Cilia, Mucus & Mucociliary Interactions

he transport of mucus and other fluids by motile cilia is fundamental to human health and development. Disruption of this process in the respiratory tract due to ciliary dysfunction (as a result of primary ciliary dyskinesia) or alterations in the viscoelastic properties of mucus leads to severe pulmonary diseases such as cystic fibrosis and bronchitis. Similarly, alterations in cilia-driven fluid flow and disruption of extracellular signaling gradients during embryogenesis can result in a broad array of devastating developmental disorders (ciliopathies). This conference provides the unique opportunity for basic scientists and clinical researchers interested in these inter-related areas to discuss their latest findings and learn about new technologies that provide novel approaches to current challenges. This conference attracts a broad array of scientists ranging from biophysicists and biochemists to physiologists and geneticists. In addition, the conference format provides excellent opportunities for junior scientists to present their work and exchange ideas in a collegial atmosphere with leaders in the field. The meeting will begin on the Sunday evening with two keynote lectures by eminent scientists from the fields of cilia and mucus who will set out the current paradigms within these areas and provide insight into the key challenges for the future. This will be followed by eight sessions that will include a combination of invited presentations and short talks on the latest results selected from the abstracts received. Each session will be chaired by two discussion leaders who will provide brief overviews of the topics to be covered. These formal sessions will also include significant time for discussion. Furthermore, there will be additional opportunities for informal discussions during the afternoons and evenings. In addition, there will be two poster sessions which will allow for the in-depth presentation of new results.

Sessions to be included in the 2013 conference include:

Ciliary Assembly and Mucus Production
Biophysics of Cilia/Mucus Interactions
Differentiation of Multiciliated and Secretory Cells
Cilia, Flow and Tissue Development
Genomic/Proteomic/Glycomic Approaches to Ciliopathies and Muco-ciliary Disease
Cilia/Fluid Interactions
New Approaches to the Study of Cilia and Muco-ciliary Interactions
Model Systems in Understanding Ciliary Function and Muco-ciliary Disease

+ show speakers and program

Perspectives on Cilia and Mucus
(Martina Brueckner, David Thornton / George Witman / Jeffrey Wine)
Ciliary Assembly and Mucus Production
(Mary Rose, Winfield Sale / Eszter Vladar / David Erle / Esben Lorentzen / C. William Davis / Elizabeth Smith / Michael McGuckin)
Biophysics of Cilia/Mucus Interactions
(Stephen King, Richard Superfine / Raymond Goldstein / Richard Cone / Brian Button / Julian Vermot)
Differentiation of Multiciliated and Secretory Cells
(Burton Dickey, Susan Dutcher / Pascal Barbry / Jayaraj Rajagopal / Jeffrey Whitsett)
Cilia, Flow and Tissue Development
(Iain Drummond, Steven Brody / Joseph LoTurco / Zhaoxia Sun / Domminic Norris)
Genomic/Proteomic/Glycomic Approaches to Ciliopathies and Muco-ciliary Disease
(Heymut Omran, Pauline Rudd / Peter Jackson / Anne Dell / Gunnar Hansson / Hannah Mitchison / Susan Dutcher)
Cilia/Fluid Interactions
(Lawrence Ostrowski, Peter Satir / Iain Drummond / Greg Forest / Richard Superfine / Martin Blum)
New Approaches to the Study of Cilia and Muco-ciliary Interactions
(Peter Jackson / Maxence Nachury / Najl Valeyev / Alessandra Livraghi-Butrico / Camille Ehre / Claudius Werner)
From Protists to Mammals - Understanding Ciliary Function and Muco-ciliary Disease
(George Witman, Jeffrey Wine / Lawrence Ostrowski / Jacek Gaertig / Mustafa Khokha / Michael Welsh)

7 Apr - 12 Apr 2013
Barga
Italy
meeting website