Regulation and Function of Small GTPases

Regulation and Function of Small GTPases
+ show speakers and program
Sunday June 2, 2013
4:00PM – 9:00AM
Conference Registration
6:00PM – 7:00 PM
FASEB Opening Reception
7:00PM – 8:30 PM
Dinner
8:45PM – 10:00PM
Keynote Talk
Frank McCormick, UCSF

Monday June 3, 2013
7:30AM – 9:00AM
Breakfast
Session 1:
9:00AM – 12:15PM
Compartmentalized Signaling I
Dafna Bar Sagi, NYU Langone Medical Center
9:00AM – 9:15AM
Welcome from FASEB
9:15AM - 9:45AM
Mark R. Philips, NYU School of Medicine
The complexity of Ras signaling
9:45AM –10:15AM
John Hancock, University of Texas Medical School at Houston
Plasma membrane nanostructure and signal transduction
10:15AM – 10:30 AM
Short Talk Selected From Submitted Abstracts
10:30AM – 11:00AM
Group photo & FASEB Sponsored Coffee Break
11:00AM – 11:30AM
Marino Zerial, Max Planck Institute of Molecular Cell Biology and Genetics
Regulation of trafficking by Rab proteins
11:30AM – 12:00PM
Two Short Talks Selected From Submitted Abstracts
12:15PM – 1:15PM
Lunch
Free Afternoon
4:00PM – 6:00PM
Poster Session 1 – Optional
6:00PM – 7:00PM
Dinner
Session 2:
7:00PM – 9:45PM
Compartmentalized Signaling II
Erik Sahai, UK London Research Institute
7:00PM - 7:30PM
Keynote Talk
Alan Hall, Memorial Sloan Kettering Cancer Center
7:30PM – 8:00PM
Keith Burridge, University of North Carolina, School of Medicine
Mechanical signals to Rho GTPases
8:00PM – 8:15PM
Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM
Break
8:30PM – 8:45PM
Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM
Denise Montell, The John Hopkins University of Medicine
Engineering localized Rac activity in vivo
9:15PM – 9:45PM
Philip Chavrier, Institute Curie
Rab proteins and localized protease delivery

Tuesday June 4, 2013
7:30AM – 9:00AM
Breakfast
Session 3
9:00AM – 12:15PM
Biology driven by specific effector pathways
Deborah Morrison, NCI-Frederick
9:00AM - 9:30AM
Kevin Shannon, University of California, San Francisco
Dissecting the importance of Ras effector pathways using mouse models
9:30PM –10:00AM
Brendan D. Manning, Harvard School of Public Health
Deconstructing Rheb signaling in disease
10:00AM – 10:15AM
Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM
FASEB Sponsored Coffee Break
10:45AM – 11:15AM
Channing Der, Lineberger Comprehensive Cancer Center
Ral or RHO insights TBD
11:15AM – 12:00PM
Ed Manser, Institute of Medical Biology, Singapore
Rho GTPases and effector pathways in Stem Cells
12:00PM – 12:15PM
Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM
1:15PM – 2:15PM
Lunch
Meet the Expert
Free Afternoon
4:00PM – 6:00PM
Poster Session 2 – Optional
6:00PM – 7:00PM
Dinner
Session 4:
7:00PM – 9:45PM
Cell migration and polarity
Ed Manser, Institute of Medical Biology, Singapore
7:00PM - 7:30PM
Keynote Talk
Chris Marshall, ICR London
Title tbc
7:30PM – 8:00PM
Johanna Ivaska, University of Turku
Rab proteins in migration and mitosis
8:00PM – 8:15PM
Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM
Break
8:30PM – 8:45PM
Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM
Kozo Kaibuchi, Nagoya University
Small GTPases and cell polarity
9:15PM – 9:45PM
Anne Ridley, Kings College London UK
Rho proteins and leukocyte migration

Wednesday June 5, 2013
7:30AM – 9:00AM
Breakfast
Session 5
Deconstructing the role of small GTPases in cancer
9:00AM – 12:15PM
Michael A. White, UT Southwestern Medical Center
9:00AM - 9:30AM
Dafna Bar Sagi, NYU Langone Medical Center
Ras signaling in pancreatic cancer
9:30PM –10:00AM
Kevin Haigis, Massachusetts General Hospital
Novel mechanisms of Ras regulation
10:00AM – 10:15AM
Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM
FASEB Sponsored Coffee Break
10:45AM – 11:15AM
Christopher Counter, Duke University Medical Center
RAS isoforms in cancer
11:15PM – 11:45AM
11.45AM – 12:00PM
Joe Kissil, Wistar Institute
The biology of Rac in cancer
Short Talk Selected From Submitted Abstracts
12:15PM – 1:15PM
Lunch
Free Afternoon
4:00PM – 6:00PM
Poster Session 3 – Optional
6:00PM – 7:00PM
Dinner
Session 6:
7:00PM – 9:45PM
Structure, interactions, and biological probes
Denise Montell, John Hopkins School of Medicine
7:00PM - 7:30PM
Keynote Talk
Deborah Morrison, NCI-Frederick
Regulation of the RAS/RAF/ERK pathway via signaling scaffolds
7:30PM – 8:00PM
Helen Mott, University of Cambridge
Structural insights into Cdc42 and ACK
8:00PM – 8:15PM
Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM
Break
8:30PM – 8:45PM
Short Talk Selected From Submitted Abstracts
8:45PM – 9:15PM
Jacqueline Cherfils, Centre national de la recherche scientifique
How to inhibit GEFs
9:15PM – 9:45PM
Klaus Hahn, UNC School of Medicine
Imaging small GTPase activity

Thursday June, 6 2012
7:30AM – 9:00AM
Breakfast
Session 7
9:00AM – 12:15PM
Function of GTPase regulatory proteins
Helen Mott, University of Cambridge
9:00AM - 9:30AM
Angeliki Malliri, Paterson Institute for Cancer Research
Regulation of Tiam1 in Metastasis
9:30PM –10:00AM
Linda Van Aelst, Cold Spring Harbor Laboratory
Regulation of neural development by Rho GTPases
10:00AM – 10:15AM
Short Talk Selected From Submitted Abstracts
10:15AM – 10:45AM
FASEB Sponsored Coffee Break
10:45AM – 11:15PM
Larry Feig, Sackler School of Graduate Biomedical Sciences, Tufts University
GRPs in development
11:15PM – 12:00PM
Xosé R. Bustelo, Centro de Investigación del Cáncer
The biology and function of VAV
12:00PM – 12:15PM
Short Talk Selected From Submitted Abstracts
12:15PM – 12:45PM
Business Meeting
12:45PM – 1:45PM
Lunch
Free Afternoon
1:00PM – 6:00PM
Optional Organized Group Activity
4:00PM – 6:00PM
Poster Session 4 – Optional
6:00PM – 7:00PM
Dinner
Session 8:
7:00PM – 9:45PM
Signaling networks and targets
Kevin Haigis, Massachusetts General Hospital
7:00PM - 7:30PM
Keynote Talk
Joseph Schlessinger, Yale University
Title tbc
7:30PM – 8:00PM
Karen Cichowski, Brigham and Women’s Hospital and Harvard Medical School
Targeting Ras-driven tumors
8:00PM – 8:15PM
Short Talk Selected From Submitted Abstracts
8:15PM – 8:30PM
Break
8:30PM – 8:45PM
John Chernoff, Fox Chase Cancer Center
The biology and targetability of the PAK
8:45PM – 9:15PM
Alejandro Sweet-Cordero, Stanford University School of Medicine
Synthetic lethal interactions with onogenic KRAS
9:15PM – 9:45PM
Michael A. White, UT Southwestern Medical Center
Therapeutic targeting of effector networks

Friday June 6, 2013
7:30AM – 8:30AM
Breakfast
9.00AM
Depart

2 Jun - 7 Jun 2013

Steamboat Springs
United States of America
meeting website