Biology of Cilia and Flagella

Biology of Cilia and Flagella
+ show speakers and program
Sunday June 23, 2013
4:00PM – 9:00AM
Conference Registration
6:00PM – 7:00 PM
FASEB Opening Reception
7:00PM – 8:30 PM
Dinner
8:45PM – 10:00PM
Keynote Speaker Wallace Marshall (University of CA, San Francisco)
How Cells Measure - the Flagellar Length Control System

Monday June 24, 2013
7:30AM – 9:00AM
Breakfast
Session 1:
9:00AM – 12:15PM
Function of Cilia in Kidney Development and Polycystic Kidney Disease
Session Chair Rebecca Burdine (Princeton University)
9:00AM – 9:15AM
Welcome from FASEB
9:15AM - 9:45AM
Peter Harris (Mayo Clinic, Rochester MN)
Understanding Pathogenesis in ADPKD
9:45AM –10:15AM
Iain Drummond (Nephrology Division, MGH, Boston MA)
Expanded roles for cilia in kidney development.
10:15AM – 10:30 AM
Short Talk Selected From Submitted Abstracts
10:30AM – 11:00AM
Group photo & FASEB Sponsored Coffee Break
11:00AM – 11:15AM
Caplan Lab (Yale School of Medicine)
11:15PM – 11:30AM
Short Talk Selected From Submitted Abstracts
11:30AM – 12:00PM
Xuefeng Su (Zhou Lab, Harvard Medical)
The role of the BBSome in trafficking polycystin-1 to cilia
12:00PM – 12:15PM
Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM
Lunch
Session 2:
1:30-3:45
Ciliary Signal Transduction
Session Chair Sakait Mukhopadhyay (UT Southwestern Medical Center)
1:30PM - 2:00PM
Peter Satir (AECOM)
Consequences of PDGFRa signaling for cell migration
2:00PM - 2:30PM
Saikat Mukhopadhyay (Cell Biology, UT Southwestern)
GPCRs, Hedgehog Signaling, and Cilia
2:30PM - 2:45PM
Break
2:45PM - 3:15PM
Oliver Blacque (The Conway Institute, University College Dublin)
Transport mechanisms sculpting C. elegans subciliary membrane compartments
3:15PM-3:45PM
Søren Christensen (University of Copenhagen)
TGF-beta signaling coordinated by clathrin-dependent endocytosis at the pocket of primary cilia
4:00PM – 6:00PM
Poster Session 1
6:00PM – 7:00PM
Dinner
Session 3:
7:00PM – 9:45PM
The Obesity Ciliopathies
Session Chair Oliver Blacque (The Conway Institute, University College Dublin)
7:00PM - 7:30PM
Rudolph Leibel (Columbia University, New York City, NY) The molecular genetics of obesity
7:30PM – 8:00PM
Nicolas Berbari (Yoder Lab, University of Alabama at Birmingham, Birmingham, AL)
Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice
8:00PM – 8:15PM
Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM
Break
8:30PM – 8:45PM
Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM
Alex Loktev (Jackson Lab, Genentech, San Francisco CA)
Ciliary signaling and obesity
9:15PM – 9:45PM
Short Talks Selected From Submitted Abstracts

Tuesday June 25, 2013
7:30AM – 9:00AM
Breakfast
Session 4
9:00AM – 12:15PM
Centrioles and Ciliation
Session Chair Renata Basto (Institut Curie, Paris France)
9:00AM - 9:30AM
Alex Dammermann (Max F. Perutz Laboratories, Vienna, Austria)
Centriole function in C. elegans ciliogenesis
9:30PM –10:00AM
Swadhin Chandra Jana (Bettencourt-Dias Lab, Cell Cycle Regulation Laboratory, Instituto Gulbenkian de Ciência, Oeiras, Portugal)
From centriole to basal body: transition zone assembly in fruit flies
10:00AM – 10:30AM
Renata Basto (Institut Curie, Paris France)
Investigating the role of Bug22 in ciliogenesis
10:30AM – 11:00AM
FASEB Sponsored Coffee Break
11:00AM – 11:30PM
Piali Sengupta (Department of Biology, Brandies University)
A novel role for Girdin in ciliogenesis
11:30PM – 12:00PM
Robert O’Hagan (Barr Lab, Rutgers University)
Role of tubulin post-translational modifications in cilia
12:00PM – 12:15PM
Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM
1:15PM – 2:15PM
Lunch
Meet the Expert
Free afternoon or extra session chosen from abstracts
4:00PM – 6:00PM
Poster Session 2
6:00PM – 7:00PM
Dinner
Session 5:
7:00PM – 9:45PM
Ciliary and Flagellar Motility
Session Chair Triscia Hendrickson (Morehouse College)
7:00PM - 7:30PM
Daniele Nicastro (Department of Biology, Brandeis University, Waltham, MA 02454)
Deconstructing Cilia and Flagella Function with Cryo-Electron Tomography and Structural Proteomics
7:30PM – 8:00PM
Elizabeth Smith (Department of Biological Sciences, Dartmouth College, Hanover, NH 03755)
New insights into the assembly of the ciliary central apparatus
8:00PM – 8:15PM
Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM
Break
8:30PM – 9:15PM
Shorts Talk Selected From Submitted Abstracts
9:15PM – 9:45PM
Rebecca Burdine (Department of Molecular Biology, Princeton University, Princeton, NJ 08544)
Novel Regulators of Ciliary Motility

Wednesday June 26, 2013
7:30AM – 9:00AM
Breakfast
Session 6
9:00AM – 12:15PM
The Transition Zone: Gateway to the Cilium
Session Chair Joel Rosenbaum (Yale University)
9:00AM - 9:30AM
Jeremy Reiter (Department of Biochemistry, University of CA, San Francisco 94158)
Function of the Tectonics
9:30PM –10:00AM
Branch Craige (Witman lab, Department of Cell Biology, University of Massachusetts Medical School)
Cep290 is a structural component of the transition zone
10:00AM – 10:15AM
Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM
FASEB Sponsored Coffee Break
10:45AM – 11:15PM
Bradley Yoder Lab (University of Alabama at Birmingham, Birmingham, AL 35294),
Novel components of the transition zone
11:15PM – 11:45
Dennis Deiner and Chris Wood (Rosenbaum lab, Yale)
New aspects of cilia cell biology: The transition zone: its isolation & analysis; bioactive vesicles released from the ciliary tip
11:45 – 12:15PM
Michel R. Leroux (Simon Fraser University, Burnaby, B.C. Canada)
Organization and function of the transition zone, a ciliary gate
12:15PM – 1:15PM
Lunch
Free afternoon or extra session chosen from abstracts
4:00PM – 6:00PM
Poster Session 3
6:00PM – 7:00PM
Dinner
Session 7:
7:00PM – 9:45PM
Structural Biology of the IFT Particle
Session Chair Esben Lorentzen (Biochemistry, Max Planck Institute)
7:00PM - 7:30PM
Esben Lorentzen (Biochemistry, Max Planck Institute),
Intraflagellar transport proteins IFT74 and IFT81 contain a tubulin-binding module required for ciliogenesis
7:30PM – 8:00PM
Short Talks Selected From Submitted Abstracts
8:15PM – 8:30PM
Break
8:30PM – 8:45PM
Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM
Thibaut Eguether (Pazour Lab, University of Massachusetts Medical School, Worcester MA)
Ift25 and Ift27 maintain the ciliary signaling compartment
9:15PM – 9:45PM
Short Talks Selected From Submitted Abstracts

Thursday June 27, 2013
7:30AM – 9:00AM
Breakfast
Session 8
9:00AM – 12:15PM
Cilia in Heart Development, Left-Right Signaling and More
Session Chair: Dominic Norris (MRC Harwell)
9:00AM - 9:30AM
Sigolène Meilhac (Developmental Biology, Institute Pasteur)
Cell coordination underlying the growth of the developing heart
9:30PM –10:00AM
Cecilia Lo (Developmental Biology, University of Pittsburgh)
Role of the cilia in left-right patterning and congenital heart disease
10:00AM – 10:15AM
Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM
FASEB Sponsored Coffee Break
10:45AM – 11:15PM
Kathryn Anderson lab (Memorial Sloan-Kettering Cancer Center)
Function of cilia and centrioles in early mouse development
11:15PM – 11:30AM
Jonathan Eggenschwiler (University of Georgia, Athens Georgia)
Identification of new genes affecting the ciliary membrane
11:30AM – 12:00PM
Dominic Norris (Mammalian Genetics Unit, MRC Harwell, Oxforshire OX11 ORD UK)
Cilia and cardiac development
12:00PM – 12:15PM
Short Talk Selected From Submitted Abstracts
12:15PM – 12:45PM
Business Meeting
12:45PM – 1:45PM
Lunch
Free afternoon or extra session chosen from abstracts
1:00PM – 6:00PM
Optional Organized Group Activity
4:00PM – 6:00PM
Poster Session 4
6:00PM – 7:00PM
Dinner
Session 9:
7:00PM – 9:45PM
Bardet Biedl Syndrome
Session Chair Peter Satir (Einstein College of Medicine, Bronx, New York 10461)
7:00PM - 7:30PM
Maxence Nachury (Department of Molecular and Cellular Physiology, Stanford School of Medicine, Stanford, CA)
Studying ciliary transport in vitro with permeabilized cells
7:30PM – 8:00PM
Karl Lechtrek (University of Georgia, Athens Georgia)
In vivo analysis of axonemal protein transport in Chlamydomonas cilia
8:00PM – 8:15PM
Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM
Break
8:30PM – 8:45PM
Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM
Val C. Sheffield (Dept. of Pediatrics, Division of Medical Genetics, Univ. of Iowa, Iowa City, IA 52242),
BBS genes in human development and disease
9:15PM – 9:45PM
Nicholas Katsanis (Departments of Cell Biology and Pediatrics, Duke University, Durham, NC)
The mutational load of the IFT particle in ciliopathies

Friday June 28, 2013
7:30AM – 8:30AM
Breakfast
Session 10
8:30AM – 11:30PM
The Human Ciliopathies
Session Chair: Heleen Arts (Department of Human Genetics, Radboud University Nijmegen Medical Centre)
8:30AM - 9:15AM
Short Talk Selected From Submitted Abstracts
9:15AM – 9:30AM
Short Talk Selected From Submitted Abstracts
9:00AM – 9:30AM
Friedhelm Hildebrandt (Boston Children’s Hospital/Harvard)
Nephronophthisis
9:30AM – 9:45AM
Short Talk Selected From Submitted Abstracts
9:45AM – 10:00AM
Break
10:00AM – 10:15AM
Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM
Sophie Saunier (Inserm, Paris France 75015)
The role of cilia in structural birth defects
10:45AM – 11:15PM
Heleen Arts (Department of Human Genetics, Radboud University Nijmegen Medical Centre)
Genetics and pathobiology of complex ciliopathies affecting the kidney
11:15AM – 11:30AM
Closing Comments
11:30AM
Departures
Boxed Lunches Available
END OF CONFERENCE

23 Jun - 28 Jun 2013

Niagara Falls
United States of America
meeting website