10th International RNAi, MicroRNAs & Single Cell Biology -2013 Meeting

10th International RNAi, MicroRNAs & Oligos-Boston-2013 Meeting
on RNA interference & MicroRNAs: Biochemistry to Drugs & Therapeutics
The Unique Theme to Combine Gene Silencing with Oligo Therapeutics!

Key Sessions
The Genetics of RNAi and microRNAs
RNAi, Oligos delivery in vivo, in vitro
microRNAs and their diverse roles in biology & disease
Computational and Disease Biology of miRNAs
Chemical synthesis of peptides and oligos
Large scale manufacturing and process development
Drug Target identification and Validation
High throughput genome-wide screenings
Development of Oligos and Peptide as Therapeutics
Clinical Application of Oligos and Peptides

Third International Single Cell Biology & Real-Time PCR-Boston-2013 Meeting on
Single Molecule Detection to Amplification & Molecular Imaging
The Unique Theme to Combine Biology & Chemistry with Microfluidics!

Key Sessions
Single Molecule Biology & RTPCR Assays
Single cell qPCR in Stem cells, tumor cells
Fluorescence Spectroscopy & Correlation Microscopy
Single Molecule Genomics
Atomic (Single Molecule) Force Microscopy
Bioscrening, Microfluidics, Fluorescence in Living cells
High throughput qPCR & Chip-integrated platforms
Fluorescent proteins and in vivo Analysis
Imaging gene expression in living cells at single molecule level
+ show speakers and program
AGENDA/SPEAKERS
Wendnesday, May 1, 2013
8:00 A.M: Registration Open
9.00 AM – 6.00 PM Scientific Sessions

Thursday, May 2, 2013
8 A.M: Registration Open
9:00 – 1:00 PM: Scientific Sessions

Keynote Speakers:

Alexander Schier, PhD.
Professor of Molecular & Cellular Biology
Harvard University
Cambridge, MA, USA
Title: Non-coding RNAs as regulators of zebrafish embryogenesis

Rachel Meyers, PhD.
Vice President Research & RNAi Lead Development
Alnylam Pharmaceuticals, Inc.
Cambridge, MA, USA
Title: RNAi Therapeutics: From Discovery to Clinical Development

Other Speakers:

Thomas Duchaine, PhD.
Associate Professor of Biochemistry
Goodman Cancer Center-McGill University
Montreal, Quebec, Canada
Title: A non-canonical site unveils multiple cooperative mechanisms in microRNA-mediated silencing

Laura Sepp-Lorenzino, PhD.
Senior Director of RNA Therapeutics
Merck Research Laboratories
West Point, Pennsylvania, USA
Title: Optimization of lipid nanoparticles and siRNA conjugates for enablement of siRNA therapeutics

Pål Sætrom, DPhil.
Professor of Bioinformatics
Norwegian University of Science & technology
Trondheim, Norway
Title: Noncoding RNA-based regulation

Daniel G. Anderson, PhD.
Associate Professor of Chemical Engineering
David H. Koch Institute for Integrative Cancer Research
Massachusetts Institute of Technology
Cambridge, MA, USA
Title: Combinatorial development of synthetic siRNA delivery systems

Thou Pederson, PhD.
Vitold Arnett Professor of Biochemistry & Molecular Pharmacology
University of Massachusetts Medical School
Worcester MA, USA
Title: MicroRNAs and messenger RNAs in the Nucleolus

Jitendran Muthuswamy, PhD.
Associate Professor of Biomedical Engineering
Arizona State University
Tempe, Arizona, USA
Title: siRNA delivery using microelectrode arrays

Alla Grishok, PhD.
Assistant Professor of Molecular Biophysics
Columbia University-College of Physicians & Surgeons, New York, New York, USA
Title: Gene regulation by endogenous RNAi in C. elegans

Fabien Florent Pinaud, PhD.
Assistant Professor of Biological Sciences & Chemistry
University of Southern California
Los Angeles, CA, USA
Title: Targeting and tracking of individual proteins in live animals with nanometer accuracy

Shusheng Wang, PhD.
Assistant Professor
Tulane University
New Orleans, LA, USA
Title: Functional study of microRNA-23~27~24 in ocular angiogenesis

Amy E. Pasquinelli, Ph.D.
Associate Professor of Molecular Biology
University of California at San Diego
La Jolla, California, USA
Title: The primary target of let-7 microRNA

Amanda Birmingham
Bioinformatics Manager
Thermo FisherScientific
Lafayette, CO, USA
Title: Better than the real thing: In Silico screens for statistical selection

Carl D. Novina MD, PhD.
Associate Professor of Microbiology & Immunobiology
Harvard Medical School &
Associate Member, Broad Institute of Harvard
Massachusetts Institute of Technology
Boston, Massachusetts, USA

Yuichi Taniguchi, PhD.
Unit Leader of Single Cell Gene Dynamics
RIKEN Quantitative Biology Center
Osaka, Japan
Title: Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells

Jonathan Cohen, PhD.
Researcher in Porter Neuroscience Research Ctr.
NICHD-National Institutes of Health
Bethesda, MD, USA
Title: Bioinformatics, microRNAs, and synaptic plasticity

Maha Abdellatif, PhD.
Professor of Cell Biology & Molecular Medicine
University of Medicine and Dentistry of New Jersey
Newark, New Jersey, USA
Title: Differential expression of microRNAs in cardiovascular diseases

Patrick Y. Lu, PhD.
President & Chief Executive Officer
Sirnaomics, Inc.
Gaithersburg, MD, USA
Title: Development of three generations of nanoparticles for novel siRNA therapeutics

Brian L. Murphy, PhD.
Research Fellow in Tumor Cell Biology
St. Jude Children's Research Hospital
Memphis, TN, USA
Title: Silencing of the miR-17~92 cluster by tiny LNAs suppresses Sonic Hedgehog medulloblastoma progression in vivo

Douglas Fambrough, PhD.
Chief Executive Officer
Dicerna Pharmaceuticals, Inc.
Watertown, MA, USA
Title: Delivery and efficacy of dicer substrate siRNAs (DsiRNAs) using EnCore lipid nanoparticles in multiple tumor models

Matthew Hsu, PhD.
Director of R&D - Bioscience Division
Merck Millipore
Temecula,California, USA
Title: miRNA profiling of cancer cells using SmartFlareTM, a novel live-cell RNA detection technology

Carmit Levy, PhD.
Principal investigator of Human Genetics & Biochemistry
Tel Aviv University-Sackler School of Medicine
Tel-Aviv, Israel
Title: Role of microRNA-221 in melanoma

Daniela B. Munafo, PhD.
Applications and Product Development Scientist
New England Biolabs, Inc.
Ipswich, Massachusetts, USA
Title: Highly performance methods of library preparation for small RNA discovery and analysis by deep Sequencing


Pavan Kumar, PhD.
Senior Scientist in Biomarkers Unit
Eisai, Inc.
Andover, MA, USA
Title: Current state of miRNAs as biomarkers

Marc Winnefeld, PhD.
Scientist, Research Division of Special Skincare
Beiersdorf AG
Hamburg, Germany
Title:: Identification of new targets involved in adipocyte differentiation by high throughput siRNA screening

John Doench, PhD.
Research Scientist in RNAi Platform
The Broad Institute of MIT and Harvard
Boston, MA, USA
Title: Bugs into Features -- miRNA off-target effects in genome-wide RNAi screens

Jiannis Ragoussis, PhD.
Head of Genome Sciences
McGill University, Montréal, Canada
Title: microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast Cancer

Anne Dallas, PhD.
Senior Scientist
Somagenics Inc.
Santa Cruz, CA, USA
Title: Minimal-length synthetic shRNAs (sshRNAs) have distinct and unusual Dicer-independent mechanisms of gene silencing

Dr. Masahiko Kuroda
Director of Bonac Corp &
Staff of the Tokyo Medical University
Tokyo, Japan
Title: Systemic delivery of antitumor microRNAs into breast cancer cells

1 May - 2 May 2013
Waltham
United States of America
meeting website