10:55AM Mauricio Sendeski, Charité Medical University, Berlin,
Germany
“The role of osmolarity and pressure in the modulation of
vasoactivity of isolated perfused human vasa recta”
10:55AM – 11:20AM Tom Pallone, University of Maryland
“Cardiac Glycosides and Renal Medullary Function”
11:20AM – 11:45AM Peter Bie, University of Southern Denmark
“Cortical and medullary blood flows in patients with essential
hypertension”
11:45AM – 12:10PM Claire Peppiatt-Wildman, The Universities of Kent and Greenwich
at Medway
“The role of medullary pericytes in drug-induced nephrotoxicity”
12:15PM – 1:15PM Lunch
Free Afternoon
Session 6:
5:00PM – 6:00PM
Special Session 1
Session Chair, Jane Reckelhoff, University of Mississippi
5:00PM – 5:25PM Featured Topic, Curt Sigmund, University of Iowa
“Regulation of Vasomotor Function by Novel PPARG Target
Genes”
5:25PM – 6:00PM DATA DIURESIS, 5 min talks, limit 2 slides
6:00PM – 7:00PM Dinner with the Professor
Session 7:
7:30PM – 9:10PM
Novel Cellular Pathways
Session Chair, Fredrik Palm, Linköping University
7:30PM - 7:55PM Armin Kurtz, University of Regensberg
“Role of von Hippel Lindau protein for differentiation of for renin
expressing cells”
7:55PM – 8:20PM Lisa Harrison-Bernard, Louisiana State University
“Targeting Chymase in Diabetic Nephropathy”
8:20PM – 8:45PM Romer Gonzalez-Villalobos, Cedars-Sinai.
“Role of renal ACE in hypertension”
8:45PM – 9:10PM Dominique Charmot, Ardelyx Corp.
“Therapeutic application of gut-acting, minimally systemic NHE3
inhibitors”

Wednesday,July 3, 2013
7:00AM – 8:30AM Breakfast
Session 8
8:30AM – 10:10AM
Hypoxia, Ischemia, and Renal Injury
Session Chair, David Basile, Indiana University
8:30AM - 8:55AM Kevin Burns, University of Ottawa
“Angiotensin-converting enzyme 2 and its cleavage in the kidney
proximal tubule”
8:55PM – 9:20AM David Basile, Indiana University
“Abnormal repair and immune responses on acute kidney injury
transition to chronic kidney disease”
9:20AM – 9:45AM Prabhleen Singh, University of California San Diego
“Renal oxygenation in the pathophysiology of kidney disease”
9:45AM – 10:10AM Daisuke Nakano, Kagawa University
“Contribution of p21-dependent cell cycle regulation to acute kidney
injury”
10:10AM – 10:30AM FASEB Sponsored Coffee Break
Session 9
10:30AM – 12:10PM
Reactive Oxygen Species
Session Chair, William Welch, Georgetown University
10:30AM – 10:55AM William Welch, Georgetown University
“Reactive Oxygen Species in Hypertension: Cause or Effect?”
10:55AM – 11:20AM Reiko Inagi, University of Tokyo
“Oxidative and glycative stress: a culprit of renal hemodynamics”
11:20AM – 11:45AM Paul O’Connor, Georgia Regents University
“HVCN1 drives superoxide production in the medullary thick
ascending limb”
11:45AM – 12:10PM Sergey Smirnov, University of Bath
“Voltage-activated calcium channels in the renal microvasculature:
patch-clamp studies in native myocytes isolated from single afferent
and efferent arterioles”
Free Afternoon
6:00PM – 7:00PM Dinner
Session 10:
7:30PM – 9:10PM
Renal Inflammation
Session Chair, Roger Evans, Monash University
7:30PM - 7:55PM Dominik Mueller, Charite University of Berlin
“Target organ damage”
7:55PM – 8:20PM Michael Ryan, University of Mississippi
“Lupus and renal inflammation”
8:20PM – 8:45PM Branko Braam, University of Alberta
“Reduced kidney function, Inflammation, circulating cells, salt and
the RAS: a hot soup”
8:45PM – Poster Session 2

Thursday,July 4, 2013
7:00AM – 8:30AM Breakfast
Session 11
8:30AM – 10:10AM
Autoregulation, TGF, and Myogenic Control
Session Chair, Scott Thomson, University of California San Diego
8:30AM - 8:55AM Anita Layton, Duke University
“Mathematical Modeling of Renal Hemodynamics”
8:55PM – 9:20AM Pernille Hansen, University of Southern Denmark
“News about renal function and T-type calcium channels learned
from knock-out models”
9:20AM – 9:45AM Ed Inscho, Georgia Regents University
“Insights into autoregulatory dysfunction”
9:45AM – 10:10AM Mattias Carlstrom, Uppsala University
“Interaction between adenosine, superoxide and nitric oxide in
regulating tubuloglomerular feedback”
10:10AM – 10:30AM FASEB Sponsored Coffee Break
Session 12
10:30AM – 12:10PM
Mediators in Blood Pressure Control
Session Chair, Michel Schwartzman, New York Medical College
10:30AM – 10:55AM Josh Speed, Georgia Regents University
“Endothelin regulation of blood pressure and sodium homeostasis”
10:55AM – 11:20AM Marcela Herrera, Duke University
“Contribution of ETB receptors in the Thick Ascending Limb to
blood pressure regulation”
11:20AM – 11:45AM David Stec, University of Mississippi
“Renal Heme oxygenase and its metabolites in the regulation of
blood pressure”
11:45AM – 12:10PM Lise Bankir, Inserm, Paris
“Role of glucagon, vasopressin and urea in the regulation of GFR.
A new hypothesis”
12:15PM – 1:15PM Lunch
Free Afternoon
Session 13:
5:00PM – 6:00PM
Special Session 2
Session Chair, Takefumi Mori, Tohoku University
5:00PM – 5:25PM Featured Topic, Sadayoshi Ito, Tohoku University
“Cardirenal syndrome and medullary circulation”
5:25PM – 6:00PM DATA DIURESIS, 5 min talks, limit 2 slides
6:00PM – 7:00PM Dinner with the Professor
Session 14:
7:30PM – 9:10PM
Sodium Homeostasis
Session Chair, Jeff Garvin, Cleveland Clinic
7:30PM - 7:55PM Pablo Ortiz, Henry Ford Hospital
“NO and cGMP signaling in thick ascending limbs: Role in salt
sensitive hypertension”
7:55PM – 8:20PM Alicia McDonough, University of Southern California
“Integrated regulation of transporters along the nephron to maintain
electrolyte and fluid homeostasis”
8:20PM – 8:45PM Jens Titze, Vanderbilt University
“Homeostatic immune cells control local lymphatic electrolyte
clearance”
8:45PM – 9:10PM Speaker chosen from submitted abstracts

Friday,July 5, 2013
7:00AM – 8:30AM Breakfast
Session 15
8:30AM – 10:10AM
Epigenetics and Age-Dependent Mechanisms
Session Chair, Jennifer Sullivan, Georgia Regents University
8:30AM - 8:55AM Analia Loria, Georgia Regents University
“Impact of Early life stress on the renal phenotype: potential role of
the epigenome”
8:55PM – 9:20AM Kate Denton, Monash University
“Role of the depressor arm of the RAS in pregnancy”
9:20AM – 9:45AM Heddwen Brooks, University of Arizona
“Hypertension, menopause and kidney inflammation”
9:45AM – 10:10AM Business Meeting
10:10AM – 10:30AM FASEB Sponsored Coffee Break
Session 16
10:30AM – 12:15PM
Renal Mechanisms of Angiotensin Action
Session Chair, Lisa Harrison-Bernard, Louisiana State University
10:30AM – 10:55AM Jan Wysocki, Northwestern University
“Urinary ACE2 in control and diabetic mice”
10:55AM – 11:20AM Mark Chappell, Wake Forest University
“Renal Angiotensin-(1-12) and Salt-Sensitive Hypertension”
11:20AM – 11:45AM Matthew Zimmerman, University of Nebraska
“Oxidants, Antioxidants, and Hypertension: It’s All in Your Head”
11:45AM – 12:10PM Radu Iliescu, University of Mississippi
“The benefits of unsteadiness: Cardiovascular dynamics during
carotid baroreflex activation”
12:10PM – 12:15PM Closing Comments
12:30PM Departures
Boxed Lunches Available
END OF CONFERENCE

30 Jun - 5 Jul 2013

Saxtons River
United States of America
meeting website